Article
Obstetrics & Gynecology
Anna Joud, Emma Nilsson-Condori, Lone Schmidt, Soren Ziebe, Ditte Vassard, Kristina Mattsson
Summary: Women with asthma have comparable chances of giving birth compared to women without asthma, but they have a higher risk of infertility, pregnancy loss, and the need for medically assisted reproduction.
HUMAN REPRODUCTION
(2022)
Article
Public, Environmental & Occupational Health
Sha Huang, Jia Yi Hee, Yuxun Oswald Zhang, Ruofan Gongye, Siyu Zou, Kun Tang
Summary: This study found that pregnancy loss, especially spontaneous and induced abortions, is associated with an increased risk of COPD among Chinese women. However, a single pregnancy has a protective effect.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Virology
Carmen Elena Condrat, Lidia Filip, Mirela Gherghe, Dragos Cretoiu, Nicolae Suciu
Summary: HPV infection, commonly transmitted through direct contact of infected organs, is a prevalent sexually transmitted infection posing a high risk to young women, potentially leading to various malignancies. Recent studies have also shown harmful effects of HPV infection on pregnancy outcomes, including adverse conditions such as preterm birth, intrauterine growth restriction, and fetal death.
Article
Obstetrics & Gynecology
Ling-Jun Li, Ruochen Du, See Ling Loy, Yap Seng Chong, Jerry Kok Yen Chan, Tien Yin Wong, Johan G. Eriksson, Zhongwei Huang, Cuilin Zhang
Summary: This prospective study involving 1,032 Southeast Asian women found that retinal microvascular features were associated with the risk of spontaneous abortion.
FERTILITY AND STERILITY
(2022)
Article
Obstetrics & Gynecology
Periyasamy Kuppusamy, Ranjan K. Prusty, Itta K. Chaaithanya, Rahul K. Gajbhiye, Geetanjali Sachdeva
Summary: This study examines the trends in pregnancy outcomes among Indian women from 2015 to 2021. The findings indicate a decrease in livebirth and an increase in miscarriage and stillbirth. It highlights the need for region-specific, comprehensive, and high-quality maternal healthcare programs for Indian women.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Review
Virology
Carmen Elena Condrat, Dragos Cretoiu, Viorica Elena Radoi, Dana Mihaela Mihele, Mihaela Tovaru, Cristian Ioan Bordea, Silviu Cristian Voinea, Nicolae Suciu
Summary: This review explores the immunological changes in pregnant women with HPV and aims to uncover strategies for safely modulating the immune system, mitigating adverse pregnancy consequences, and enhancing maternal and child health. It is of significant importance in understanding the risks of HPV infection during pregnancy.
Article
Endocrinology & Metabolism
Ines Braham, Adeline Morisot, Samir Boukaidi, Marie Perceval, Isabelle Durieu, Christine Rousset-Jablonski, Sylvie Hieronimus, Sylvie Leroy, Nicolas Chevalier
Summary: This study investigated the causes of infertility, appropriate ART treatment, and pregnancy outcomes in women with cystic fibrosis. The results showed that CF women had slightly lower antral follicle count, but there was no significant difference in the causes of infertility, the number of oocytes and embryos obtained, and pregnancy outcomes compared to non-CF women. In the absence of any other pathology, IUI may be the first option for CF women.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Anil Sigdel, Rafael S. Bisinotto, Francisco Penagaricano
Summary: This study provides evidence that fetal loss is heritable and can be reduced through genetic selection. Fetal loss is largely independent from current breeding efforts to improve cow fertility.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Obstetrics & Gynecology
Annemieke Hoek, Zheng Wang, Anne M. van Oers, Henk Groen, Astrid E. P. Cantineau
Summary: Obesity can negatively impact natural fertility in both men and women, as well as pregnancy chances. Lifestyle intervention is recommended as the first-line treatment for obesity, with or without medical treatments. Investigating the effects of lifestyle intervention on reproductive outcomes is crucial.
