期刊
FEMS MICROBIOLOGY LETTERS
卷 353, 期 2, 页码 151-156出版社
OXFORD UNIV PRESS
DOI: 10.1111/1574-6968.12418
关键词
Enterococcus faecium; biofilm; virulence
类别
资金
- NIH from NIAID [R01 AI067861]
Enterococcus faecium, a major cause of nosocomial infections, is often isolated from conditions where biofilm is considered to be important in the establishment of infections. We investigated biofilm formation among E.faecium isolates from diverse sources and found that the occurrence and amount of biofilm formation were significantly greater in clinical isolates than fecal isolates from community volunteers. We also found that the presence of the emp(fm) (E. faecium pilus) operon was associated with the amount of biofilm formation. Furthermore, we analyzed the possible association between the distribution of 16 putative virulence genes and the occurrence of biofilm production. Even though the prevalence of these virulence genes was significantly higher in clinical isolates, we did not observe any correlation with the occurrence of biofilm formation.
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