Host gene targets for novel influenza therapies elucidated by high-throughput RNA interference screens

Influenza: The Once and Future Pandemic

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Modifications in Small Interfering RNA That Separate Immunostimulation from RNA Interference

(2014) F. Eberle et al.   JOURNAL OF IMMUNOLOGY

Extending pathways and processes using molecular interaction networks to analyse cancer genome data

(2011) Enrico Glaab et al.   BMC BIOINFORMATICS

Innate immune response to influenza virus

(2011) Shuhua Wu et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Mosquito RNAi is the major innate immune pathway controlling arbovirus infection and transmission

(2011) Carol D Blair   Future Microbiology

Expression of Herpes Simplex Virus 1-Encoded MicroRNAs in Human Trigeminal Ganglia and Their Relation to Local T-Cell Infiltrates

(2011) K. Held et al.   JOURNAL OF VIROLOGY

Analysis of HIV-1 Expression Level and Sense of Transcription by High-Throughput Sequencing of the Infected Cell

(2011) G. Lefebvre et al.   JOURNAL OF VIROLOGY

Human Cytomegalovirus US7 Is Regulated Synergistically by Two Virally Encoded MicroRNAs and by Two Distinct Mechanisms

(2011) R. Tirabassi et al.   JOURNAL OF VIROLOGY

Recombinant Adenovirus Serotype 26 (Ad26) and Ad35 Vaccine Vectors Bypass Immunity to Ad5 and Protect Nonhuman Primates against Ebolavirus Challenge

(2011) T. W. Geisbert et al.   JOURNAL OF VIROLOGY

Visual Genome-Wide RNAi Screening to Identify Human Host Factors Required for Trypanosoma cruzi Infection

(2011) Auguste Genovesio et al.   PLoS One

Proteomic Analysis Shows Synthetic Oleanane Triterpenoid Binds to mTOR

(2011) Mark M. Yore et al.   PLoS One

High-Content Chemical and RNAi Screens for Suppressors of Neurotoxicity in a Huntington's Disease Model

(2011) Joost Schulte et al.   PLoS One

Analysis of EGFR signaling pathway in nasopharyngeal carcinoma cells by quantitative phosphoproteomics

(2011) Lin Ruan et al.   Proteome Science

Genome-wide analysis of primary CD4+ and CD8+ T cell transcriptomes shows evidence for a network of enriched pathways associated with HIV disease

(2011) Jing Wu et al.   Retrovirology

Proteomic and Functional Genomic Landscape of Receptor Tyrosine Kinase and Ras to Extracellular Signal-Regulated Kinase Signaling

(2011) A. A. Friedman et al.   Science Signaling

Increase in viral yield in eggs and MDCK cells of reassortant H5N1 vaccine candidate viruses caused by insertion of 38 amino acids into the NA stalk

(2011) Wenjun Zhang et al.   VACCINE

Influenza virus assembly and budding

(2011) Jeremy S. Rossman et al.   VIROLOGY

Lysosome-associated membrane glycoprotein 3 is involved in influenza A virus replication in human lung epithelial (A549) cells

(2011) Zhuo Zhou et al.   Virology Journal

Significant Effects of Antiretroviral Therapy on Global Gene Expression in Brain Tissues of Patients with HIV-1-Associated Neurocognitive Disorders

(2011) Alejandra Borjabad et al.   PLoS Pathogens

Comprehensive analysis of human microRNA target networks

(2011) Jun-ichi Satoh et al.   BioData Mining

Vigilance and Validation: Keys to Success in RNAi Screening

(2010) Frederic D. Sigoillot et al.   ACS Chemical Biology

The use of RNAi-based screens to identify host proteins involved in viral replication

(2010) Alec J Hirsch   Future Microbiology

mRNA deep sequencing reveals 75 new genes and a complex transcriptional landscape in Mimivirus

(2010) M. Legendre et al.   GENOME RESEARCH

The Rab11 Pathway Is Required for Influenza A Virus Budding and Filament Formation

