Applications of the human p53 knock-in (Hupki) mouse model for human carcinogen testing

Wild-type and Hupki (Human p53 Knock-in) Murine Embryonic Fibroblasts

(2010) Catherine Whibley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutational spectra of human cancer

(2009) Gerd P. Pfeifer et al.   HUMAN GENETICS

Cancer genome sequencing: a review

(2009) E. R. Mardis et al.   HUMAN MOLECULAR GENETICS

A small-cell lung cancer genome with complex signatures of tobacco exposure

(2009) Erin D. Pleasance et al.   NATURE

A comprehensive catalogue of somatic mutations from a human cancer genome

(2009) Erin D. Pleasance et al.   NATURE

Next-generation sequencing: applications beyond genomes

(2008) Samuel Marguerat et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Applications of next-generation sequencing technologies in functional genomics

(2008) Olena Morozova et al.   GENOMICS

Sunlight ultraviolet irradiation andBRAFV600 mutagenesis in human melanoma

(2008) Ahmad Besaratinia et al.   HUMAN MUTATION

TP53mutation signature supports involvement of aristolochic acid in the aetiology of endemic nephropathy-associated tumours

(2008) Tatiana Nedelko et al.   INTERNATIONAL JOURNAL OF CANCER

Second-hand smoke and human lung cancer

(2008) Ahmad Besaratinia et al.   LANCET ONCOLOGY

The carcinogenic air pollutant 3-nitrobenzanthrone induces GC to TA transversion mutations in human p53 sequences

(2008) J. vom Brocke et al.   MUTAGENESIS

Mutagenic specificity of N-acetoxy-3-aminobenzanthrone, a major metabolically activated form of 3-nitrobenzanthrone, in shuttle vector plasmids propagated in human cells

(2008) Hiroshi Nishida et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Somatic mutations affect key pathways in lung adenocarcinoma

(2008) Li Ding et al.   NATURE

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE