Construction of a genome-scale metabolic network of the plant pathogenPectobacterium carotovorumprovides new strategies for bactericide discovery

Shigellareroutes host cell central metabolism to obtain high-flux nutrient supply for vigorous intracellular growth

(2014) David Kentner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Basic and applied uses of genome-scale metabolic network reconstructions of Escherichia coli

(2013) D. McCloskey et al.   Molecular Systems Biology

Scientific workflow systems: Pipeline Pilot and KNIME

(2012) Wendy A. Warr   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Ferredoxin Containing Bacteriocins Suggest a Novel Mechanism of Iron Uptake in Pectobacterium spp

(2012) Rhys Grinter et al.   PLoS One

Quorum Sensing and Expression of Virulence in Pectobacteria

(2012) Lee Põllumaa et al.   SENSORS

Molecular evolution of urea amidolyase and urea carboxylase in fungi

(2011) Pooja K Strope et al.   BMC EVOLUTIONARY BIOLOGY

A community effort towards a knowledge-base and mathematical model of the human pathogen Salmonella Typhimurium LT2

(2011) Ines Thiele et al.   BMC Systems Biology

An Experimentally Validated Genome-Scale Metabolic Reconstruction of Klebsiella pneumoniae MGH 78578, iYL1228

(2011) Y.-C. Liao et al.   JOURNAL OF BACTERIOLOGY

A comprehensive genome-scale reconstruction of Escherichia coli metabolism--2011

(2011) J. D. Orth et al.   Molecular Systems Biology

Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0

(2011) Jan Schellenberger et al.   Nature Protocols

Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery

(2011) F. Zhu et al.   NUCLEIC ACIDS RESEARCH

The 3-Hydroxy-2-Butanone Pathway Is Required for Pectobacterium carotovorum Pathogenesis

(2011) Maria del Pilar Marquez-Villavicencio et al.   PLoS One

Structure and Function of the D-Galactose Network in Enterobacteria

(2011) Z. Csiszovszki et al.   mBio

Cytoscape 2.8: new features for data integration and network visualization

(2010) M. E. Smoot et al.   BIOINFORMATICS

Insight into human alveolar macrophage and M. tuberculosis interactions via metabolic reconstructions

(2010) Aarash Bordbar et al.   Molecular Systems Biology

High-throughput screening of tissue-nonspecific alkaline phosphatase for identification of effectors with diverse modes of action

(2010) Eduard A Sergienko et al.   Nature Protocols

BRENDA, the enzyme information system in 2011

(2010) M. Scheer et al.   NUCLEIC ACIDS RESEARCH

Genome Scale Reconstruction of a Salmonella Metabolic Model

(2009) Manal AbuOun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases

(2009) Ron Caspi et al.   NUCLEIC ACIDS RESEARCH

PubChem: a public information system for analyzing bioactivities of small molecules

(2009) Y. Wang et al.   NUCLEIC ACIDS RESEARCH

Why similar protein sequences encode similar three-dimensional structures?

(2009) Szymon Kaczanowski et al.   THEORETICAL CHEMISTRY ACCOUNTS

Medicinal Chemistry and the Molecular Operating Environment (MOE): Application of QSAR and Molecular Docking to Drug Discovery

(2008) Santiago Vilar et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Large-scale prediction of drug-target relationships

(2008) Michael Kuhn et al.   FEBS LETTERS

Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances

(2008) Irith Wiegand et al.   Nature Protocols