(2010) E. A. Bruce et al.   JOURNAL OF VIROLOGY

Identifying HIV-1 host cell factors by genome-scale RNAi screening

(2010) Lars Pache et al.   METHODS

Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication

(2010) Alexander Karlas et al.   NATURE

Combined agonist-antagonist genome-wide functional screening identifies broadly active antiviral microRNAs

(2010) D. Santhakumar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Simultaneous high-resolution analysis of vaccinia virus and host cell transcriptomes by deep RNA sequencing

(2010) Z. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Epidermal Growth Factor Receptor (EGFR) Promotes Uptake of Influenza A Viruses (IAV) into Host Cells

(2010) Thorsten Eierhoff et al.   PLoS Pathogens

Biogenesis and function of endogenous and exogenous siRNAs

(2010) Nicholas M. Snead et al.   Wiley Interdisciplinary Reviews-RNA

Knowledge based identification of essential signaling from genome-scale siRNA experiments

(2009) Armand Bankhead et al.   BMC Systems Biology

A Physical and Regulatory Map of Host-Influenza Interactions Reveals Pathways in H1N1 Infection

(2009) Sagi D. Shapira et al.   CELL

The IFITM Proteins Mediate Cellular Resistance to Influenza A H1N1 Virus, West Nile Virus, and Dengue Virus

(2009) Abraham L. Brass et al.   CELL

Influenza virus M2 protein inhibits epithelial sodium channels by increasing reactive oxygen species

(2009) Ahmed Lazrak et al.   FASEB JOURNAL

Visual Integration of Quantitative Proteomic Data, Pathways, and Protein Interactions

(2009) Radu Jianu et al.   IEEE TRANSACTIONS ON VISUALIZATION AND COMPUTER GRAPHICS

Simulating Henipavirus Multicycle Replication in a Screening Assay Leads to Identification of a Promising Candidate for Therapy

(2009) M. Porotto et al.   JOURNAL OF VIROLOGY

Human host factors required for influenza virus replication

(2009) Renate König et al.   NATURE

Navigating the network: signaling cross-talk in hematopoietic cells

(2009) Iain D C Fraser et al.   NATURE IMMUNOLOGY

Statistical methods for analysis of high-throughput RNA interference screens

(2009) Amanda Birmingham et al.   NATURE METHODS

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Enhancement of the Influenza A Hemagglutinin (HA)-Mediated Cell-Cell Fusion and Virus Entry by the Viral Neuraminidase (NA)

(2009) Bin Su et al.   PLoS One

Minimum Information About a Microarray Experiment (MIAME) – Successes, Failures, Challenges

(2009) Alvis Brazma   TheScientificWorldJOURNAL

Modulation of influenza virus replication by alteration of sodium ion transport and protein kinase C activity

(2008) H HOFFMANN et al.   ANTIVIRAL RESEARCH

RNA viruses and the mitogenic Raf/MEK/ERK signal transduction cascade

(2008) Stephan Pleschka   BIOLOGICAL CHEMISTRY

A genome-wide shRNA screen identifies GAS1 as a novel melanoma metastasis suppressor gene

(2008) S. Gobeil et al.   GENES & DEVELOPMENT

The multifunctional NS1 protein of influenza A viruses

(2008) B. G. Hale et al.   JOURNAL OF GENERAL VIROLOGY

RNA Interference Inhibits Respiratory Syncytial Virus Replication and Disease Pathogenesis without Inhibiting Priming of the Memory Immune Response

(2008) W. Zhang et al.   JOURNAL OF VIROLOGY

NF- B Signaling Differentially Regulates Influenza Virus RNA Synthesis

(2008) N. Kumar et al.   JOURNAL OF VIROLOGY

Hepatitis C virus infection protein network

(2008) B de Chassey et al.   Molecular Systems Biology

Drosophila RNAi screen identifies host genes important for influenza virus replication

(2008) Linhui Hao et al.   NATURE

Apoptosis leads to a degradation of vital components of active nuclear transport and a dissociation of the nuclear lamina

(2008) A. Kramer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Host factors for replication and transcription of the influenza virus genome

(2008) Kyosuke Nagata et al.   REVIEWS IN MEDICAL VIROLOGY

Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen

(2008) Abraham L. Brass et al.   SCIENCE