Dissecting the contribution of thrombin exosite I in the recognition of thrombin binding aptamer

Duplex–quadruplex motifs in a peculiar structural organization cooperatively contribute to thrombin binding of a DNA aptamer

(2013) Irene Russo Krauss et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

An Overview of Biological Macromolecule Crystallization

(2013) Irene Russo Krauss et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antidote Control of Aptamer Therapeutics: The Road to a Safer Class of Drug Agents

(2012) K. M. Bompiani et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Thrombin Binding Aptamer, More than a Simple Aptamer: Chemically Modified Derivatives and Biomedical Applications

(2012) Anna Avino et al.   CURRENT PHARMACEUTICAL DESIGN

Investigating the Role of T7 and T12 Residues on the Biological Properties of Thrombin-Binding Aptamer: Enhancement of Anticoagulant Activity by a Single Nucleobase Modification

(2012) Nicola Borbone et al.   JOURNAL OF MEDICINAL CHEMISTRY

Interaction of water with the G-quadruplex loop contributes to the binding energy of G-quadruplex to protein

(2012) Satoru Nagatoishi et al.   Molecular BioSystems

High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity

(2012) Irene Russo Krauss et al.   NUCLEIC ACIDS RESEARCH

Polyvalent nucleic acid aptamers and modulation of their activity: a focus on the thrombin binding aptamer

(2012) Domenica Musumeci et al.   PHARMACOLOGY & THERAPEUTICS

Rational Design and Characterization of D-Phe-Pro-D-Arg-Derived Direct Thrombin Inhibitors

(2012) Ana C. Figueiredo et al.   PLoS One

Loop residues of thrombin-binding DNA aptamer impact G-quadruplex stability and thrombin binding

(2011) Satoru Nagatoishi et al.   BIOCHIMIE

Molecular Imaging with Nucleic Acid Aptamers

(2011) H. Hong et al.   CURRENT MEDICINAL CHEMISTRY

Thrombin–aptamer recognition: a revealed ambiguity

(2011) Irene Russo Krauss et al.   NUCLEIC ACIDS RESEARCH

Molecular aptamers for drug delivery

(2011) Weihong Tan et al.   TRENDS IN BIOTECHNOLOGY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Crystallization and preliminary X-ray analysis of the complex of human α-thrombin with a modified thrombin-binding aptamer

(2010) Irene Russo Krauss et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Development of aptamer therapeutics

(2010) David HJ Bunka et al.   CURRENT OPINION IN PHARMACOLOGY

Aptamers as therapeutics

(2010) Anthony D. Keefe et al.   NATURE REVIEWS DRUG DISCOVERY

Structural and thermodynamic analysis of thrombin:suramin interaction in solution and crystal phases

(2009) Luis Maurício T.R. Lima et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Effect of Locked-Nucleic Acid on a Biologically Active G-Quadruplex. A Structure-Activity Relationship of the Thrombin Aptamer

(2008) Laura Bonifacio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles

(2008) S. Dhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA