Is there more to aging than mitochondrial DNA and reactive oxygen species?

The Role of Mitochondria in Reactive Oxygen Species Metabolism and Signaling

(2010) Anatoly A. Starkov   Annals of the New York Academy of Sciences

Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 2. Treatment of some ROS- and Age-related diseases (heart arrhythmia, heart infarctions, kidney ischemia, and stroke)

(2009) L. E. Bakeeva et al.   BIOCHEMISTRY-MOSCOW

Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 4. Age-related eye disease. SkQ1 returns vision to blind animals

(2009) V. V. Neroev et al.   BIOCHEMISTRY-MOSCOW

Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 3. Inhibitory effect of SkQ1 on tumor development from p53-deficient cells

(2009) L. S. Agapova et al.   BIOCHEMISTRY-MOSCOW

Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 5. SkQ1 prolongs lifespan and prevents development of traits of senescence

(2009) V. N. Anisimov et al.   BIOCHEMISTRY-MOSCOW

Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 1. Cationic plastoquinone derivatives: Synthesis and in vitro studies

(2009) Y. N. Antonenko et al.   BIOCHEMISTRY-MOSCOW

Sarcopenia of aging: Underlying cellular mechanisms and protection by calorie restriction

(2009) Emanuele Marzetti et al.   BIOFACTORS

Novel DNA mismatch-repair activity involving YB-1 in human mitochondria

(2009) Nadja C. de Souza-Pinto et al.   DNA REPAIR

The mitochondrial theory of aging: Insight from transgenic and knockout mouse models

(2009) Youngmok C. Jang et al.   EXPERIMENTAL GERONTOLOGY

Mitochondrial functional complementation in mitochondrial DNA-based diseases

(2009) Kazuto Nakada et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Number matters: control of mammalian mitochondrial DNA copy number

(2009) Laura L. Clay Montier et al.   Journal of Genetics and Genomics

Current Thoughts on the Role of Mitochondria and Free Radicals in the Biology of Aging

(2009) H. Van Remmen et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Oxidative stress induces degradation of mitochondrial DNA

(2009) Inna Shokolenko et al.   NUCLEIC ACIDS RESEARCH

Deletion of the Mitochondrial Superoxide Dismutase sod-2 Extends Lifespan in Caenorhabditis elegans

(2009) Jeremy M. Van Raamsdonk et al.   PLoS Genetics

High rates of superoxide production in skeletal-muscle mitochondria respiring on both complex I- and complex II-linked substrates

(2008) Florian L. Muller et al.   BIOCHEMICAL JOURNAL

An attempt to prevent senescence: A mitochondrial approach

(2008) Vladimir P. Skulachev et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Angiotensin II Reduces Mitochondrial Content in Skeletal Muscle and Affects Glycemic Control

(2008) M. Mitsuishi et al.   DIABETES

Mitochondrial base excision repair of uracil and AP sites takes place by single-nucleotide insertion and long-patch DNA synthesis

(2008) Mansour Akbari et al.   DNA REPAIR

Modulation of longevity and diapause by redox regulation mechanisms under the insulin-like signaling control in Caenorhabditis elegans

(2008) Yoko Honda et al.   EXPERIMENTAL GERONTOLOGY

Glutathione peroxidase family - an evolutionary overview

(2008) Rogerio Margis et al.   FEBS Journal

Selective elimination of mutant mitochondrial genomes as therapeutic strategy for the treatment of NARP and MILS syndromes

(2008) M F Alexeyev et al.   GENE THERAPY

Mitochondrial Polymorphisms Are Associated Both with Increased and Decreased Longevity

(2008) Loredana Castri et al.   HUMAN HEREDITY

A functionally dominant mitochondrial DNA mutation

(2008) S. Sacconi et al.   HUMAN MOLECULAR GENETICS

Long Patch Base Excision Repair in Mammalian Mitochondrial Genomes

(2008) Bartosz Szczesny et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of a potent antioxidant, platinum nanoparticle, on the lifespan of Caenorhabditis elegans

(2008) Juewon Kim et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Removal of Oxidative DNA Damage via FEN1-Dependent Long-Patch Base Excision Repair in Human Cell Mitochondria

(2008) P. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

Generation of ρ 0 cells utilizing a mitochondrially targeted restriction endonuclease and comparative analyses

(2008) Alexandra Kukat et al.   NUCLEIC ACIDS RESEARCH

Mitochondrial DNA Haplogroup D4a Is a Marker for Extreme Longevity in Japan

(2008) Erhan Bilal et al.   PLoS One