A surprising observation that oxygen can affect the product enantiopurity of an enzyme-catalysed reaction

Distant and New Mutations in CTX-M-1 β-Lactamase Affect Cefotaxime Hydrolysis

(2011) Francisco José Pérez-Llarena et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Site-Saturated Mutagenesis Study of Pentaerythritol Tetranitrate Reductase Reveals that Residues 181 and 184 Influence Ligand Binding, Stereochemistry and Reactivity

(2011) Helen S. Toogood et al.   CHEMBIOCHEM

Active site modifications in pentaerythritol tetranitrate reductase can lead to improved product enantiopurity, decreased by-product formation and altered stereochemical outcome in reactions with α,β-unsaturated nitroolefins

(2011) Anna Fryszkowska et al.   Catalysis Science & Technology

The Substrate Spectra of Pentaerythritol Tetranitrate Reductase, Morphinone Reductase,N-Ethylmaleimide Reductase and Estrogen-Binding Protein in the Asymmetric Bioreduction of Activated Alkenes

(2010) Nicole J. Mueller et al.   ADVANCED SYNTHESIS & CATALYSIS

Focused Directed Evolution of Pentaerythritol Tetranitrate Reductase by Using Automated Anaerobic Kinetic Screening of Site-Saturated Libraries

(2010) Martyn E. Hulley et al.   CHEMBIOCHEM

Biocatalytic Reductions and Chemical Versatility of the Old Yellow Enzyme Family of Flavoprotein Oxidoreductases

(2010) Helen S. Toogood et al.   ChemCatChem

The flavoprotein-catalyzed reduction of aliphatic nitro-compounds represents a biocatalytic equivalent to the Nef-reaction

(2010) Katharina Durchschein et al.   GREEN CHEMISTRY

Asymmetric Reduction of Activated Alkenes by Pentaerythritol Tetranitrate Reductase: Specificity and Control of Stereochemical Outcome by Reaction Optimisation

(2009) Anna Fryszkowska et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Bioreduction of CC Bonds using Enoate Reductases OPR1, OPR3 and YqjM: Enzyme-Based Stereocontrol

(2008) Mélanie Hall et al.   ADVANCED SYNTHESIS & CATALYSIS

Structure-Based Insight into the Asymmetric Bioreduction of the CC Double Bond of α,β-Unsaturated Nitroalkenes by Pentaerythritol Tetranitrate Reductase

(2008) Helen S. Toogood et al.   ADVANCED SYNTHESIS & CATALYSIS

Expanding the functional diversity of proteins through cysteine oxidation

(2008) Khalilah G Reddie et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Highly Enantioselective Reduction of β,β-Disubstituted Aromatic Nitroalkenes Catalyzed byClostridium sporogenes

(2008) Anna Fryszkowska et al.   JOURNAL OF ORGANIC CHEMISTRY