标题
The potential of histone deacetylase inhibitors in Niemann - Pick type C disease
作者
关键词
-
出版物
FEBS Journal
Volume 280, Issue 24, Pages 6367-6372
出版商
Wiley
发表日期
2013-08-31
DOI
10.1111/febs.12505
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Discovery of Oxysterol-Derived Pharmacological Chaperones for NPC1: Implication for the Existence of Second Sterol-Binding Site
- (2013) Kenji Ohgane et al. CHEMISTRY & BIOLOGY
- Identification of Niemann-Pick C1 disease biomarkers through sphingolipid profiling
- (2013) Martin Fan et al. JOURNAL OF LIPID RESEARCH
- Cyclodextrin mediates rapid changes in lipid balance inNpc1−/−mice without carrying cholesterol through the bloodstream
- (2012) Anna M. Taylor et al. JOURNAL OF LIPID RESEARCH
- Miglustat Improves Purkinje Cell Survival and Alters Microglial Phenotype in Feline Niemann-Pick Disease Type C
- (2012) Veronika M. Stein et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Effects of cyclodextrin in two patients with Niemann–Pick Type C disease
- (2012) Muneaki Matsuo et al. MOLECULAR GENETICS AND METABOLISM
- Structure, mechanism, and inhibition of histone deacetylases and related metalloenzymes
- (2011) Patrick M Lombardi et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- An “Exacerbate-reverse” Strategy in Yeast Identifies Histone Deacetylase Inhibition as a Correction for Cholesterol and Sphingolipid Transport Defects in Human Niemann-Pick Type C Disease
- (2011) Andrew B. Munkacsi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ebola virus entry requires the cholesterol transporter Niemann–Pick C1
- (2011) Jan E. Carette et al. NATURE
- Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts
- (2011) N. H. Pipalia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Amino acid substitution in NPC1 that abolishes cholesterol binding reproduces phenotype of complete NPC1 deficiency in mice
- (2011) X. Xie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Niemann-Pick type C 1 function requires lumenal domain residues that mediate cholesterol-dependent NPC2 binding
- (2011) M. S. Deffieu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of Surface Residues on Niemann-Pick C2 Essential for Hydrophobic Handoff of Cholesterol to NPC1 in Lysosomes
- (2010) Michael L. Wang et al. Cell Metabolism
- Endocytosis of beta-cyclodextrins is responsible for cholesterol reduction in Niemann-Pick type C mutant cells
- (2010) A. I. Rosenbaum et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cholesterol Oxidation Products Are Sensitive and Specific Blood-Based Biomarkers for Niemann-Pick C1 Disease
- (2010) F. D. Porter et al. Science Translational Medicine
- Lipids on Trial: The Search for the Offending Metabolite in Niemann-Pick type C Disease
- (2010) Emyr Lloyd-Evans et al. TRAFFIC
- Targeting the correct HDAC(s) to treat cognitive disorders
- (2010) André Fischer et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol
- (2009) Hyock Joo Kwon et al. CELL
- Recommendations on the diagnosis and management of Niemann-Pick disease type C
- (2009) James E. Wraith et al. MOLECULAR GENETICS AND METABOLISM
- Miglustat in adult and juvenile patients with Niemann–Pick disease type C: Long-term data from a clinical trial
- (2009) James E. Wraith et al. MOLECULAR GENETICS AND METABOLISM
- Chronic Cyclodextrin Treatment of Murine Niemann-Pick C Disease Ameliorates Neuronal Cholesterol and Glycosphingolipid Storage and Disease Progression
- (2009) Cristin D. Davidson et al. PLoS One
- Reversal of defective lysosomal transport in NPC disease ameliorates liver dysfunction and neurodegeneration in the npc1-/- mouse
- (2009) B. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate
- (2009) N. C. Hait et al. SCIENCE
- Niemann-Pick Type C1 I1061T Mutant Encodes a Functional Protein That Is Selected for Endoplasmic Reticulum-associated Degradation Due to Protein Misfolding
- (2008) Mark E. Gelsthorpe et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium
- (2008) Emyr Lloyd-Evans et al. NATURE MEDICINE
- Therapeutic application of histone deacetylase inhibitors for central nervous system disorders
- (2008) Aleksey G. Kazantsev et al. NATURE REVIEWS DRUG DISCOVERY
- The many roles of histone deacetylases in development and physiology: implications for disease and therapy
- (2008) Michael Haberland et al. NATURE REVIEWS GENETICS
- NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes
- (2008) R. E. Infante et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now