T-cell-receptor-like antibodies – generation, function and applications

An anti-PR1/HLA-A2 T-cell receptor-like antibody mediates complement-dependent cytotoxicity against acute myeloid leukemia progenitor cells

(2011) A. Sergeeva et al.   BLOOD

A systematic review of treatment guidelines for metastatic colorectal cancer

(2011) M. S. Edwards et al.   Colorectal Disease

Therapeutic potential of anticancer immunotoxins

(2011) Swati Choudhary et al.   DRUG DISCOVERY TODAY

TCR Mimic Monoclonal Antibodies Induce Apoptosis of Tumor Cells via Immune Effector-Independent Mechanisms

(2011) B. Verma et al.   JOURNAL OF IMMUNOLOGY

MHC class I-presented lung cancer-associated tumor antigens identified by immunoproteomics analysis are targets for cancer-specific T cell response

(2011) Vivekananda Shetty et al.   Journal of Proteomics

A Neutralizing Antibody Selected from Plasma Cells That Binds to Group 1 and Group 2 Influenza A Hemagglutinins

(2011) D. Corti et al.   SCIENCE

Therapeutic antibodies: Discovery and development using the ProteOn XPR36 biosensor interaction array system

(2010) Vered Bronner et al.   ANALYTICAL BIOCHEMISTRY

Dendritic Cell-Based Immunotherapy for Prostate Cancer

(2010) Hanka Jähnisch et al.   Clinical & Developmental Immunology

Successful Treatment of Melanoma Brain Metastases with Adoptive Cell Therapy

(2010) J. J. Hong et al.   CLINICAL CANCER RESEARCH

Direct visualization of the dynamics of antigen presentation in human cells infected with cytomegalovirus revealed by antibodies mimicking TCR specificity

(2010) Oryan Makler et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

TCR Mimic Monoclonal Antibody Targets a Specific Peptide/HLA Class I Complex and Significantly Impedes Tumor Growth In Vivo Using Breast Cancer Models

(2010) Bhavna Verma et al.   JOURNAL OF IMMUNOLOGY

Antibodies and Lentiviruses That Specifically Recognize a T Cell Epitope Derived from HIV-1 Nef Protein and Presented by HLA-C

(2010) A. Herschhorn et al.   JOURNAL OF IMMUNOLOGY

Evidence for a TCR Affinity Threshold Delimiting Maximal CD8 T Cell Function

(2010) D. A. Schmid et al.   JOURNAL OF IMMUNOLOGY

Targeting Hepatitis B Virus-Infected Cells with a T-Cell Receptor-Like Antibody

(2010) K. S. R. Sastry et al.   JOURNAL OF VIROLOGY

Short Communication: Generation of Recombinant Monoclonal Antibodies against an Immunodominant HLA-A*2402-Restricted HIV Type 1 CTL Epitope

(2009) Jun-Ichi Nunoya et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Expression Hierarchy of T Cell Epitopes from Melanoma Differentiation Antigens: Unexpected High Level Presentation of Tyrosinase-HLA-A2 Complexes Revealed by Peptide-Specific, MHC-Restricted, TCR-Like Antibodies

(2009) Yael Michaeli et al.   JOURNAL OF IMMUNOLOGY

Rational development of high-affinity T-cell receptor-like antibodies

(2009) G. Stewart-Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antitumor Activity of Immunotoxins with T-Cell Receptor-like Specificity against Human Melanoma Xenografts

(2008) E. Klechevsky et al.   CANCER RESEARCH

Tumor Escape Mechanism Governed by Myeloid-Derived Suppressor Cells

(2008) S. Nagaraj et al.   CANCER RESEARCH

Targeting TARP, a novel breast and prostate tumor-associated antigen, with T cell receptor-like human recombinant antibodies

(2008) Malka Epel et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

(2008) Martin A Pule et al.   NATURE MEDICINE

Assessing vaccine potency using TCRmimic antibodies

(2008) Francisca A. Neethling et al.   VACCINE