Two sides of the story? Smad4 loss in pancreatic cancer versus head-and-neck cancer

Meta-analysis of immunohistochemical prognostic markers in resected pancreatic cancer

(2011) R A Smith et al.   BRITISH JOURNAL OF CANCER

Expression and clinical significance of the transforming growth factor-β signalling pathway in endometrial cancer

(2011) Paulette Mhawech-Fauceglia et al.   HISTOPATHOLOGY

Smad2 Protein Disruption in the Central Nervous System Leads to Aberrant Cerebellar Development and Early Postnatal Ataxia in Mice

(2011) Lixiang Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Smad4 deficiency in T cells leads to the Th17-associated development of premalignant gastroduodenal lesions in mice

(2011) Jennifer Nancy Hahn et al.   JOURNAL OF CLINICAL INVESTIGATION

SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression

(2011) Zhihu Ding et al.   NATURE

Mutations at a single codon in Mad homology 2 domain of SMAD4 cause Myhre syndrome

(2011) Carine Le Goff et al.   NATURE GENETICS

Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis

(2011) Ingrid M B H van de Laar et al.   NATURE GENETICS

Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1

(2011) N. Agrawal et al.   SCIENCE

Oncogenic Smad3 signaling induced by chronic inflammation is an early event in ulcerative colitis-associated carcinogenesis

(2010) Seiji Kawamata et al.   INFLAMMATORY BOWEL DISEASES

Smad2 Positively Regulates the Generation of Th17 Cells

(2010) Gustavo J. Martinez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SMAD2 Is Essential for TGFβ-mediated Th17 Cell Generation

(2010) Nidhi Malhotra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HGF upregulation contributes to angiogenesis in mice with keratinocyte-specific Smad2 deletion

(2010) Kristina E. Hoot et al.   JOURNAL OF CLINICAL INVESTIGATION

Smad2 Protects against TGF- /Smad3-Mediated Renal Fibrosis

(2010) X. M. Meng et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Susceptibility Pathways in Fanconi's Anemia and Breast Cancer

(2010) Alan D. D'Andrea   NEW ENGLAND JOURNAL OF MEDICINE

Genetic evidence that SMAD2 is not required for gonadal tumor development in inhibin-deficient mice

(2010) Saneal Rajanahally et al.   Reproductive Biology and Endocrinology

Epidermal Smad4 Deletion Results in Aberrant Wound Healing

(2009) Philip Owens et al.   AMERICAN JOURNAL OF PATHOLOGY

Cancer Statistics, 2009

(2009) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

SMAD4 Gene Mutations Are Associated with Poor Prognosis in Pancreatic Cancer

(2009) A. Blackford et al.   CLINICAL CANCER RESEARCH

DPC4 Gene Status of the Primary Carcinoma Correlates With Patterns of Failure in Patients With Pancreatic Cancer

(2009) Christine A. Iacobuzio-Donahue et al.   JOURNAL OF CLINICAL ONCOLOGY

Acceleration of Palatal Wound Healing in Smad3-deficient Mice

(2009) K. Jinno et al.   JOURNAL OF DENTAL RESEARCH

Molecular Basis of Colorectal Cancer

(2009) Sanford D. Markowitz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Synergistic action of Smad4 and Pten in suppressing pancreatic ductal adenocarcinoma formation in mice

(2009) X Xu et al.   ONCOGENE

Cancer-Associated Transforming Growth Factor   Type II Receptor Gene Mutant Causes Activation of Bone Morphogenic Protein-Smads and Invasive Phenotype

(2008) S. Bharathy et al.   CANCER RESEARCH

Non-Smad pathways in TGF-β signaling

(2008) Ying E Zhang   CELL RESEARCH

Smad3 knockout mice exhibit impaired intestinal mucosal healing

(2008) Cheri R Owen et al.   LABORATORY INVESTIGATION

Growth inhibition induced by transforming growth factor-β1 in human oral squamous cell carcinoma

(2008) Xiumei Wang et al.   MOLECULAR BIOLOGY REPORTS

Tumor suppressor and oncogene actions of TGFβ1 occur early in skin carcinogenesis and are mediated by Smad3

(2008) Dong-Soon Bae et al.   MOLECULAR CARCINOGENESIS

Promoter methylation correlates with reduced Smad4 expression in advanced prostate cancer

(2008) Alan A. Aitchison et al.   PROSTATE