The secreted oligomeric form of α-synuclein affects multiple steps of membrane trafficking

Antibody-Aided Clearance of Extracellular  -Synuclein Prevents Cell-to-Cell Aggregate Transmission

(2012) E.-J. Bae et al.   JOURNAL OF NEUROSCIENCE

Beyond α-synuclein transfer: pathology propagation in Parkinson's disease

(2012) Christian Hansen et al.   TRENDS IN MOLECULAR MEDICINE

α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells

(2011) Christian Hansen et al.   JOURNAL OF CLINICAL INVESTIGATION

Enzyme-linked immunosorbent assays for alpha-synuclein with species and multimeric state specificities

(2011) He-Jin Lee et al.   JOURNAL OF NEUROSCIENCE METHODS

Mechanism of Membrane Interaction and Disruption by α-Synuclein

(2011) Nicholas P. Reynolds et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pathological roles of α-synuclein in neurological disorders

(2011) Kostas Vekrellis et al.   LANCET NEUROLOGY

Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death

(2011) Laura A. Volpicelli-Daley et al.   NEURON

Overexpression of Dyrk1A Causes the Defects in Synaptic Vesicle Endocytosis

(2011) Yoonju Kim et al.   NEUROSIGNALS

In Vivo RNAi Screen Reveals Neddylation Genes as Novel Regulators of Hedgehog Signaling

(2011) Juan Du et al.   PLoS One

Small GTPase Rab12 Regulates Constitutive Degradation of Transferrin Receptor

(2011) Takahide Matsui et al.   TRAFFIC

Synthesis of potent chemical inhibitors of dynamin GTPase

(2010) Suho Lee et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Membrane Curvature Induction and Tubulation Are Common Features of Synucleins and Apolipoproteins

(2010) Jobin Varkey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SNX18 shares a redundant role with SNX9 and modulates endocytic trafficking at the plasma membrane

(2010) J. Park et al.   JOURNAL OF CELL SCIENCE

Cell-Produced  -Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival

(2010) E. Emmanouilidou et al.   JOURNAL OF NEUROSCIENCE

Cell-to-cell transmission of non-prion protein aggregates

(2010) Seung-Jae Lee et al.   Nature Reviews Neurology

Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis

(2010) Venu M. Nemani et al.   NEURON

On the mechanism of internalization of α-synuclein into microglia: roles of ganglioside GM1 and lipid raft

(2009) Ji-Young Park et al.   JOURNAL OF NEUROCHEMISTRY

Dissecting the potential molecular mechanisms underlying α-synuclein cell-to-cell transfer in Parkinson's disease

(2009) Elodie Angot et al.   PARKINSONISM & RELATED DISORDERS

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of  -synuclein

(2009) P. Desplats et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assembly-dependent endocytosis and clearance of extracellular a-synuclein

(2008) He-Jin Lee et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Role of Alpha-Synuclein in Neurodegenerative Diseases: A Potential Target for New Treatment Strategies?

(2008) M. Windisch et al.   Neurodegenerative Diseases

Membrane Trafficking: Intracellular Highways and Country Roads

(2008) A. Y. Cheung et al.   PLANT PHYSIOLOGY

α-Synuclein and Polyunsaturated Fatty Acids Promote Clathrin-Mediated Endocytosis and Synaptic Vesicle Recycling

(2008) Tziona Ben Gedalya et al.   TRAFFIC