Article
Oncology
Rohit R. Badia, Akshat Patel, Nathan Chertack, Jeffrey M. Howard, Aditya Bagrodia, Tolulope Bakare
Summary: This study aimed to investigate the impact of testicular cancer stage and histology on semen parameters in preorchiectomy cryopreservation samples. The results showed that semen parameters were similar across different stages of testicular cancer and did not significantly differ between different histology types. Therefore, regardless of the stage or histology, sperm banking should be recommended for patients with both localized and metastatic testicular cancer.
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
(2023)
Review
Chemistry, Analytical
Yu Fang, Ruige Wu, Joo Mong Lee, Ling Hou Melinda Chan, Kok Yen Jerry Chan
Summary: The field of assisted reproductive technology (ART) has been constantly improving, and microfluidic technology has the potential to play a transformative role in optimizing embryo development. Microfluidics can be integrated into various stages of embryo production, enabling miniaturization, integration, and automation. Progress in 3D printing technology, organ-on-a-chip, alternative materials, and integrated microfluidic operational units will drive the development of this technology. An ideal microfluidic system would incorporate oocyte processing, sperm processing, and embryo culture into a single compact device. This article reviews the recent applications of microfluidic technologies in IVF procedures and discusses the challenges and potentials for their application in ART.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Oncology
Lohith Chengappa Appaneravanda, Brigitte Gerstl, Ashwini Nagaraju, Arun Kumar, Indrani Sanna Balamukund, Devika Gunasheela
Summary: The study found that Indian men with malignancies, particularly testicular cancer patients, have lower semen quality compared to other cancer groups, with significantly lower sperm concentration. These findings suggest an increased risk of infertility among testicular cancer patients.
JOURNAL OF ADOLESCENT AND YOUNG ADULT ONCOLOGY
(2021)
Article
Oncology
Renee L. Mulder, Anna Font-Gonzalez, Daniel M. Green, Erik A. H. Loeffen, Melissa M. Hudson Jacqueline, Jacqueline Loonen, Richard Yu, Jill P. Ginsberg, Rod T. Mitchell, Julianne Byrne, Roderick Skinner, Antoinette Anazodo, Louis S. Constine, Andrica de Vries, Kirsi Jahnukainen, Armando Lorenzo, Andreas Meissner, Leena Nahata, Marij Dinkelman-Smit, Herman Tournaye, Riccardo Haupt, Marry M. van den Heuvel-Eibrink, Hanneke M. van Santen, Ans M. M. van Pelt, Uta Dirksen, Jaap den Hartogh, Eline van Dulmen-den Broeder, W. Hamish Wallace, Jennifer Levine, Wim J. E. Tissing, Leontien C. M. Kremer, Lisa B. Kenney, Marianne D. van de Wetering
Summary: This clinical practice guideline provides guidance on risk assessment and fertility preservation methods for male patients diagnosed with childhood, adolescent, and young adult cancer at age 25 or younger. By rigorously evaluating existing evidence, transparent and easy-to-use recommendations are developed to facilitate the care of male patients at high risk of fertility impairment.
Article
Agriculture, Dairy & Animal Science
Shaimaa K. Hamad, Ahmed M. Elomda, Yanyan Sun, Yunlei Li, Yunhe Zong, Jilan Chen, Ahmed O. Abbas, Farid K. R. Stino, Ali Nazmi, Gamal M. K. Mehaisen
Summary: This study aims to evaluate the impact of different concentrations (3%, 6%, or 9%) of dimethylacetamide (DMA) as a cryoprotectant on post-thawed sperm quality, motility, antioxidant-biomarkers, and the expression of anti-freeze related genes. The results showed that 3% DMA group maintained higher post-thawed sperm quality compared to the other tested groups, with improvements in motility, viability, and antioxidant enzyme activity. Additionally, certain anti-freeze related genes were upregulated in the 3% DMA group.
Article
Urology & Nephrology
Michael B. Tradewell, Jesse Ory, Daniel E. Nassau, Andrew H. Rezk, Emad Ibrahim, Ranjith Ramasamy
Summary: Men with a solitary testis have higher serum follicle-stimulating hormone levels and a higher prevalence of compensated hypogonadism compared to men with bilateral testes, indicating a pituitary strain. Further followup is needed to assess potential detrimental consequences of this compensated state on testicular function.
JOURNAL OF UROLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
Guillaume Domain, Hiba Ali Hassan, Eline Wydooghe, Osvaldo Bogado Pascottini, Anders Johannisson, Jane M. Morrell, Wojciech Nizanski, Ann Van Soom
Summary: This study investigated the use of single layer centrifugation (SLC) to select the best-quality spermatozoa before freezing dog semen. The results showed that SLC was effective in separating spermatozoa based on their quality, resulting in better quality spermatozoa after thawing compared to standard centrifugation. However, spermatozoa from suboptimal semen quality did not survive freezing as well as those from optimal semen quality, even after using SLC. Although SLC allows for the isolation of high-quality spermatozoa and improves sperm sample quality after thawing, it does not improve the inherent freezing ability of suboptimal semen quality. Eighteen pups have been born so far using SLC-selected frozen-thawed semen, demonstrating the fertility of these selected spermatozoa.
