Article
Medicine, General & Internal
Wen-Bin Wu, Hsuan-Ting Chen, Jun-Jie Lin, Tsung-Hsuan Lai
Summary: The study revealed a negative association between follicular fluid VEGF concentration and ovarian reserve level, as well as oocyte maturation rate in patients undergoing GnRH antagonist IVF protocols. Additionally, a negative correlation was found between follicular fluid VEGF concentration and serum anti-Mullerian hormone (AMH) level. Oocyte maturation rate tended to increase at higher AMH levels.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Cell Biology
Bikem Soygur, Diana J. Laird
Summary: The ovary is essential for female reproduction and health, but studying its function in mammals faces challenges due to unique characteristics. Advances in optical tissue clearing and 3D visualization technologies have provided a platform to explore the structure of the ovary and have potential applications in treating ovarian diseases and extending female reproductive lifespan.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Oncology
Lin Yan, Ling Ren, Yingying Li, Yukun Luo
Summary: This study investigated the inter-observer reliability and agreement of two-dimensional ultrasound (2DUS) and three-dimensional ultrasound (3DUS) in measuring the maximum diameter and volume of papillary thyroid microcarcinoma (PTMC). The results showed that the maximum diameter had the lowest degree of observer variation, and the volume measured by 3DUS had lower variability and higher repeatability compared to 2DUS.
Article
Cell Biology
E. Fang, He Zhang, Wanli Yin, Chongyang Wang, Yuanli Liu, Yanze Li, Linlin Wang, Yue Wu, Runze Zhang, Chendan Zou, Tianjun Song, Cedric Matunda, Chaoxia Zou, Xu Gao
Summary: This study reveals the essential role of CPEB3 in ovarian follicle development and female fertility, as it regulates the expression of Gdf9 in oocytes. Cpeb3-mutant mice exhibit a phenotype similar to POI, providing new insights for the understanding and treatment of POI.
CELL DEATH & DISEASE
(2022)
Review
Biochemistry & Molecular Biology
Mengchi Chen, Haotian Jiang, Chunping Zhang
Summary: Primary ovarian insufficiency (POI) is a heterogeneous disease characterized by non-functional ovaries in women under 40. Genetic factors play a crucial role in POI cases, accounting for around 20% to 25%. This paper reviews various genetic causes of POI, including chromosomal abnormalities, single gene mutations, defects in mitochondrial functions, and non-coding RNA abnormalities, providing valuable insights for diagnosing and predicting POI.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Medicine, General & Internal
Qian Chen, Lu Sun, Jian Huang, Fan Huang, Shuang Guo, Yiqing Chai
Summary: The applicability of three-dimensional transvaginal ultrasonography (3D-TVS) in evaluating diminished ovarian reserve (DOR) and premature ovarian failure (POF) was explored in this study. 120 female patients were included and divided into DOR-group, POF-group, and Normal-group for analysis. The results showed that the 3D-TVS examination indexes of the DOR-group and POF-group were significantly lower than the Normal-group. The diagnostic specificity, sensitivity, and accuracy of 3D-TVS for DOR were 80%, 90%, and 88% respectively, while for POF, they were 87.5%, 95.8%, and 93.8% respectively. 3D-TVS can provide scientific guidance for the clinical diagnosis and evaluation of DOR and POF.
PAKISTAN JOURNAL OF MEDICAL SCIENCES
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Wonseok Choi, Eun-Yeong Park, Seungwan Jeon, Yeoree Yang, Byullee Park, Joongho Ahn, Seonghee Cho, Changyeop Lee, Dong-Kyo Seo, Jae-Hyoung Cho, Chulhong Kim
Summary: This study investigated a three-dimensional noncontrast bimodal photoacoustic/ultrasound imaging system to quantitatively and reliably assess the microcirculation of the human foot noninvasively. The imaging system was able to visualize the morphologic and physiologic features of the foot, including the peripheral microvasculature, in healthy volunteers.
Article
Obstetrics & Gynecology
Xiaowen Liang, Jiamin Liang, Fengyi Zeng, Yan Lin, Yuewei Li, Kuan Cai, N. Dong, Zhiyi Chen
Summary: This study established a novel biomarker for assessing oocyte maturity, timing of HCG administration, and individual prediction of ovarian hyper-response using deep learning-based segmentation algorithms and multivariate classifiers based on three-dimensional ultrasound (3D-US). The results showed that the performance of the novel biomarker was significantly better than conventional methods in predicting the number of mature oocytes retrieved and optimizing HCG trigger timing. Furthermore, the accuracy of the multi-layer perceptron model was better than other classifiers in predicting ovarian hyper-response.
REPRODUCTIVE BIOMEDICINE ONLINE
(2022)
Article
Cardiac & Cardiovascular Systems
Tara Neleman, Alessandra Scoccia, Frederik T. W. Groenland, Annemieke C. Ziedses des Plantes, Laurens J. C. van Zandvoort, Jurgen M. R. Ligthart, Karen T. Witberg, Mattie J. Lenzen, Eric Boersma, Rutger-Jan Nuis, Wijnand K. den Dekker, Roberto Diletti, Jeroen Wilschut, Felix Zijlstra, Nicolas M. Van Mieghem, Joost Daemen
Summary: This study evaluates the diagnostic performance of post-PCI pressure gradients to detect residual focal lesions and stent underexpansion. The results show that post-PCI FFR gradients can effectively predict IVUS-detected distal and proximal lesions, while Pd/Pa and dPR gradients have poor predictive ability. Gradients within the stent are not useful for detecting stent underexpansion.
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Multidisciplinary Sciences
Flavien Bureau, Justine Robin, Arthur Le Ber, William Lambert, Mathias Fink, Alexandre Aubry
Summary: Matrix imaging is revolutionizing wave physics by optimizing compensation for aberrations and multiple scattering in heterogeneous media. This paper extends ultrasound matrix imaging to a 3D geometry and proposes a non-invasive approach to make the skull transparent for improved brain imaging.
NATURE COMMUNICATIONS
(2023)
Article
Biochemistry & Molecular Biology
Yingjun Chen, Qinghua Liu, Ruiyan Liu, Chan Yang, Xiaodong Wang, Zaohong Ran, Shanshan Zhou, Xiang Li, Changjiu He
Summary: This study in a mouse model revealed that early folliculogenesis requires a minimum of two weeks, with different stages showing specific characteristics such as oocyte size at Type 4-5 stage and theca folliculi formation at PD10-12. The study also highlighted the importance of the PD22-23 period for studying puberty initiation, providing valuable insights into the biological events of this process.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Reproductive Biology
Shinichiro Shirouzu, Naohiro Sugita, Narantsog Choijookhuu, Yu Yamaguma, Kanako Takeguchi, Takumi Ishizuka, Mio Tanaka, Fidya Fidya, Kengo Kai, Etsuo Chosa, Yoshihiro Yamashita, Chihiro Koshimoto, Yoshitaka Hishikawa
Summary: This study revealed the essential role of HMGB2 in ovarian folliculogenesis and fertilization, with its depletion leading to alterations in ovarian morphology and function.
JOURNAL OF OVARIAN RESEARCH
(2022)
Article
Agriculture, Dairy & Animal Science
Shenqiang Hu, Mou Zhu, Jiwen Wang, Liang Li, Hua He, Bo Hu, Jiwei Hu, Lu Xia
Summary: This study compared the histomorphological and molecular changes of primordial, primary, and secondary follicles in duck and goose ovaries during the first 6 weeks post hatching. The results showed that duck ovaries exhibited a faster growth rate for ovarian follicles compared to geese, with earlier appearance of secondary follicles. Differential expression profiles of FSHR, AMH, and CASPASE3 may contribute to these differences in early folliculogenesis between ducks and geese.
Review
Biochemistry & Molecular Biology
Kenya Imaimatsu, Aya Uchida, Ryuji Hiramatsu, Yoshiakira Kanai
Summary: This article discusses the mechanism of gonadal sex differentiation along the cortical-medullary axis and compares the features of the cortical and medullary regions of the ovary in mammalian species.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Multidisciplinary Sciences
Shan Lei, Jing Zhang, Nicholas Thomas Blum, Meng Li, Dong-Yang Zhang, Weimin Yin, Feng Zhao, Jing Lin, Peng Huang
Summary: The study demonstrates the use of three-dimensional multispectral photoacoustic molecular imaging to monitor cascade catalytic therapy in vivo, and shows its potential application in tumor treatment.