FERTILITY AND STERILITY
(2022)
Article
Obstetrics & Gynecology
Filipa Rafael, Maria Dias Rodrigues, Jose Bellver, Mariana Canelas-Pais, Nicolas Garrido, Juan A. Garcia-Velasco, Sergio Reis Soares, Samuel Santos-Ribeiro
Summary: For women with infertility and overweight/obesity, delaying infertility treatment to promote weight loss should consider female age. Substantial weight loss in a short period of time (3 months) seems to provide any benefit, particularly for women over 38 years old.
HUMAN REPRODUCTION
(2023)
Article
Endocrinology & Metabolism
Yanhua Qi, Yuemin Hou, Miaoyan Ma, Xiaopeng Li, Jinfang Wu
Summary: This study found that the serum concentration of Elabela was significantly lower in MA patients compared to healthy pregnant women, indicating that Elabela may serve as an important biomarker for the pathophysiological process in MA.
GYNECOLOGICAL ENDOCRINOLOGY
(2022)
Article
Veterinary Sciences
Mohammad Shamim Hossein, Young-Bum Son, Yeon Ik Jeong, Mina Kang, Seejin Lee, Alex Tinson, Woo Suk Hwang
Summary: This article reports a case of monoamniotic twin abortion in a dromedary camel and discusses the rarity and significance of this condition in livestock species.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Review
Andrology
Nicolaj Bruun Brandt, Maria Louise Skovbo Kristensen, Laura Catalini, Jens Fedder
Summary: Paternal health, especially cardiovascular and metabolic health, is positively associated with the risk of pregnancy loss. Factors such as paternal age and somatic health also play a role in this association, while the impact of diabetes on pregnancy loss may be less significant. Further research is needed to provide more conclusive evidence on the relationship between paternal health and pregnancy loss.
Article
Obstetrics & Gynecology
Michal Youngster, Sarit Avraham, Odelia Yaakov, Moran Landau Rabbi, Itai Gat, Gil Yerushalmi, Rachael Sverdlove, Micha Baum, Ettie Maman, Ariel Hourvitz, Alon Kedem
Summary: This retrospective cohort study found that prior SARS-CoV-2 infection does not affect the outcomes of fresh ART cycles in women, except for a possible long-term negative effect on oocyte yield (>180 days postinfection).
HUMAN REPRODUCTION
(2022)
Article
Obstetrics & Gynecology
Maria Teresa Bruno, Salvatore Caruso, Francesca Bica, Giulia Arcidiacono, Sara Boemi
Summary: This study demonstrates that papillomavirus DNA can infect the placenta and that placental HPV infection can occur as early as the first trimester of pregnancy.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Obstetrics & Gynecology
Roberta Granese, Antonino Perino, Gloria Calagna, Salvatore Saitta, Pasquale De Franciscis, Nicola Colacurci, Onofrio Triolo, Gaspare Cucinella
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2015)
Article
Obstetrics & Gynecology
Attilio Di Spiezio Sardo, Gloria Calagna, Maurizio Guida, Antonio Perino, Carmine Nappi
BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY
(2015)
Review
Obstetrics & Gynecology
Emanuela Orlandi, Cinzia Rossi, Antonio Perino, Gaspare Cucinella, Francesco Orlandi
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2016)
Article
Oncology
Francesco Paolo Fiorentino, Elvan Tokgun, Sonia Sole-Sanchez, Sabrina Giampaolo, Onur Tokgun, Toni Jauset, Takashi Kohno, Manuel Perucho, Laura Soucek, Jun Yokota
Article
Oncology
Fuyumi Kato, Francesco Paolo Fiorentino, Andreu Alibes, Manuel Perucho, Montse Sanchez-Cespedes, Takashi Kohno, Jun Yokota
Article
Cell Biology
Irene Marchesi, Luca Sanna, Milena Fais, Francesco P. Fiorentino, Antonio Giordano, Luigi Bagella
JOURNAL OF CELLULAR PHYSIOLOGY
(2018)
Article
Cell Biology
Francesco P. Fiorentino, Luigi Bagella, Irene Marchesi
JOURNAL OF CELLULAR PHYSIOLOGY
