Article
Chemistry, Physical
Gagandeep Kaur, Vishaldeep Kaur, Navneet Kaur, Charanleen Kaur, Kritika Sood, Asifkhan Shanavas, Tapasi Sen
Summary: A multifunctional core-shell nanostructure of silicon oxide@noble metal was synthesized and demonstrated to have dual applications in SERS enhancement and photothermal annihilation of breast cancer cells.
Article
Chemistry, Multidisciplinary
Jun Hou, Yanbao Zhao, Lei Sun, Xueyan Zou
Summary: Gold nanomaterials with surface features have gained significant interest in cancer research. In this study, gold nanostar carriers coated with mesoporous silica were developed for controlled drug release and showed photothermal-chemo therapeutic effect.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2022)
Article
Engineering, Environmental
Qipeng Xie, Honglai Lu, Xiaoli Wang, Yuting Zhang, Nandi Zhou
Summary: A dual-functional smart material was developed for bacterial detection and sterilization using electrostatic interaction between Rhodamine B-loaded amino-modified hollow mesoporous silica spheres and Staphylococcus aureus-specific aptamer-modified gold nanorods. This material shows specific detection and photothermal sterilization functions, with the potential to help save resources and reduce antibiotic abuse.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Chemistry, Analytical
Jaime Quinones, Fabiola Carolina Miranda-Castro, David Encinas-Basurto, Jaime Ibarra, Edgar Felipe Moran-Palacio, Luis Alberto Zamora-Alvarez, Mario Almada
Summary: The encapsulation and release of cisplatin using a mesoporous silica-coated gold nanorods system is reported in this study. Gold nanorods were synthesized using an acidic seed-mediated method and then coated with silica using a modified Stober method. The silica shell was modified with carboxylates groups to improve cisplatin encapsulation. Cisplatin was efficiently encapsulated under optimal conditions and released in a controlled manner, with faster release at acidic pH compared to neutral pH.
Article
Chemistry, Multidisciplinary
Jessi E. S. van der Hoeven, Harith Gurunarayanan, Maarten Bransen, D. A. Matthijs de Winter, Petra E. de Jongh, Alfons van Blaaderen
Summary: The study introduces a new type of functional assembly called supraparticles, which are formed by the solvent-driven assembly of silica-coated gold nanorods into spherical ensembles. The plasmonic coupling and mass transport are controlled by adjusting the thickness and porosity of the silica shells. These novel materials have the potential to play an important role in sensing applications.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Physics, Applied
Cheng-ping Huang, Xiao-gang Yin
Summary: This study developed an analytical model for metallic nanorods, considering the longitudinally non-uniform conduction current and surface charges, in order to provide a formula for the resonance wavelength of the fundamental longitudinal mode that agrees well with simulations. By introducing radiative resistance to circuit theory, the dipole moment, extinction spectrum, and near-field enhancement of the nanorod were analytically derived and numerically confirmed. These results are significant for understanding the optical properties of metallic nanorods and guiding the design of light scattering and absorption.
JOURNAL OF APPLIED PHYSICS
(2022)
Article
Chemistry, Multidisciplinary
Chun Shan, Yuting Huang, Junhao Wei, Min Chen, Limin Wu
Summary: In this work, gold nanorods embedded in ultra-thick silica shells with radial mesopores (AuNR/R-SiO2) were successfully synthesized in an ethanol/water solution. The AuNR/R-SiO2 exhibited ultra-high thermal stability and outstanding loading capacity, making them promising for drug delivery and tumor therapy. Controlled release behavior via near-infrared (NIR) laser was achieved, and in vitro experiments showed biocompatibility and ease of internalization by cells.
Article
Chemistry, Multidisciplinary
Yongfeng Tian, Lu Zhao, Yonghua Pan, Zhengfeng Li, Xiaofeng Shen, Xia Zhang, Xianghu Tang, Xin Feng, Xingjiu Huang
Summary: Surface enhanced Raman spectroscopy (SERS) was used to evaluate the volatile release of nicotine from snus products under different storage conditions. By comparing the intensities of the spectral peaks of nicotine molecules with increasing temperature and humidity, the nicotine release under different conditions could be evaluated. This study provides valuable reference for understanding the volatile release of nicotine and regulating its levels in snus products, and opens up new perspectives for further research on the impact of nicotinoids on smokers' health and cessation programs.
Article
Chemistry, Analytical
Yun-Xiao Zhao, Wei-Wei Zhu, Ye-Yu Wu, Yu-Yun Chen, Fang-Kai Du, Jun Yan, Xue-Cai Tan, Qi Wang
Summary: A rapid and sensitive quantitative detection method for formaldehyde based on surface-enhanced Raman scattering (SERS) using gold nanorods (GNRs) has been developed in this study. The method takes advantage of the enhanced function of GNRs to reduce the detection limit of formaldehyde, offering simplicity, rapid performance, and cost effectiveness.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Supriya Atta, Vo-Dinh Tuan
Summary: This study presents a cost-effective and highly reproducible SERS platform utilizing a portable Raman instrument for fast sensitive detection of illegal drugs in human urine. The platform combines the SERS enhancement properties of BGNS-Ag and the advantages of NaI salt for SERS signal amplification. The platform shows ultra-high sensitivity with a LOD as low as 10 pg/mL for cocaine and 100 pg/mL for heroin.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Multidisciplinary
Caterina Dallari, Claudia Capitini, Martino Calamai, Andrea Trabocchi, Francesco Saverio Pavone, Caterina Credi
Summary: Gold nanoparticles have unique physicochemical and optical functionalities that make them ideal for spectroscopy-based detection techniques, particularly for SERS. By conjugating different moieties to the nanoparticles, their plasmonic properties can be combined with the specific recognition capabilities of antibodies for analysis of biological fluids in clinical settings.
Article
Nanoscience & Nanotechnology
Jayakumar Pillanagrovi, Shourya Dutta-Gupta
Summary: This study presents a strategy to assemble gold nanoparticles in resonant gold nanoapertures for coupling-mediated near-field enhancement. The assembled AuNP-NA substrates showed improved SERS potential compared to bare NA templates, and numerical simulations indicated the importance of coupling between plasmonic modes for this enhancement.
Article
Food Science & Technology
Min-Hui Lin, Lin Sun, Fanbin Kong, Mengshi Lin
Summary: This study established a novel, facile, and rapid testing technique using surface-enhanced Raman spectroscopy (SERS) coupled with gold nanostars as a SERS substrate to detect pesticide residues in green tea. The spiky tips of gold nanostars acted as SERS hot spots to enhance Raman signals, while the rough topography increased surface area for better substrate-analyte interactions. The SERS method showed great potential for qualification and quantification of trace contaminants in foods with a detection limit of 0.2 mg/kg for paraquat in green tea samples.
Article
Nanoscience & Nanotechnology
Nhat M. Ngo, Hung-Vu Tran, T. Randall Lee
Summary: The emergence of plasmonic nanostars has enabled a wide range of advanced technologies with great potential. Their superior surface-to-volume ratios and intensely amplified electric fields make them ideal for various applications. However, further study and development are still needed due to the nascency of this unique class of nanostructures.
ACS APPLIED NANO MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Gregory Barbillon, Christophe Humbert, Maria Ujue Gonzalez, Jose Miguel Garcia-Martin
Summary: In this study, we investigated chemical sensing using surface-enhanced Raman scattering with gold nanocolumn templates. The glancing angle deposition with magnetron sputtering technique was chosen for its low-cost production and ease of implementation. The fabricated gold nanocolumnar structures allowed for the production of a high density of strongly confined electric field spots. The vertical and tilted nanocolumnar templates showed promising results for the detection and adsorption of thiophenol molecules.
Review
Chemistry, Multidisciplinary
Jesus Mosquera, Da Wang, Sara Bals, Luis M. Liz-Marzan
Summary: Gold nanorods (Au NRs) are highly promising tools in nanotechnology due to their strong interaction with electromagnetic radiation, tunable resonance frequency, and easy preparation. Surfactants play a critical role in controlling the size, shape, and stability of Au NRs, but the interaction between Au NRs and surfactants is not well understood. This article reviews the current knowledge on these interactions and explores methods for synthesizing and modifying Au NRs.
ACCOUNTS OF CHEMICAL RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Uwe Frank, Dominik Drobek, Ana Sanchez-Iglesias, Simon E. Wawra, Nico Nees, Johannes Walter, Lukas Pflug, Benjamin Apeleo Zubiri, Erdmann Spiecker, Luis M. Liz-Marzan, Wolfgang Peukert
Summary: Multidimensional particle properties are crucial in determining the product properties in advanced applications. Accurate and statistically meaningful measurements of complex particles and their distributions are highly challenging but necessary. A workflow for calculating frictional properties of arbitrarily shaped nanoparticles was developed and applied to gold bipyramids, showing good agreement with transmission electron microscopy measurements except for a slight shift caused by differences in assumed and real particle shape and composition.
Review
Chemistry, Multidisciplinary
Leonardo Scarabelli, Muhua Sun, Xiaolu Zhuo, Sungjae Yoo, Jill E. Millstone, Matthew R. Jones, Luis M. Liz-Marzan
Summary: In this review, recent progress in the solution-phase growth of colloidal plate-like metal nanoparticles, including plasmonic and other metals, is summarized. Mechanistic insights for different synthetic strategies, the crystallographic habits of different metals, and the use of nanoplates as scaffolds for the synthesis of other derivative structures are emphasized. Representative self-assembly techniques and the attractive properties and unique versatility of the 2D morphology are highlighted. Existing challenges and future perspectives for plate-like metal nanomaterials are also discussed.
Article
Chemistry, Physical
Safiyye Kavak, Ajinkya Anil Kadu, Nathalie Claes, Ana Sanchez-Iglesias, Luis M. Liz-Marzan, Kees Joost Batenburg, Sara Bals
Summary: In this study, a method for automating the volumetric segmentation process applied to three-dimensional reconstructions of nanoparticle assemblies is proposed. The performance of different automated segmentation methods in accurately extracting quantitative descriptors for morphological characterization is evaluated. The results show that the spherical Hough transform exhibits superior performance in accurately extracting quantitative descriptors, allowing for an objective, efficient, and reliable volumetric segmentation of complex nanoparticle assemblies.
JOURNAL OF PHYSICAL CHEMISTRY C
(2023)
Article
Chemistry, Multidisciplinary
Jack L. Eatson, Jacob R. Gordon, Piotr Cegielski, Anna L. Giesecke, Stephan Suckow, Anish Rao, Oscar F. Silvestre, Luis M. Liz-Marzan, Tommy S. Horozov, D. Martin A. Buzza
Summary: The unique behavior of colloids at liquid interfaces provides exciting opportunities for engineering the assembly of colloidal particles into functional materials. The deformable nature of fluid-fluid interfaces enables the utilization of interfacial curvature to direct self-assembly. The study utilizes a finite element method to investigate the self-assembly of rod-shaped particles adsorbed at a curved fluid-fluid interface. The findings demonstrate that the curved interface effectively controls the orientation of the rods and allows for the manipulation of single and multiple rod-like particles for the organization of functional materials.
Article
Chemistry, Multidisciplinary
Javier Plou, Pablo S. Valera, Isabel Garcia, David Vila-Liarte, Carlos Renero-Lecuna, Jesus Ruiz-Cabello, Arkaitz Carracedo, Luis M. Liz-Marzan
Summary: During the response to stress, damaged cells release metabolites and secretomes, which can be utilized in anticancer therapies and biomarker predictions. However, monitoring these processes is challenging, leading to the development of noninvasive secretome screening tools. Machine learning methods and microfluidic chips were used to identify secretome variations and classify cell death, allowing for faster implementation of surface-enhanced Raman scattering (SERS) into cell secretome classification.
Article
Materials Science, Multidisciplinary
Manuel Obelleiro-Liz, Victor F. Martin, Diego M. Solis, Jose M. Taboada, Fernando Obelleiro, Luis M. Liz-Marzan
Summary: Chiral metal nanoparticles can induce and harness optical activity, but there is limited control over their morphological detail and resulting optical activity due to incomplete knowledge of growth mechanisms. This study uses computer-aided design and simulations to analyze the influence of structural changes on the plasmonic circular dichroism spectra of rod-shaped gold nanoparticles. Interesting patterns in plasmon-mediated resonant behavior are identified, which can guide the understanding and fabrication of these nanoparticles for applications such as spectroscopic detection and surface-enhanced Raman optical activity.
ADVANCED OPTICAL MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Evgenii Vlasov, Alexander Skorikov, Ana Sanchez-Iglesias, Luis M. Liz-Marzan, Johan Verbeeck, Sara Bals
Summary: Electron tomography (ET) is a powerful tool for determining the 3D structure of nanomaterials, but it is time-consuming. Surface-sensitive secondary electron (SE) imaging, using the SE electron beam induced current (SEEBIC) technique, is proposed as an alternative to ET for studying nanomaterial morphology. SEEBIC imaging provides valuable information with high spatial resolution and shorter throughput times compared to ET. The contrast formation mechanisms that aid in interpreting SEEBIC data are also discussed.
ACS MATERIALS LETTERS
(2023)
Editorial Material
Chemistry, Multidisciplinary
Warren C. W. Chan, Natalie Artzi, Chunying Chen, Xiaodong Chen, Dean Ho, Tony Hu, Kazunori Kataoka, Luis M. Liz-Marzan, Rahmi Oklu, Wolfgang J. Parak
Article
Chemistry, Physical
Xiaolu Zhuo, David Vila-Liarte, Shengyan Wang, Dorleta Jimenez de Aberasturi, Luis M. Liz-Marzan
Summary: A study on the stability of chiral gold nanorods (Au NRs) covered by different protecting shells was conducted. The findings can be applied to other chiral plasmonic nanoparticles and address concerns of instability in various applications.
CHEMISTRY OF MATERIALS
(2023)
Editorial Material
Chemistry, Physical
Galo J. A. A. Soler-Illia, Marco Faustini, Luis M. Liz-Marzan
CHEMISTRY OF MATERIALS
(2023)
Article
Chemistry, Physical
Jiaoyang Sa, Ningneng Hu, Wouter Heyvaert, Kyle Van Gordon, Hao Li, Le Wang, Sara Bals, Luis M. Liz-Marzan, Weihai Ni
Summary: Chiral ligands are necessary for the synthesis of dissymmetric plasmonic metal nanocrystals. However, chirality can also spontaneously evolve during the co-deposition of Au and Ag on Au nanorods. The presence of a specific Au/Ag ratio leads to phase segregation, forming an interface within the AuAg shell. Chirality is observed both at the Au-Ag interface and at the exposed surface of Au nanorods after Ag etching.
CHEMISTRY OF MATERIALS
(2023)
Review
Chemistry, Multidisciplinary
Ben Tadgell, Luis M. Liz-Marzan
Summary: Chiral plasmonic nanoparticles interact with biomolecules in distinct ways and can be probed using circular dichroism spectroscopy, offering potential advantages in biosensing and biomedical applications.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Kyle Van Gordon, Sandra Baulde, Mikhail Mychinko, Wouter Heyvaert, Manuel Obelleiro-Liz, Alejandro Criado, Sara Bals, Luis M. Liz-Marzan, Jesus Mosquera
Summary: The concentration of the chiral inducer can control the chiral morphology and chiroptical properties of gold nanomaterials, offering potential for advancements in biosensing and nano-optics.
Article
Chemistry, Multidisciplinary
Carla Estevez-Varela, Sara Nunez-Sanchez, Paula Pineiro-Varela, Dorleta Jimenez de Aberasturi, Luis M. Liz-Marzan, Jorge Perez-Juste, Isabel Pastoriza-Santos
Summary: Plexcitonic nanoparticles, which exhibit strong light-matter interactions, have been investigated using UV-visible and SERS spectroscopies, supported by FDTD calculations in this study. The combination of plasmonic nanomaterials and J-aggregates is found to be crucial, with the refractive index contrast between water and the TDBC shell playing a significant role in the observed SERS efficiency.
