Familial hypertrophic cardiomyopathy related E180G mutation increases flexibility of human cardiac α-tropomyosin

Persistence Length of Human Cardiac α-Tropomyosin Measured by Single Molecule Direct Probe Microscopy

(2012) Campion K. P. Loong et al.   PLoS One

Filament Compliance Influences Cooperative Activation of Thin Filaments and the Dynamics of Force Production in Skeletal Muscle

(2012) Bertrand C. W. Tanner et al.   PLoS Computational Biology

Tropomyosin Flexural Rigidity and Single Ca2+ Regulatory Unit Dynamics: Implications for Cooperative Regulation of Cardiac Muscle Contraction and Cardiomyocyte Hypertrophy

(2012) Campion K. P. Loong et al.   Frontiers in Physiology

Several cardiomyopathy causing mutations on tropomyosin either destabilize the active state of actomyosin or alter the binding properties of tropomyosin

(2011) Mohit C. Mathur et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Flexibility Change in Human Cardiac α-Tropomyosin E180G Mutant: Possible Link to Cardiac Hypertrophy

(2011) Campion Loong et al.   BIOPHYSICAL JOURNAL

Enhanced Active Cross-Bridges during Diastole: Molecular Pathogenesis of Tropomyosin's HCM Mutations

(2011) Fan Bai et al.   BIOPHYSICAL JOURNAL

Thin Filament Mutations

(2011) Jil C. Tardiff   CIRCULATION RESEARCH

Facilitated Cross-Bridge Interactions with Thin Filaments by Familial Hypertrophic Cardiomyopathy Mutations inα-Tropomyosin

(2011) Fang Wang et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Multi-scale computational models of familial hypertrophic cardiomyopathy: genotype to phenotype

(2011) S. G. Campbell et al.   Journal of the Royal Society Interface

Echocardiographic Strain Imaging to Assess Early and Late Consequences of Sarcomere Mutations in Hypertrophic Cardiomyopathy

(2009) Carolyn Y. Ho et al.   Circulation-Cardiovascular Genetics

Mutations in Troponin that cause HCM, DCM AND RCM: What can we learn about thin filament function?

(2009) Ruth H. Willott et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY