Human butyrylcholinesterase produced in insect cells: huprine-based affinity purification and crystal structure

Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents

(2012) Guillaume Mercey et al.   ACCOUNTS OF CHEMICAL RESEARCH

First efficient uncharged reactivators for the dephosphylation of poisoned human acetylcholinesterase

(2011) Guillaume Mercey et al.   CHEMICAL COMMUNICATIONS

New Huprine Derivatives Functionalized at Position 9 as Highly Potent Acetylcholinesterase Inhibitors

(2011) Cyril Ronco et al.   ChemMedChem

Huprine Derivatives as Sub-Nanomolar Human Acetylcholinesterase Inhibitors: From Rational Design to Validation by X-ray Crystallography

(2011) Cyril Ronco et al.   ChemMedChem

Evolution of and perspectives on therapeutic approaches to nerve agent poisoning

(2011) Patrick Masson   TOXICOLOGY LETTERS

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

X-ray crystallographic snapshots of reaction intermediates in the G117H mutant of human butyrylcholinesterase, a nerve agent target engineered into a catalytic bioscavenger

(2010) Florian Nachon et al.   BIOCHEMICAL JOURNAL

Aging mechanism of butyrylcholinesterase inhibited by an N-methyl analogue of tabun: Implications of the trigonal–bipyramidal transition state rearrangement for the phosphylation or reactivation of cholinesterases

(2010) Florian Nachon et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Structural approach to the aging of phosphylated cholinesterases

(2010) Patrick Masson et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Acetylcholinesterase: From 3D structure to function

(2010) Hay Dvir et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Effect of sialic acid content on glycoprotein pI analyzed by two-dimensional electrophoresis

(2010) Sílvia Barrabés et al.   ELECTROPHORESIS

Structural insights into the exquisite selectivity of neurexin/neuroligin synaptic interactions

(2010) Philippe Leone et al.   EMBO JOURNAL

Design, Preparation, and Characterization of High-Activity Mutants of Human Butyrylcholinesterase Specific for Detoxification of Cocaine

(2010) L. Xue et al.   MOLECULAR PHARMACOLOGY

Transgenic plants as a source for the bioscavenging enzyme, human butyrylcholinesterase

(2010) Brian C. Geyer et al.   PLANT BIOTECHNOLOGY JOURNAL

Pilot-scale production of human serum butyrylcholinesterase suitable for use as a bioscavenger against nerve agent toxicity

(2010) Ashima Saxena et al.   PROCESS BIOCHEMISTRY

Synthesis and structure–activity relationship of Huprine derivatives as human acetylcholinesterase inhibitors

(2009) Cyril Ronco et al.   BIOORGANIC & MEDICINAL CHEMISTRY