期刊
FERTILITY AND STERILITY
卷 95, 期 6, 页码 1950-U107出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2011.01.151
关键词
Antral follicle count; decreased ovarian reserve; DOR; unexplained infertility; subfertile; FSH
资金
- National Institute of Child Health and Human Development/National Institute on Aging [R01HD044876]
Objective: To determine whether infertile women have lower antral follicle counts (AFC) than age-matched normal women. Design: Case-control. Setting: Academic center. Patient(s): A total of 881 infertile women and 771 women from the community. Intervention(s): Antral follicle count and basal hormone measurements. Main Outcome Measure(s): Median AFCs and FSH levels were compared between the two groups within 5-year age strata by using the median test. A subanalysis was performed by identifying women in the control group with a history of attempting conception without success (subfertile group) and with a spontaneous conception in fewer than 12 months resulting in a live birth (fertile group). Age-specific AFC percentiles were calculated and compared within strata determined by age at the time of attempted conception. Result(s): AFCs were significantly lower in infertile women than in control women across age groups up to 40 years of age. Average FSH levels were significantly higher in the younger-age infertile group versus the community. AFC percentiles differ significantly between fertile and subfertile women within the community up to 40 years of age. Conclusion(s): Decreased AFC in infertile women suggests that factors affecting the size of the remaining follicle pool in younger women also affect oocyte quality and the likelihood of conception. (Fertil Steril (R) 2011; 95: 1950-4. (C)2011 by American Society for Reproductive Medicine.)
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据