Docking proteins

Analysis of DOK-6 function in downstream signaling of RET in human neuroblastoma cells

(2010) Ai Kurotsuchi et al.   CANCER SCIENCE

Dok-7 promotes slow muscle integrity as well as neuromuscular junction formation in a zebrafish model of congenital myasthenic syndromes

(2010) Juliane S. Müller et al.   HUMAN MOLECULAR GENETICS

Overexpression of the oncogenic signal transducer Gab2 occurs early in breast cancer development

(2010) Emmy D.G. Fleuren et al.   INTERNATIONAL JOURNAL OF CANCER

The Gab1 scaffold regulates RTK-dependent dorsal ruffle formation through the adaptor Nck

(2010) J. V. Abella et al.   JOURNAL OF CELL SCIENCE

Identification of DOK genes as lung tumor suppressors

(2010) Alice H Berger et al.   NATURE GENETICS

Gab2-Mediated Signaling Promotes Melanoma Metastasis

(2009) Basil Horst et al.   AMERICAN JOURNAL OF PATHOLOGY

Expression and function of the insulin receptor substrate proteins in cancer

(2009) Katerina Mardilovich et al.   Cell Communication and Signaling

Function, regulation and pathological roles of the Gab/DOS docking proteins

(2009) Franziska U Wöhrle et al.   Cell Communication and Signaling

GAB2 Amplifications Refine Molecular Classification of Melanoma

(2009) K. A. Chernoff et al.   CLINICAL CANCER RESEARCH

Regulation of lymphocyte development and activation by the LAT family of adapter proteins

(2009) Deirdre M. Fuller et al.   IMMUNOLOGICAL REVIEWS

The roles of Dok family adapters in immunoreceptor signaling

(2009) Ryuichi Mashima et al.   IMMUNOLOGICAL REVIEWS

Dok-4 Is a Novel Negative Regulator of T Cell Activation

(2009) A. Gerard et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Dok-1 and Dok-2 Adaptor Molecules Are Regulated by Phosphatidylinositol 5-Phosphate Production in T Cells

(2009) G. Guittard et al.   JOURNAL OF IMMUNOLOGY

Phenotype genotype analysis in 15 patients presenting a congenital myasthenic syndrome due to mutations in DOK7

(2009) A. Ben Ammar et al.   JOURNAL OF NEUROLOGY

Differential phosphorylation of the docking protein Gab1 by c-Src and the hepatocyte growth factor receptor regulates different aspects of cell functions

(2009) P-C Chan et al.   ONCOGENE

Focal amplification and oncogene dependency of GAB2 in breast cancer

(2009) M Bocanegra et al.   ONCOGENE

Constitutive plasma membrane targeting and microdomain localization of Dok5 studied by single-molecule microscopy

(2008) Guo Fu et al.   BIOPHYSICAL CHEMISTRY

Regulation of growth factor signaling by FRS2 family docking/scaffold adaptor proteins

(2008) Noriko Gotoh   CANCER SCIENCE

Protein Kinase C Function in Muscle, Liver, and  -Cells and Its Therapeutic Implications for Type 2 Diabetes

(2008) C. Schmitz-Peiffer et al.   DIABETES

Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein

(2008) Tilman Brummer et al.   EMBO JOURNAL

Protein Kinase C-ζ Phosphorylates Insulin Receptor Substrate-1, -3, and -4 But Not -2: Isoform Specific Determinants of Specificity in Insulin Signaling

(2008) Sihoon Lee et al.   ENDOCRINOLOGY

Differential membrane compartmentalization of Ret by PTB-adaptor engagement

(2008) T. K. Lundgren et al.   FEBS Journal

Amplification of 11q13 in ovarian carcinoma

(2008) Lindsay A. Brown et al.   GENES CHROMOSOMES & CANCER

Deletion of Shp2 Tyrosine Phosphatase in Muscle Leads to Dilated Cardiomyopathy, Insulin Resistance, and Premature Death

(2008) F. Princen et al.   MOLECULAR AND CELLULAR BIOLOGY

A Different View on DNA Amplifications Indicates Frequent, Highly Complex, and Stable Amplicons on 12q13-21 in Glioma

(2008) U. Fischer et al.   MOLECULAR CANCER RESEARCH

The CUL7 E3 Ubiquitin Ligase Targets Insulin Receptor Substrate 1 for Ubiquitin-Dependent Degradation

(2008) Xinsong Xu et al.   MOLECULAR CELL

Dok1 mediates high-fat diet–induced adipocyte hypertrophy and obesity through modulation of PPAR-γ phosphorylation

(2008) Tetsuya Hosooka et al.   NATURE MEDICINE

Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2

(2008) Jinhua Wu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Characterization of the 12q amplicons by high-resolution, oligonucleotide array CGH and expression analyses of a novel liposarcoma cell line

(2007) Fredrik Persson et al.   CANCER LETTERS