Identification of the WNT1 residues required for palmitoylation by Porcupine

Disulfide Bond Requirements for Active Wnt Ligands

(2014) Bryan T. MacDonald et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Key Residues and Regions Important for Porcupine-mediated Wnt Acylation

(2014) Jessica Rios-Esteves et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Method for Cellular Imaging of Palmitoylated Proteins with Clickable Probes and Proximity Ligation Applied to Hedgehog, Tubulin, and Ras

(2014) Xinxin Gao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Porcn-dependent Wnt signaling is not required prior to mouse gastrulation

(2013) S. Biechele et al.   DEVELOPMENT

The apical and basolateral secretion of Wnt11 and Wnt3a in polarized epithelial cells is regulated by different mechanisms

(2013) H. Yamamoto et al.   JOURNAL OF CELL SCIENCE

Single-cell imaging of Wnt palmitoylation by the acyltransferase porcupine

(2013) Xinxin Gao et al.   Nature Chemical Biology

Stearoyl CoA Desaturase Is Required to Produce Active, Lipid-Modified Wnt Proteins

(2013) Jessica Rios-Esteves et al.   Cell Reports

Roles of N-glycosylation and lipidation in Wg secretion and signaling

(2012) Xiaofang Tang et al.   DEVELOPMENTAL BIOLOGY

Wnt3 function in the epiblast is required for the maintenance but not the initiation of gastrulation in mice

(2012) Giovane G. Tortelote et al.   DEVELOPMENTAL BIOLOGY

Identification of N-terminal Residues of Sonic Hedgehog Important for Palmitoylation by Hedgehog Acyltransferase

(2012) Rayshonda Y. Hardy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diverse Chemical Scaffolds Support Direct Inhibition of the Membrane-boundO-Acyltransferase Porcupine

(2012) Michael E. Dodge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis of Wnt Recognition by Frizzled

(2012) C. Y. Janda et al.   SCIENCE

Porcupine-mediated lipidation is required for Wnt recognition by Wls

(2011) Patrick Herr et al.   DEVELOPMENTAL BIOLOGY

Membrane targeting of palmitoylated Wnt and Hedgehog revealed by chemical probes

(2011) Xinxin Gao et al.   FEBS LETTERS

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Differential Palmit(e)oylation of Wnt1 on C93 and S224 Residues Has Overlapping and Distinct Consequences

(2011) Lisa M. Galli et al.   PLoS One

Deletion of mouse Porcn blocks Wnt ligand secretion and reveals an ectodermal etiology of human focal dermal hypoplasia/Goltz syndrome

(2011) J. J. Barrott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification

(2010) G. S. Coombs et al.   JOURNAL OF CELL SCIENCE

A new bioinformatics analysis tools framework at EMBL-EBI

(2010) M. Goujon et al.   NUCLEIC ACIDS RESEARCH

Wnt Trafficking: New Insights into Wnt Maturation, Secretion and Spreading

(2010) Fillip Port et al.   TRAFFIC

Imaging the Lipidome: ω-Alkynyl Fatty Acids for Detection and Cellular Visualization of Lipid-Modified Proteins

(2009) Rami N. Hannoush et al.   ACS Chemical Biology

Wnt11/5a Complex Formation Caused by Tyrosine Sulfation Increases Canonical Signaling Activity

(2009) Sang-Wook Cha et al.   CURRENT BIOLOGY

Towards an integrated view of Wnt signaling in development

(2009) R. van Amerongen et al.   DEVELOPMENT

PORCNmutations in focal dermal hypoplasia: coping with lethality

(2009) Dorothea Bornholdt et al.   HUMAN MUTATION

A Wnt Survival Guide: From Flies to Human Disease

(2009) Andy J. Chien et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Progress and challenges in understanding planar cell polarity signaling

(2009) Jeffrey D. Axelrod   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Wnt Signaling from Development to Disease: Insights from Model Systems

(2009) K. M. Cadigan et al.   Cold Spring Harbor Perspectives in Biology

Identification of the Acyltransferase that Octanoylates Ghrelin, an Appetite-Stimulating Peptide Hormone

(2008) Jing Yang et al.   CELL

Wnt Signaling in Development, Disease and Translational Medicine

(2008) Gary Coombs et al.   CURRENT DRUG TARGETS

Regulation of Wnt protein secretion and its role in gradient formation

(2008) Kerstin Bartscherer et al.   EMBO REPORTS

Acyl-CoA:Lysophospholipid Acyltransferases

(2008) Hideo Shindou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hhat Is a Palmitoylacyltransferase with Specificity forN-Palmitoylation of Sonic Hedgehog

(2008) John A. Buglino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery of a lysophospholipid acyltransferase family essential for membrane asymmetry and diversity

(2008) D. Hishikawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ghrelin octanoylation mediated by an orphan lipid transferase

(2008) J. A. Gutierrez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA