Article
Multidisciplinary Sciences
Zhu Huang, Wei Zhao, Ying-zheng Mao, Shan Hu, Chi-Xin Du
Summary: This retrospective study collected axial length and corneal aberration data on 78 eyes before and after orthokeratology treatment to identify the factors influencing axial length in children with myopia. The study found that the age when wearing orthokeratology lenses, lens type, and change in the C12 of the total corneal surface were the most important factors influencing axial length.
SCIENTIFIC REPORTS
(2023)
Article
Medicine, General & Internal
Yukari Tsuneyoshi, Sachiko Masui, Hiroyuki Arai, Ikuko Toda, Miyuki Kubota, Shunsuke Kubota, Kazuo Tsubota, Masahiko Ayaki, Kazuno Negishi
Summary: The study found that most patients became aware of presbyopia in their late forties, though some experienced difficulty with near vision tasks before that. Even with excellent NVA at 40 cm and a correction of 0.0 logMAR, 83% of patients still struggled with near vision tasks. Further research is needed to establish appropriate diagnostic criteria and improve management for patients with presbyopia.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Multidisciplinary Sciences
Zengying Wang, Zuocheng Wang, Yifei Meng, Pengfei Wang, Shaniya Yibulayin, Bohua Jiang, Xufei Bian, Tianya Gao, Zhipeng Yan
Summary: The aim of this study was to investigate the changes in posterior corneal surface after 12 months of orthokeratology (ortho-k) treatment. Medical records of 37 Chinese children who wore ortho-k lenses over 12 months were reviewed. The results showed that the anterior corneal surface was significantly changed by ortho-k lens, while the posterior corneal surface did not show any changes during the 12-month follow up. Additionally, the anterior chamber depth, lens thickness, and ocular axis length were significantly changed during this period.
Article
Neurosciences
Guihua Liu, Yiyuan Wu, Hua Bi, Biying Wang, Tianpu Gu, Bei Du, Jianliang Tong, Bin Zhang, Ruihua Wei
Summary: The study aimed to investigate the time course of subjective visual function changes during the first month of orthokeratology treatment in myopic children and explore the associations with objective optical quality changes and axial length growth after 1 year of treatment. Results showed that most children peaked in subjective visual function on day 1 or 1 week after lens fitting, with no significant differences in axial growth among children with different peak days.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Ophthalmology
Yin Guo, Lizhou Liu, Li Peng, Jia Fu, Wei Guo, Ping Tang
Summary: The purpose of this study was to evaluate tear film surface quality after orthokeratology using the Medmont E300 corneal topographer. The results showed that tear film disruption was significantly increased in children wearing orthokeratology lenses, but returned to baseline levels after 1 month of lens cessation.
CONTACT LENS & ANTERIOR EYE
(2023)
Article
Ophthalmology
Yunyun Chen, Chenglu Ding, Xue Li, Yingying Huang, Fengchao Zhou, Bjorn Drobe, Hao Chen, Jinhua Bao
Summary: The aim of this study was to evaluate the short-term effects of peripheral gradient high-addition multifocal soft contact lenses and orthokeratology on visual performance in myopic children. The results showed that both MFSCLs and Ortho-K lenses significantly increased aberrations compared to single-vision spectacles. MFSCLs performed slightly worse than Ortho-K lenses in terms of low-contrast visual acuity.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2023)
Article
Nanoscience & Nanotechnology
Kun-Ling Li, Jing Wang, Heng Zhao, Jie Li, Li-Ya Zheng, Jin-Tao Si, Li Li, Peng Chen, Guang Chen
Summary: This study investigated the impact of using monocular orthokeratology lenses on axial length and the progress of anisometropia in children. Thirty children aged 8-12 years with myopic anisometropia were divided into an orthokeratology-using group and a non-using group. The study found that using monocular orthokeratology lenses effectively controlled the increase in axial length and the worsening of myopia, and also corrected anisometropia.
Article
Health Care Sciences & Services
Xiaohang Chen, Qiushi Li, Longqian Liu
Summary: This study aimed to identify risk factors for changes in subfoveal choroidal thickness after orthokeratology and provide personalized information for myopia control. The results showed that subfoveal choroidal thickness significantly changed after 12 months of lens wearing. Axial length and average near-work time were identified as important factors influencing the changes in subfoveal choroidal thickness.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Ophthalmology
Mark A. Bullimore, Dmitry S. Mirsayafov, Aslan R. Khurai, Leonid B. Kononov, Suzanna P. Asatrian, Andrei N. Shmakov, Kathryn Richdale, Valery V. Gorev
Summary: The study aimed to estimate the incidence of microbial keratitis in children wearing overnight orthokeratology lenses in Moscow, Russia. The results showed that the incidence of microbial keratitis in children wearing overnight orthokeratology lenses was lower than a previous study in the United States and similar to rates associated with the use of daily wear soft contact lenses.
EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE
(2021)
Article
Medicine, Research & Experimental
Bo-Yie Chen, Jyh-Cheng Liou, Jia-Lain Wu, Chao-Hsiang Chen, Shih-Liang Yang
Summary: Astragaloside IV showed protective effects against light-induced functional vision deterioration, especially on cone cells, improving visual acuity and contrast sensitivity function in mice.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Clinical Neurology
Xiaohang Chen, Yan Xiong, Xinzhou Qi, Longqian Liu
Summary: The objective of this study was to observe the changes in peripheral refraction in myopic adolescents after overnight orthokeratology and its influencing factors. The results showed that after wearing orthokeratology lenses, the relative peripheral refraction in myopic patients changed from relative hyperopia to relative myopia, and the nasal-temporal asymmetry also changed significantly. This change was correlated with the baseline refractive state.
FRONTIERS IN NEUROLOGY
(2023)
Article
Multidisciplinary Sciences
Yoo-Ri Chung, Young Ho Kim, Jaeryung Oh, Seong-Woo Kim, Christopher Seungkyu Lee, Cheolmin Yun, Boram Lee, So Min Ahn, Eun Young Choi, Sungmin Jang, Kihwang Lee
Summary: In this study, structural findings on SD-OCT related to the presence of RAV in MacTel type 2 eyes with severity 3 in Korea were investigated. Eyes with RAV showed a higher frequency of IR disorganization, OR cavity, and EZ disruption on SD-OCT compared to eyes without RAV. These findings suggest that the presence of RAV is closely associated with advanced stages of MacTel type 2.
SCIENTIFIC REPORTS
(2021)
Article
Multidisciplinary Sciences
Mohammad Zarei, Hossein Pesarakli, Mehdi Yaseri, Hamed Etesali, Nazanin Ebrahimiadib
Summary: This study investigated the correlation of OCT parameters with fluorescein angiography in evaluating inflammatory activity in Behcet's retinal vasculitis. Results showed that parameters such as CSMT, PRT2.2, PRT3.45, and PNFLT had significant correlation with FA scores, with PRT3.45 and PNFLT showing the strongest correlation with angiographic inflammatory activity. These parameters may serve as non-invasive alternatives to FA for monitoring Behcet's retinal vasculitis.
SCIENTIFIC REPORTS
(2021)
Article
Ophthalmology
Ahmed A. Zein El-Dein, Ahmed Elmassry, Hazem M. El-Hennawi, Ehab F. Mossallam
Summary: The study demonstrates that implantation of trifocal diffractive intraocular lens can effectively improve patients' visual outcomes and quality, with most patients being highly satisfied and achieving independence from wearing glasses postoperatively.
Article
Multidisciplinary Sciences
C. Vijay Reena Durai, Amithavikram R. R. Hathibelagal, Marisa Rodriguez-Carmona, John L. L. Barbur, Shrikant R. R. Bharadwaj
Summary: The present study investigates the impact of monocular sensitivity on binocular detection of luminance-modulated flickering stimuli. The results show that binocular summation ratios (BSRs) successfully summate inputs from the two eyes to enhance flicker detection, independent of their absolute monocular detection thresholds.
Article
Ophthalmology
Jose Vicente Garcia-Marques, Rute Macedo-de-Araujo, Daniela Lopes-Ferreira, Alejandro Cervino, Santiago Garcia-Lazaro, Jose Manuel Gonzalez-Meijome
Summary: The study found that the dual-focus contact lens design compared to the monofocal lens resulted in a slight reduction in short-term pre-lens tear film stability, potentially affecting visual performance and comfort during dual-focus contact lens wear.
CLINICAL AND EXPERIMENTAL OPTOMETRY
(2022)
Article
Ophthalmology
Jose Vicente Garcia-Marques, Rute Juliana Macedo-De-Araujo, Alejandro Cervino, Santiago Garcia-Lazaro, Jose Manuel Gonzalez-Meijome
Summary: The study aimed to validate an algorithm for assessing meibomian gland visibility and evaluate changes in meibomian glands in scleral lens wearers over one year. Infrared meibography images were obtained and classified into groups based on gland visibility. The proposed method showed objective and repeatable assessment of meibomian gland visibility. Scleral lens wear did not negatively affect gland drop-out and visibility, and may even improve dry eye symptoms after one year.
CONTACT LENS & ANTERIOR EYE
(2023)
Article
Ophthalmology
Cristian Talens-Estarelles, Jose Vicente Garcia-Marques, Alejandro Cervino, Santiago Garcia-Lazaro
Summary: The study aimed to identify the impact of computer use on dry eye and its association with ocular parameters. The results showed that individuals with more severe dry eye symptoms were more likely to experience an increase in symptoms during computer use, while those with poorer tear stability were more likely to experience a reduction in tear stability.
CLINICAL AND EXPERIMENTAL OPTOMETRY
(2023)
Article
Ophthalmology
Paulo Fernandes, Cesarina Ferreira, Joana Domingues, Ana Amorim-de-Sousa, Miguel Faria-Ribeiro, Antonio Queiros, Jose M. Gonzalez-Meijome
Summary: Multifocal contact lenses have a significant impact on retinal activity, with the greatest effect observed in the center-near design. The findings suggest that there may be a delay in retinal response during adaptation to multifocality.
DOCUMENTA OPHTHALMOLOGICA
(2022)
Article
Biology
Jose Vicente Garcia-Marques, Cristian Talens-Estarelles, Santiago Garcia-Lazaro, Alejandro Cervino
Summary: This study aims to evaluate the effects of soft contact lens wear and its duration on tear film and meibomian gland. The results showed that contact lens wearers had higher meibomian gland dropout and lower gland visibility. Prolonged contact lens wear was associated with increased dry eye symptoms and entropy of the meibomian glands.
Article
Medicine, General & Internal
Antonio Queiros, Ana Amorim-de-Sousa, Paulo Fernandes, Maria Sameiro Ribeiro-Queiros, Cesar Villa-Collar, Jose M. Gonzalez-Meijome
Summary: This study aims to evaluate and develop mathematical models for estimating axial length (AL) in a cross-sectional and longitudinal sample. The existing mathematical equation proposed by Morgan was found to have statistically significant differences in AL estimation based on gender, ametropia, type of astigmatism, and age. A new mathematical model was proposed and tested, showing no statistically significant differences in axial length estimation between the models in a longitudinal sample. Despite errors in predicted axial length values, the mathematical equations are valid for estimating differences in axial increment for ages between 9 and 24 years.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Ana Amorim-de-Sousa, Jaume Paune, Sara Silva-Leite, Paulo Fernandes, Jose Manuel Gozalez-Meijome, Antonio Queiros
Summary: The effect of a contact lens (CL) intended for myopia control on choroidal thickness (ChT) and retinal electrical response was investigated. It was found that the radial power gradient CL (PG) increased ChT and attenuated the amplitude of retinal response. These effects may be due to the combined impact of induced peripheral defocus and high-order aberrations on the central retinal image.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Sara Silva-Leite, Ana Amorim-de-Sousa, Antonio Queiros, Jose Manuel Gonzalez-Meijome, Paulo Fernandes
Summary: This study aimed to evaluate the peripheral defocus induced with a perifocal ophthalmic lens for myopia progression control and its impact on visual function. The study found that the perifocal lenses induced myopic defocus on the nasal retina but not on the temporal retina. Additionally, there were no significant differences in visual contrast sensitivity and light disturbance between the monofocal and perifocal lenses.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Optics
Maria Mecho-Garcia, Inaki Blanco-Martinez, Paulo Fernandes, Rute J. Macedo-de-Araujo, Miguel Faria-Ribeiro, Jose Manuel Gonzalez-Meijome
Summary: This study aimed to investigate the effect of pupil dilation with Phenylephrine Hydrochloride (PHCl) on the accommodative response and Zernike coefficient magnitude. Results showed statistically significant differences in the Zernike coefficients C-3(-1), C-3(1), C-4(0), and C-6(0) between natural conditions and after pupil dilation with PHCl.
Article
Optics
Ana Amorim-de-Sousa, Paulo Fernandes, Noberto Lopez-Gil, Antonio Queiros, Jose M. Gonzalez-Meijome
Summary: The purpose of this study was to investigate the retinal electrical activity in response to grids of different spatial orientations. The results showed that the retinal response was higher with grids of parallel orientation to the retinal meridians and lower with perpendicularly oriented grids. These findings are important for understanding eye growth regulation and myopia control treatments.
Article
Pediatrics
Antonio Queiros, Pauline Beaujeux, Louisette Bloise, Aurelia Chaume, Jean Philippe Colliot, Dominique Plaisant Proust, Perrine Rossi, Bertrand Tritsch, Dominique Bastien Crinon, Jaume Paune
Summary: The purpose of this study was to evaluate the effect of orthokeratology treatment with DRL lenses on myopia progression compared to single vision glasses users. A 2-year retrospective multicenter study was conducted in France to analyze the clinical efficacy of orthokeratology treatment with DRL lenses for myopia correction in children and adolescents. The results showed that after 1 and 2 years of treatment, orthokeratology with DRL lenses had a significant control effect on myopia compared to spectacle wearers.
Editorial Material
Biology
Jose-Maria Sanchez-Gonzalez, Carlos Rocha-de-Lossada, Alejandro Cervino