BACE1 and presenilin/γ-secretase regulate proteolytic processing of KCNE1 and 2, auxiliary subunits of voltage-gated potassium channels

Inhibitory Interneuron Deficit Links Altered Network Activity and Cognitive Dysfunction in Alzheimer Model

(2012) Laure Verret et al.   CELL

β-Site APP-cleaving enzyme 1 (BACE1) cleaves cerebellar Na+ channel β4-subunit and promotes Purkinje cell firing by slowing the decay of resurgent Na+ current

(2011) Tobias Huth et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Reduced Sodium Channel Nav1.1 Levels in BACE1-null Mice

(2010) Doo Yeon Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BACE1 Deficiency Causes Altered Neuronal Activity and Neurodegeneration

(2010) X. Hu et al.   JOURNAL OF NEUROSCIENCE

Alzheimer's secretases regulate voltage-gated sodium channels

(2010) Dora M. Kovacs et al.   NEUROSCIENCE LETTERS

Ancillary Subunits Associated With Voltage-Dependent K+ Channels

(2010) Olaf Pongs et al.   PHYSIOLOGICAL REVIEWS

Variations in the neuropathology of familial Alzheimer’s disease

(2009) Claire Shepherd et al.   ACTA NEUROPATHOLOGICA

Regulation of the Kv2.1 Potassium Channel by MinK and MiRP1

(2009) Zoe A. McCrossan et al.   JOURNAL OF MEMBRANE BIOLOGY

The  -Secretase Enzyme BACE in Health and Alzheimer's Disease: Regulation, Cell Biology, Function, and Therapeutic Potential

(2009) R. Vassar et al.   JOURNAL OF NEUROSCIENCE

Epileptic Seizures in AD Patients

(2009) A. J. Larner   NEUROMOLECULAR MEDICINE

KCNE1 and KCNE3 β-Subunits Regulate Membrane Surface Expression of Kv12.2 K+ Channels In Vitro and Form a Tripartite Complex In Vivo

(2009) Sinead M. Clancy et al.   PLoS One

γ-Secretase Inhibition and Modulation for Alzheimers Disease

(2008) Michael Wolfe   Current Alzheimer Research

Non-proteolytic effect of β-site APP-cleaving enzyme 1 (BACE1) on sodium channel function

(2008) Tobias Huth et al.   NEUROBIOLOGY OF DISEASE

Phosphorylation of the Translation Initiation Factor eIF2α Increases BACE1 Levels and Promotes Amyloidogenesis

(2008) Tracy O'Connor et al.   NEURON