Protein translocation as a tool: The current rapamycin story

Protein Tango: The Toolbox to Capture Interacting Partners

(2012) Anna Rutkowska et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

No-Wash Protein Labeling with Designed Fluorogenic Probes and Application to Real-Time Pulse-Chase Analysis

(2012) Shin Mizukami et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rapid and orthogonal logic gating with a gibberellin-induced dimerization system

(2012) Takafumi Miyamoto et al.   Nature Chemical Biology

Direct Monitoring of the Inhibition of Protein-Protein Interactions in Cells by Translocation of PKCδ Fusion Proteins

(2011) Kyung-Bok Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Switching Heterotrimeric G Protein Subunits with a Chemical Dimerizer

(2011) Mateusz Putyrski et al.   CHEMISTRY & BIOLOGY

Intracellular Protein Labeling with Prodrug-Like Probes Using a Mutant β-Lactamase Tag

(2011) Shuji Watanabe et al.   CHEMISTRY-A EUROPEAN JOURNAL

Small-molecule displacement of a cryptic degron causes conditional protein degradation

(2011) Kimberly M Bonger et al.   Nature Chemical Biology

Triggering Actin Comets Versus Membrane Ruffles: Distinctive Effects of Phosphoinositides on Actin Reorganization

(2011) T. Ueno et al.   Science Signaling

Engineering the ABA Plant Stress Pathway for Regulation of Induced Proximity

(2011) F.-S. Liang et al.   Science Signaling

Chemically Controlled Protein Assembly: Techniques and Applications

(2010) Adrian Fegan et al.   CHEMICAL REVIEWS

Synthetic Strategies for Studying Embryonic Development

(2010) Xiaohu Ouyang et al.   CHEMISTRY & BIOLOGY

Rapid Inactivation of Proteins by Rapamycin-Induced Rerouting to Mitochondria

(2010) Margaret S. Robinson et al.   DEVELOPMENTAL CELL

Chemical Inducers of Targeted Protein Degradation

(2010) Kanak Raina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Constitutive Cargo Transport from thetrans-Golgi Network to Plasma Membrane by Golgi-localized G Protein βγ Subunits

(2010) Roshanak Irannejad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics

(2010) Fubito Nakatsu et al.   JOURNAL OF CELL BIOLOGY

A Photocleavable Rapamycin Conjugate for Spatiotemporal Control of Small GTPase Activity

(2010) Nobuhiro Umeda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Light Regulation of Protein Dimerization and Kinase Activity in Living Cells Using Photocaged Rapamycin and Engineered FKBP

(2010) Andrei V. Karginov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Engineered allosteric activation of kinases in living cells

(2010) Andrei V Karginov et al.   NATURE BIOTECHNOLOGY

Organelle-specific, rapid induction of molecular activities and membrane tethering

(2010) Toru Komatsu et al.   NATURE METHODS

Conditionally controlling nuclear trafficking in yeast by chemical-induced protein dimerization

(2010) Tao Xu et al.   Nature Protocols

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Physical Association of PDK1 with AKT1 Is Sufficient for Pathway Activation Independent of Membrane Localization and Phosphatidylinositol 3 Kinase

(2010) Zhiyong Ding et al.   PLoS One

Acute manipulation of Golgi phosphoinositides to assess their importance in cellular trafficking and signaling

(2010) Z. Szentpetery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of STIM1-Orai1 Involves an Intramolecular Switching Mechanism

(2010) M. K. Korzeniowski et al.   Science Signaling

Role of phosphoinositides in STIM1 dynamics and store-operated calcium entry

(2009) Ciara M. Walsh et al.   BIOCHEMICAL JOURNAL

A Phosphoinositide Switch Controls the Maturation and Signaling Properties of APPL Endosomes

(2009) Roberto Zoncu et al.   CELL

Conditional Nuclear Import and Export of Yeast Proteins Using a Chemical Inducer of Dimerization

(2009) Srikanth Patury et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Membrane-Permeant Phosphoinositide Derivatives as Modulators of Growth Factor Signaling and Neurite Outgrowth

(2009) Vibor Laketa et al.   CHEMISTRY & BIOLOGY

Dependence of STIM1/Orai1-mediated Calcium Entry on Plasma Membrane Phosphoinositides

(2009) Marek K. Korzeniowski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective Cross-Linking of Interacting Proteins Using Self-Labeling Tags

(2009) Arnaud Gautier et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantification of Nuclear Protein Transport using Induced Heterodimerization

(2009) Albert Busch et al.   TRAFFIC

Interaction with Phosphoinositides Confers Adaptation onto the TRPV1 Pain Receptor

(2009) Jing Yao et al.   PLOS BIOLOGY

Rapid Activation of Akt2 Is Sufficient to Stimulate GLUT4 Translocation in 3T3-L1 Adipocytes

(2008) Yvonne Ng et al.   Cell Metabolism

Robust Neuronal Symmetry Breaking by Ras-Triggered Local Positive Feedback

(2008) Marc Fivaz et al.   CURRENT BIOLOGY

Dissecting the role of PtdIns(4,5)P2 in endocytosis and recycling of the transferrin receptor

(2008) N. Abe et al.   JOURNAL OF CELL SCIENCE

The Anchor-Away Technique: Rapid, Conditional Establishment of Yeast Mutant Phenotypes

(2008) Hirohito Haruki et al.   MOLECULAR CELL

Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation

(2008) Riina M. Luik et al.   NATURE

Chemical control of protein stability and function in living mice

(2008) Laura A Banaszynski et al.   NATURE MEDICINE

Synthetic Activation of Endogenous PI3K and Rac Identifies an AND-Gate Switch for Cell Polarization and Migration

(2008) Takanari Inoue et al.   PLoS One

A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN

(2008) M. Rahdar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A small molecule-directed approach to control protein localization and function

(2008) Prasanthi Geda et al.   YEAST