NATURE COMMUNICATIONS
(2022)
Editorial Material
Acoustics
A. Ludwin
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2018)
Article
Acoustics
M. Prior, A. Richardson, S. Asif, L. Polanski, M. Parris-Larkin, J. Chandler, L. Fogg, P. Jassal, J. G. Thornton, N. J. Raine-Fenning
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2018)
Correction
Acoustics
A. Khalil, M. Rodgers, A. Baschat, A. Bhide, E. Gratacos, K. Hecher, M. D. Kilby, L. Lewi, K. H. Nicolaides, D. Oepkes, N. Raine-Fenning
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2018)
Article
Obstetrics & Gynecology
Edward Coats, Hannah Carden, Lyndsey Zujovic, Walid Maalouf, James Hopkisson, Nicholas Raine-Fenning
Article
Medicine, General & Internal
Rima K. Dhillon-Smith, Lee J. Middleton, Kirandeep K. Sunner, Versha Cheed, Krys Baker, Samantha Farrell-Carver, Ruth Bender-Atik, Rina Agrawal, Kalsang Bhatia, Edmond Edi-Osagie, Tarek Ghobara, Pratima Gupta, Davor Jurkovic, Yacoub Khalaf, Marjory MacLean, Christopher McCabe, Khashia Mulbagal, Natalie Nunes, Caroline Overton, Siobhan Quenby, Raj Rai, Nick Raine-Fenning, Lynne Robinson, Jackie Ross, Andrew Sizer, Rachel Small, Alex Tan, Martyn Underwood, Mark D. Kilby, Kristien Boelaert, Jane Daniels, Shakila Thangaratinam, Shiao Y. Chan, Arri Coomarasamy
NEW ENGLAND JOURNAL OF MEDICINE
(2019)
Article
Obstetrics & Gynecology
Amal Mohammed, Kathryn J. Woad, George E. Mann, Jim Craigon, Nick Raine-Fenning, Robert S. Robinson
FERTILITY AND STERILITY
(2019)
Article
Public, Environmental & Occupational Health
Abha Maheshwari, Siladitya Bhattacharya, Ursula Bowler, Daniel Brison, Tim Child, Christina Cole, Arri Coomarasamy, Rachel Cutting, Stephen Harbottle, Pollyanna Hardy, Edmund Juszczak, Yacoub Khalaf, Jennifer J. Kurinczuk, Stuart Lavery, Clare Lewis-Jones, Nick Macklon, Nick J. Raine-Fenning, Madhurima Rajkohwa, Graham Scotland, Stephen Troup
REPRODUCTIVE HEALTH
(2019)
Article
Endocrinology & Metabolism
Rima K. Dhillon-Smith, Aurelio Tobias, Paul P. Smith, Lee J. Middleton, Kirandeep K. Sunner, Krystyna Baker, Samantha Farrell-Carver, Ruth Bender-Atik, Rina Agrawal, Kalsang Bhatia, Justin J. Chu, Edmond Edi-Osagie, Ayman Ewies, Tarek Ghobara, Pratima Gupta, Davor Jurkovic, Yacoub Khalaf, Khashia Mulbagal, Natalie Nunes, Caroline Overton, Siobhan Quenby, Raj Rai, Nick Raine-Fenning, Lynne Robinson, Jackie Ross, Andrew Sizer, Rachel Small, Martyn Underwood, Mark D. Kilby, Jane Daniels, Shakila Thangaratinam, Shiao Chan, Kristien Boelaert, Arri Coomarasamy
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2020)
Article
Public, Environmental & Occupational Health
Nicky Hudson, Caroline Law, Lorraine Culley, Helene Mitchell, Elaine Denny, Wendy Norton, Nick Raine-Fenning
SOCIOLOGY OF HEALTH & ILLNESS
(2020)
Article
Public, Environmental & Occupational Health
Nicky Hudson, Caroline Law, Lorraine Culley, Helene Mitchell, Elaine Denny, Nick Raine-Fenning
Review
Medicine, General & Internal
Laurentiu Craciunas, Nikolaos Tsampras, Nick Raine-Fenning, Arri Coomarasamy
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2018)
Meeting Abstract
Obstetrics & Gynecology
M. Prior, J. Hopkisson, N. Raine-Fenning
HUMAN REPRODUCTION
(2018)
Meeting Abstract
Obstetrics & Gynecology
I. Sfontouris, A. Patelakis, G. Panitsa, S. Theodoratos, N. Raine-Fenning
HUMAN REPRODUCTION
(2018)
Review
Medicine, General & Internal
Danielle M. Teixeira, Andre H. Miyague, Mariana A. P. Barbosa, Paula A. Navarro, Nick Raine-Fenning, Carolina O. Nastri, Wellington P. Martins
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2020)
Letter
Obstetrics & Gynecology
Rachel Hibberd, Nick Raine-Fenning, Jim Thornton
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2018)