期刊
EXPERT REVIEWS IN MOLECULAR MEDICINE
卷 15, 期 -, 页码 -出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/erm.2013.14
关键词
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资金
- Great Ormond Street Children's Charity
- National Institute for Health research (NIHR), UK
- Nuffield Oliver Bird Programme
In recent years, there have been many new developments in the field of regulatory T cells (Treg), challenging the consensus on their behaviour, classification and role(s) in disease. The role Treg might play in autoimmune disease appears to be more complex than previously thought. Here, we discuss the current knowledge of regulatory T cells through animal and human research and illustrate the recent developments in childhood autoimmune arthritis (juvenile idiopathic arthritis (JIA)). Furthermore, this review summarises our understanding of the fields and assesses current and future implications for Treg in the treatment of JIA.
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