Response of chondrocytes to shear stress: antagonistic effects of the binding partners Toll-like receptor 4 and caveolin-1

Prostaglandin E2 induces interleukin-6 expression in human chondrocytes via cAMP/protein kinase A- and phosphatidylinositol 3-kinase-dependent NF-κB activation

(2010) Pu Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the “reverse Warburg effect”: A transcriptional informatics analysis with validation

(2010) Stephanos Pavlides et al.   CELL CYCLE

Prostaglandin (PG)D2 and 15-deoxy-Δ12,14-PGJ2, but not PGE2, mediate shear-induced chondrocyte apoptosis via protein kinase A-dependent regulation of polo-like kinases

(2010) F Zhu et al.   CELL DEATH AND DIFFERENTIATION

Shear-induced Interleukin-6 Synthesis in Chondrocytes

(2010) Pu Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide expression profiling reveals new candidate genes associated with osteoarthritis

(2010) C. Karlsson et al.   OSTEOARTHRITIS AND CARTILAGE

Prolonged Application of High Fluid Shear to Chondrocytes Recapitulates Gene Expression Profiles Associated with Osteoarthritis

(2010) Fei Zhu et al.   PLoS One

PKA, Rap1, ERK1/2, and p90RSK mediate PGE2 and EP4 signaling in neonatal ventricular myocytes

(2009) Quan He et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Angiogenic growth factors inhibit chondrocyte ageing in osteoarthritis: potential involvement of catabolic stress-induced overexpression of caveolin-1 in cellular ageing

(2009) Kazuo YUDOH et al.   International Journal of Rheumatic Diseases

The Heme Oxygenase-1/Carbon Monoxide Pathway Suppresses TLR4 Signaling by Regulating the Interaction of TLR4 with Caveolin-1

(2009) X. M. Wang et al.   JOURNAL OF IMMUNOLOGY

Elucidation of the signaling network of COX-2 induction in sheared chondrocytes: COX-2 is induced via a Rac/MEKK1/MKK7/JNK2/c-Jun-C/EBPβ-dependent pathway

(2008) Zachary R. Healy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Inhibition of interleukin-1β-induced matrix metalloproteinases 1 and 13 production in human osteoarthritic chondrocytes by prostaglandin D2

(2008) Nadia Zayed et al.   ARTHRITIS AND RHEUMATISM

Regulation of TLR4-induced IL-6 response in bladder cancer cells by opposing actions of MAPK and PI3K signaling

(2008) Yigang Qian et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Increased expression of lipocalin-type prostaglandin D2 synthase in osteoarthritic cartilage

(2008) Nadia Zayed et al.   ARTHRITIS RESEARCH & THERAPY