期刊
FERTILITY AND STERILITY
卷 95, 期 1, 页码 338-341出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2010.08.006
关键词
Stem cells; SOX-2; KLF-4; NANOG; OCT-4; endometriosis; endometrium; telomerase; induced pluripotent stem cells; adenomyosis
Expression of the pluripotency factors SOX-2, OCT-4, KLF-4, and NANOG was analyzed by quantitative real-time polymerase chain reaction, immunohistochemistry, and immunofluorescence microscopy in the endometrium, myometrium, and endometriotic tissue of 36 patients. Aberrant expression of SOX-2 may indicate a stem cell origin of endometriosis, whereas the presence of all progenitor markers in endometrial tissue marks the endometrium as a potential source for induced pluripotent stem cell generation. (Fertil Steril (R) 2011; 95:338-41. (c) 2011 by American Society for Reproductive Medicine.)
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