Engineered riboswitches: Expanding researchers' toolbox with synthetic RNA regulators

Mechanistic Basis for RNA Aptamer-Based Induction of TetR

(2011) Markus Steber et al.   CHEMBIOCHEM

Selection of tetracycline inducible self-cleaving ribozymes as synthetic devices for gene regulation in yeast

(2011) Alexander Wittmann et al.   Molecular BioSystems

Conformational dynamics of the tetracycline-binding aptamer

(2011) Ute Förster et al.   NUCLEIC ACIDS RESEARCH

Rational design of a small molecule-responsive intramer controlling transgene expression in mammalian cells

(2011) David Ausländer et al.   NUCLEIC ACIDS RESEARCH

Highly Modular Structure and Ligand Binding by Conformational Capture in a Minimalistic Riboswitch

(2010) Elke Duchardt-Ferner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthetic Riboswitches That Induce Gene Expression in Diverse Bacterial Species

(2010) S. Topp et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

PELDOR Spectroscopy Reveals Preorganization of the Neomycin-Responsive Riboswitch Tertiary Structure

(2010) Ivan Krstić et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A ligand-dependent hammerhead ribozyme switch for controlling mammalian gene expression

(2010) Simon Ausländer et al.   Molecular BioSystems

Automation in the High-throughput Selection of Random Combinatorial Libraries—Different Approaches for Select Applications

(2010) Jörn Glökler et al.   MOLECULES

Functional roles for noise in genetic circuits

(2010) Avigdor Eldar et al.   NATURE

Reprogramming bacteria to seek and destroy an herbicide

(2010) Joy Sinha et al.   Nature Chemical Biology

Synthetic biology: applications come of age

(2010) Ahmad S. Khalil et al.   NATURE REVIEWS GENETICS

Mechanistic insights into an engineered riboswitch: a switching element which confers riboswitch activity

(2010) Julia E. Weigand et al.   NUCLEIC ACIDS RESEARCH

Genetic control of mammalian T-cell proliferation with synthetic RNA regulatory systems

(2010) Y. Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ligand-induced conformational capture of a synthetic tetracycline riboswitch revealed by pulse EPR

(2010) D. Wunnicke et al.   RNA

The Structural and Functional Diversity of Metabolite-Binding Riboswitches

(2009) Adam Roth et al.   Annual Review of Biochemistry

Ligand-induced sequestering of branchpoint sequence allows conditional control of splicing

(2009) Dong-Suk Kim et al.   BMC MOLECULAR BIOLOGY

An RNA Aptamer that Induces Transcription

(2009) Anke Hunsicker et al.   CHEMISTRY & BIOLOGY

A fast and efficient translational control system for conditional expression of yeast genes

(2009) Peter Kötter et al.   NUCLEIC ACIDS RESEARCH

Micromagnetic selection of aptamers in microfluidic channels

(2009) X. Lou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct selection for ribozyme cleavage activity in cells

(2009) X. Chen et al.   RNA

Improved Aptazyme Design and In Vivo Screening Enable Riboswitching in Bacteria

(2008) Markus Wieland et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences

(2008) Arjun Raj et al.   CELL

Artificial Riboswitches: Synthetic mRNA-Based Regulators of Gene Expression

(2008) Markus Wieland et al.   CHEMBIOCHEM

A FACS-Based Approach to Engineering Artificial Riboswitches

(2008) Casey C. Fowler et al.   CHEMBIOCHEM

Structural Basis for Specific, High-Affinity Tetracycline Binding by an In Vitro Evolved Aptamer and Artificial Riboswitch

(2008) Hong Xiao et al.   CHEMISTRY & BIOLOGY

Mining logic gates in prokaryotic transcriptional regulation networks

(2008) Rafael Silva-Rocha et al.   FEBS LETTERS

Engineering Complex Riboswitch Regulation by Dual Genetic Selection

(2008) Vandana Sharma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A flow cytometry-based screen for synthetic riboswitches

(2008) Sean A. Lynch et al.   NUCLEIC ACIDS RESEARCH

S-box and T-box riboswitches and antisense RNA control a sulfur metabolic operon of Clostridium acetobutylicum

(2008) Gaëlle André et al.   NUCLEIC ACIDS RESEARCH

Uncovering cis Regulatory Codes Using Synthetic Promoter Shuffling

(2008) Ali Kinkhabwala et al.   PLoS One

Random Walks to Synthetic Riboswitches—A High-Throughput Selection Based on Cell Motility

(2007) Shana Topp et al.   CHEMBIOCHEM