Formation of protein complexes in crowded environments - From in vitro to in vivo

Contrasting Factors on the Kinetic Path to Protein Complex Formation Diminish the Effects of Crowding Agents

(2012) Yael Phillip et al.   BIOPHYSICAL JOURNAL

Three-Dimensional Stochastic Off-Lattice Model of Binding Chemistry in Crowded Environments

(2012) Byoungkoo Lee et al.   PLoS One

Protein-binding dynamics imaged in a living cell

(2012) Y. Phillip et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macromolecular Crowding Extended to a Heptameric System: The Co-chaperonin Protein 10

(2011) Ximena Aguilar et al.   BIOCHEMISTRY

Protein Stability and Folding Kinetics in the Nucleus and Endoplasmic Reticulum of Eucaryotic Cells

(2011) A. Dhar et al.   BIOPHYSICAL JOURNAL

Effects of polydisperse crowders on aggregation reactions: A molecular thermodynamic analysis

(2011) Dhawal Shah et al.   JOURNAL OF CHEMICAL PHYSICS

Modest Protein−Crowder Attractive Interactions Can Counteract Enhancement of Protein Association by Intermolecular Excluded Volume Interactions

(2011) Jonathan Rosen et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Protein Crowding Tunes Protein Stability

(2011) Andrew C. Miklos et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Volume Exclusion and Soft Interaction Effects on Protein Stability under Crowded Conditions

(2010) Andrew C. Miklos et al.   BIOCHEMISTRY

Increase of SARS-CoV 3CL peptidase activity due to macromolecular crowding effects in the milieu composition

(2010) Debora N. Okamoto et al.   BIOLOGICAL CHEMISTRY

The Diffusion Coefficient for PGK Folding in Eukaryotic Cells

(2010) Apratim Dhar et al.   BIOPHYSICAL JOURNAL

Attractive Protein-Polymer Interactions Markedly Alter the Effect of Macromolecular Crowding on Protein Association Equilibria

(2010) Ming Jiao et al.   BIOPHYSICAL JOURNAL

Models of macromolecular crowding effects and the need for quantitative comparisons with experiment

(2010) Adrian H Elcock   CURRENT OPINION IN STRUCTURAL BIOLOGY

Crowding Effects on Protein Association: Effect of Interactions between Crowding Agents

(2010) Jun Soo Kim et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Crowding Effects on Amyloid Aggregation Kinetics

(2010) Andrea Magno et al.   Journal of Physical Chemistry Letters

Effects of Proteins on Protein Diffusion

(2010) Yaqiang Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Protein folding stability and dynamics imaged in a living cell

(2010) Simon Ebbinghaus et al.   NATURE METHODS

Diffusion, Crowding & Protein Stability in a Dynamic Molecular Model of the Bacterial Cytoplasm

(2010) Sean R. McGuffee et al.   PLoS Computational Biology

Common Crowding Agents Have Only a Small Effect on Protein-Protein Interactions

(2009) Yael Phillip et al.   BIOPHYSICAL JOURNAL

Effect of Macromolecular Crowding on Reaction Rates: A Computational and Theoretical Study

(2009) Jun Soo Kim et al.   BIOPHYSICAL JOURNAL

Determination of Dissociation Constants in Living Zebrafish Embryos with Single Wavelength Fluorescence Cross-Correlation Spectroscopy

(2009) Xianke Shi et al.   BIOPHYSICAL JOURNAL

Atomistic Modeling of Macromolecular Crowding Predicts Modest Increases in Protein Folding and Binding Stability

(2009) Sanbo Qin et al.   BIOPHYSICAL JOURNAL

Effect of Macromolecular Crowding on Protein Binding Stability: Modest Stabilization and Significant Biological Consequences

(2009) Jyotica Batra et al.   BIOPHYSICAL JOURNAL

Determination ofin VivoDissociation Constant,KD, of Cdc42-Effector Complexes in Live Mammalian Cells Using Single Wavelength Fluorescence Cross-correlation Spectroscopy

(2009) Thankiah Sudhaharan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-resolution multi-dimensional NMR spectroscopy of proteins in human cells

(2009) Kohsuke Inomata et al.   NATURE

Post-reductionist protein science, or putting Humpty Dumpty back together again

(2009) Lila M Gierasch et al.   Nature Chemical Biology

Nonadditive effects of mixed crowding on protein stability

(2009) Jyotica Batra et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Macromolecular Crowding and Confinement: Biochemical, Biophysical, and Potential Physiological Consequences

(2008) Huan-Xiang Zhou et al.   Annual Review of Biophysics

Crowding Effects on Diffusion in Solutions and Cells

(2008) James A. Dix et al.   Annual Review of Biophysics

Mixed macromolecular crowding inhibits amyloid formation of hen egg white lysozyme

(2008) Bing-Rui Zhou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Influence of Macromolecular Crowding on Protein-Protein Association Rates—a Brownian Dynamics Study

(2008) Grzegorz Wieczorek et al.   BIOPHYSICAL JOURNAL

Coarse-Grained Molecular Simulation of Diffusion and Reaction Kinetics in a Crowded Virtual Cytoplasm

(2008) Douglas Ridgway et al.   BIOPHYSICAL JOURNAL

NMR Spectroscopy Reveals Cytochromec–Poly(ethylene glycol) Interactions

(2008) Peter B. Crowley et al.   CHEMBIOCHEM

Stochastic off-lattice modeling of molecular self-assembly in crowded environments by Green’s function reaction dynamics

(2008) Byoungkoo Lee et al.   PHYSICAL REVIEW E

Protein self-association in crowded protein solutions: A time-resolved fluorescence polarization study

(2004) Silvia Zorrilla et al.   PROTEIN SCIENCE