Small animal models for the study ofClostridium difficiledisease pathogenesis

Murine models to study Clostridium difficile infection and transmission

(2013) Trevor D. Lawley et al.   ANAEROBE

Adaptive Strategies and Pathogenesis of Clostridium difficile fromIn VivoTranscriptomics

(2013) Claire Janoir et al.   INFECTION AND IMMUNITY

Importance of Toxin A, Toxin B, and CDT in Virulence of an Epidemic Clostridium difficile Strain

(2013) Sarah A. Kuehne et al.   JOURNAL OF INFECTIOUS DISEASES

Susceptibility of Hamsters to Clostridium difficile Isolates of Differing Toxinotype

(2013) Anthony M. Buckley et al.   PLoS One

Intrarectal Instillation of Clostridium difficile Toxin A Triggers Colonic Inflammation and Tissue Damage: Development of a Novel and Efficient Mouse Model of Clostridium difficile Toxin Exposure

(2012) Simon A. Hirota et al.   INFECTION AND IMMUNITY

TheClostridium difficile spo0AGene Is a Persistence and Transmission Factor

(2012) Laura J. Deakin et al.   INFECTION AND IMMUNITY

Suppression of Clostridium difficile in the Gastrointestinal Tracts of Germfree Mice Inoculated with a Murine Isolate from the Family Lachnospiraceae

(2012) Angela E. Reeves et al.   INFECTION AND IMMUNITY

Meeting the challenge of recurrent Clostridium difficile infection

(2012) Stuart Johnson   Journal of Hospital Medicine

Targeted Restoration of the Intestinal Microbiota with a Simple, Defined Bacteriotherapy Resolves Relapsing Clostridium difficile Disease in Mice

(2012) Trevor D. Lawley et al.   PLoS Pathogens

Mouse Relapse Model of Clostridium difficile Infection

(2011) Xingmin Sun et al.   INFECTION AND IMMUNITY

Profound Alterations of Intestinal Microbiota following a Single Dose of Clindamycin Results in Sustained Susceptibility to Clostridium difficile-Induced Colitis

(2011) Charlie G. Buffie et al.   INFECTION AND IMMUNITY

Infection of hamsters with the UK Clostridium difficile ribotype 027 outbreak strain R20291

(2011) A. M. Buckley et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Murine Model ofClostridium difficileInfection with Aged Gnotobiotic C57BL/6 Mice and a BI/NAP1 Strain

(2010) S. W. Pawlowski et al.   JOURNAL OF INFECTIOUS DISEASES

The role of toxin A and toxin B in Clostridium difficile infection

(2010) Sarah A. Kuehne et al.   NATURE

Variations in TcdB Activity and the Hypervirulence of Emerging Strains of Clostridium difficile

(2010) Jordi M. Lanis et al.   PLoS Pathogens

Distinctive Profiles of Infection and Pathology in Hamsters Infected with Clostridium difficile Strains 630 and B1

(2009) D. Goulding et al.   INFECTION AND IMMUNITY

Antibiotic Treatment of Clostridium difficile Carrier Mice Triggers a Supershedder State, Spore-Mediated Transmission, and Severe Disease in Immunocompromised Hosts

(2009) T. D. Lawley et al.   INFECTION AND IMMUNITY

Toxin B is essential for virulence of Clostridium difficile

(2009) Dena Lyras et al.   NATURE

Specific Microbiota Direct the Differentiation of IL-17-Producing T-Helper Cells in the Mucosa of the Small Intestine

(2008) Ivaylo I. Ivanov et al.   Cell Host & Microbe

A Mouse Model of Clostridium difficile–Associated Disease

(2008) Xinhua Chen et al.   GASTROENTEROLOGY

Clostridium difficile— More Difficult Than Ever

(2008) Ciarán P. Kelly et al.   NEW ENGLAND JOURNAL OF MEDICINE

Structure and mode of action of clostridial glucosylating toxins: the ABCD model

(2008) Thomas Jank et al.   TRENDS IN MICROBIOLOGY