Lipocalin-1: a potential marker for noninvasive aneuploidy screening

This study has identified the first protein, lipocalin-1, in the secretome of human blastocysts that is associated with chromosome aneuploidy. The development of a noninvasive technique to determine an embryo's developmental competence, including chromosomal constitution, by analysis of spent IVF culture medium will be a powerful tool for embryo selection in assisted reproductive technologies. (Fertil Steril (R) 2011;95:2631-3. (C) 2011 by American Society for Reproductive Medicine.)