Article
Andrology
Charles Scott, Kawa Omar, Hussain M. Alnajjar, Constantine Alifrangis, Kamran Ahmed, Asif Muneer
Summary: The introduction of a patient-centric pathway for managing suspected testicular cancer significantly increases the uptake of semen cryopreservation, especially for men within the common age for paternity. This pathway also helps to identify men who may benefit from microdissection oncoTESE for complex cases.
Review
Endocrinology & Metabolism
Tarique Hussain, Mahmoud Kandeel, Elsayed Metwally, Ghulam Murtaza, Dildar Hussain Kalhoro, Yulong Yin, Bie Tan, Muhammad Ismail Chughtai, Anjaleena Yaseen, Ali Afzal, Muhammad Saleem Kalhoro
Summary: Male infertility is a global issue with oxidative stress being the main contributing factor, affecting sperm quality and quantity. Dysfunction of mitochondria and inflammation also play important roles in compromised fertility. The interaction between oxidative stress and seminal plasma proteomes further influences male infertility. Understanding these factors can help improve strategies to prevent male infertility.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Violeta Igna, Ada Telea, Tiana Florea, Roxana Popp, Adrian Grozea
Summary: The decline in sturgeon populations, including Russian sturgeons, has reached alarming levels, threatening these species with extinction. Reproductive biotechnologies and fish farms are viable solutions to repopulate and meet the demands for sturgeon products. However, standard methods for cryopreservation of sturgeon spermatozoa and semen quality evaluation have yet to be identified. This study provides additional information on cryopreservation techniques and semen quality evaluation for Russian sturgeons.
Article
Oncology
Keji Li, Xin Liu, Yansong Huang, Xiaoli Liu, Qian Song, Ran Wang
Summary: This study investigated the application of ultrasound elastography and color Doppler ultrasound in evaluating testicular spermatogenic function in patients with varicocele-related infertility, finding that ultrasound elastography can predict the semen quality in these patients.
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH
(2021)
Article
Agriculture, Dairy & Animal Science
Christin Selige, Monike Quirino, Filip Schroeter, Matteo Aepli, Martin Schulze
Summary: Pasteurized egg yolk (PEY) can be used as a substitute for egg yolk in the diluents for boar semen cryopreservation without significant effects on sperm motility and morphology, although it may slightly affect mitochondrial activity and membrane integrity. Further studies are required to determine the impact of PEY on the fertilizing capacity of boar ejaculates.
REPRODUCTION IN DOMESTIC ANIMALS
(2021)
Article
Fisheries
Sen Yang, Zhilu Zeng, Xinghan Chen, Bin Fan, Zining Meng
Summary: This study aimed to assess the effect of melatonin addition on post-thaw sperm function of giant grouper. The results showed that melatonin improved the total motility, progressive motility, mitochondrial membrane potential, and velocity of frozen-thawed sperm. Melatonin also reduced apoptotic-like changes, increased sperm viability, and decreased DNA damage. Additionally, melatonin supplementation improved the fertility and hatching rate of cryopreserved giant grouper sperm, with a recommended concentration of 1-2 μM in the cryomedium.
AQUACULTURE REPORTS
(2023)
Review
Agriculture, Dairy & Animal Science
Qudratullah Kalwar, Min Chu, Rashid Ali Korejo, Hidayatullah Soomro, Ping Yan
Summary: This article reviews the cryopreservation of yak semen and the research efforts to improve the cryopreservation process. Global climate change has negatively impacted yak habitats and population sizes, leading researchers to investigate artificial yak reproduction. Sperm cryopreservation plays a crucial role in livestock production by promoting genetic diversity and the worldwide dispersal of animals with enhanced genetics. However, there are challenges in achieving high post-thaw viability and fertility of sperm, which require further research and improvement.
Article
Environmental Sciences
Aldo E. Calogero, Maria Fiore, Filippo Giacone, Maria Altomare, Paola Asero, Caterina Ledda, Giulietta Romeo, Laura M. Mongioi, Chiara Copat, Maria Giuffrida, Enzo Vicari, Salvatore Sciacca, Margherita Ferrante
Summary: The study found that environmental exposure to lead and cadmium contributes to a decline in human semen quality, while selenium may have beneficial effects. Measurements of metals/metalloids in the seminal fluid may be more predictive of semen quality than conventional blood measurements.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)