Simple, realistic models of complex biological processes: Positive feedback and bistability in a cell fate switch and a cell cycle oscillator

Digital Signaling and Hysteresis Characterize Ras Activation in Lymphoid Cells

(2009) Jayajit Das et al.   CELL

Irreversibility of mitotic exit is the consequence of systems-level feedback

(2009) Sandra López-Avilés et al.   NATURE

Molecular Origin and Functional Consequences of Digital Signaling and Hysteresis During Ras Activation in Lymphocytes

(2009) A. K. Chakraborty et al.   Science Signaling

Positive feedback sharpens the anaphase switch

(2008) Liam J. Holt et al.   NATURE

Positive feedback of G1 cyclins ensures coherent cell cycle entry

(2008) Jan M. Skotheim et al.   NATURE

Robust, Tunable Biological Oscillations from Interlinked Positive and Negative Feedback Loops

(2008) T. Y.-C. Tsai et al.   SCIENCE