Metabolic states with maximal specific rate carry flux through an elementary flux mode

How Biochemical Constraints of Cellular Growth Shape Evolutionary Adaptations in Metabolism

(2013) J. Berkhout et al.   GENETICS

Availability of public goods shapes the evolution of competing metabolic strategies

(2013) H. Bachmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic shifts: a fitness perspective for microbial cell factories

(2012) Anisha Goel et al.   BIOTECHNOLOGY LETTERS

Multidimensional Optimality of Microbial Metabolism

(2012) R. Schuetz et al.   SCIENCE

Cost-Benefit Tradeoffs in Engineered lac Operons

(2012) M. Eames et al.   SCIENCE

Optimal flux spaces of genome-scale stoichiometric models are determined by a few subnetworks

(2012) Steven M. Kelk et al.   Scientific Reports

Combining Metabolic Pathway Analysis with Evolutionary Game Theory. Explaining the occurrence of low-yield pathways by an analytic optimization approach

(2011) Stefan Schuster et al.   BIOSYSTEMS

Genome-Scale Metabolic Modeling Elucidates the Role of Proliferative Adaptation in Causing the Warburg Effect

(2011) Tomer Shlomi et al.   PLoS Computational Biology

Catabolic efficiency of aerobic glycolysis: The Warburg effect revisited

(2010) Alexei Vazquez et al.   BMC Systems Biology

Functional roles for noise in genetic circuits

(2010) Avigdor Eldar et al.   NATURE

What is flux balance analysis?

(2010) Jeffrey D Orth et al.   NATURE BIOTECHNOLOGY

Shifts in growth strategies reflect tradeoffs in cellular economics

(2009) Douwe Molenaar et al.   Molecular Systems Biology

Large-scale computation of elementary flux modes with bit pattern trees

(2008) Marco Terzer et al.   BIOINFORMATICS

The Cost of Expression of Escherichia coli lac Operon Proteins Is in the Process, Not in the Products

(2008) D. M. Stoebel et al.   GENETICS

Is maximization of molar yield in metabolic networks favoured by evolution?

(2007) Stefan Schuster et al.   JOURNAL OF THEORETICAL BIOLOGY