期刊
FERTILITY AND STERILITY
卷 95, 期 6, 页码 2150-2152出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2010.12.009
关键词
Metabolic syndrome; metformin; OTA; semen; testosterone
To examine the appropriate treatment of oligo-terato-asthenozoospermic patients with metabolic syndrome, 45 patients were treated with metformin for 6 months. The use of metformin was associated with a statistically significant reduction in insulin resistance and sex hormone-binding globulin levels, a statistically significant increase in serum androgen levels, and a consequent improvement in semen characteristics. (Fertil Steril (R) 2011;95:2150-2. (C) 2011 by American Society for Reproductive Medicine.)
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