(2018)
Article
Biochemistry & Molecular Biology
Onur Tokgun, Francesco Paolo Fiorentino, Pervin Elvan Tokgun, Jun Yokota, Hakan Akca
MOLECULAR BIOTECHNOLOGY
(2017)
Correction
Biochemistry & Molecular Biology
Onur Tokgun, Francesco Paolo Fiorentino, Pervin Elvan Tokgun, Jun Yokota, Hakan Akca
MOLECULAR BIOTECHNOLOGY
(2017)
Article
Biotechnology & Applied Microbiology
Giuseppina Capra, Lucia Giovannelli, Domenica Matranga, Carmelina Bellavia, Maria Francesca Guarneri, Teresa Fasciana, Giovanna Scaduto, Alberto Firenze, Alessandra Vassiliadis, Antonio Perino
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2017)
Article
Biochemistry & Molecular Biology
Francesco Paolo Fiorentino, Irene Marchesi, Christoph Schroder, Ronny Schmidt, Jun Yokota, Luigi Bagella
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Medicine, Research & Experimental
Patrizia Virdis, Rossana Migheli, Valentina Bordoni, Francesco Paolo Fiorentino, Luca Sanna, Irene Marchesi, Giorgio Pintore, Grazia Galleri, Maria Rosaria Muroni, Luigi Bagella, Claudio Fozza, Maria Rosaria De Miglio, Luigi Podda
Summary: The study evaluated the potential antitumor activity of tomentosin on human RPMI-8226 cells by increasing tomentosin concentration for cytotoxicity screening. Results showed that tomentosin may explain its antiproliferative effects through cell cycle arrest and apoptosis, leading to inhibition of cell viability in RPMI-8226 cells.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
(2021)
Article
Biology
Patrizia Virdis, Irene Marchesi, Francesco Paolo Fiorentino, Rossana Migheli, Luca Sanna, Valentina Bordoni, Giorgio Pintore, Grazia Galleri, Maria Rosaria Muroni, Luigi Bagella, Claudio Fozza, Maria Rosaria De Miglio, Luigi Podda
Summary: The sesquiterpene lactone tomentosin extracted from I. viscosa has shown promising anti-tumor properties in therapeutic oncologic fields. This study demonstrates that tomentosin exerts its antiproliferative effects through cell cycle arrest and induction of cell apoptosis in Burkitt's lymphoma cells. The microarray gene expression analysis revealed 75 deregulated genes, with downregulated genes enriched in pathways favoring proliferation, and upregulated genes related to cellular death, particularly apoptosis. Overall, tomentosin shows potential as a natural product with limited toxicity and significant anti-tumoral activity for BL patients.
Article
Biochemistry & Molecular Biology
Irene Marchesi, Milena Fais, Francesco Paolo Fiorentino, Valentina Bordoni, Luca Sanna, Stefano Zoroddu, Luigi Bagella
Summary: The effects of BET inhibitor JQ1 on the viability of RMS cells were evaluated in this study. It was found that the drug sensitivity of RMS cell lines to JQ1 was directly proportional to the expression of MYC. JQ1 induced G1 arrest in cells with high steady-state levels of MYC, and apoptosis was associated with MYC downregulation. These findings suggest that BET inhibition could be an effective strategy for the treatment of RMS.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Camille Jacques, Irene Marchesi, Francesco Paolo Fiorentino, Mathias Chatelais, Nicoletta Libera Lilli, Kurt Appel, Beatrice Lejeune, Ilaria Floris
Summary: This study evaluated the immunomodulatory effects of MIM-seq on human macrophages and its potential anti-tumor properties against colorectal cancer (CRC). The results showed that MIM-seq inhibited pro-inflammatory cytokine secretion and displayed anti-proliferative effects on tumor cells. When combined with other anti-cancer agents, MIM-seq further reduced tumor growth, suggesting its potential as an adjuvant therapy for CRC patients.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
