Oncolytic virotherapy for pancreatic cancer

Urokinase-Type Plasminogen Activator Receptor Transcriptionally Controlled Adenoviruses Eradicate Pancreatic Tumors and Liver Metastasis in Mouse Models

(2015) Meritxell Huch et al.   NEOPLASIA

Immune cells participate in the oncosuppressive activity of parvovirus H-1PV and are activated as a result of their abortive infection with this agent

(2011) Svitlana P. Grekova et al.   CANCER BIOLOGY & THERAPY

Cancer Statistics, 2010

(2010) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

A phase I dose-escalation clinical trial of intraoperative direct intratumoral injection of HF10 oncolytic virus in non-resectable patients with advanced pancreatic cancer

(2010) A Nakao et al.   CANCER GENE THERAPY

Combination with low-dose gemcitabine and hTERT-promoter-dependent conditionally replicative adenovirus enhances cytotoxicity through their crosstalk mechanisms in pancreatic cancer

(2010) Manabu Onimaru et al.   CANCER LETTERS

Improved Potency and Selectivity of an Oncolytic E1ACR2 and E1B19K Deleted Adenoviral Mutant in Prostate and Pancreatic Cancers

(2010) D. Oberg et al.   CLINICAL CANCER RESEARCH

Therapeutic Potential of Oncolytic Measles Virus: Promises and Challenges

(2010) E Galanis   CLINICAL PHARMACOLOGY & THERAPEUTICS

Clinical trials with oncolytic reovirus: Moving beyond phase I into combinations with standard therapeutics

(2010) K.J. Harrington et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Oncolytic parvoviruses as cancer therapeutics

(2010) Jean Rommelaere et al.   CYTOKINE & GROWTH FACTOR REVIEWS

New perspectives in cancer virotherapy: bringing the immune system into play

(2010) Nicolas Boisgerault et al.   Immunotherapy

Enhancement of NK cell antitumor responses using an oncolytic parvovirus

(2010) Rauf Bhat et al.   INTERNATIONAL JOURNAL OF CANCER

FOLFIRINOX: a new standard treatment for advanced pancreatic cancer?

(2010) Richard Kim   LANCET ONCOLOGY

Molecular mechanism of pancreatic cancer—understanding proliferation, invasion, and metastasis

(2010) André L. Mihaljevic et al.   LANGENBECKS ARCHIVES OF SURGERY

Potent Oncolytic Activity of Raccoonpox Virus in the Absence of Natural Pathogenicity

(2010) Laura Evgin et al.   MOLECULAR THERAPY

Desmoglein 2 is a receptor for adenovirus serotypes 3, 7, 11 and 14

(2010) Hongjie Wang et al.   NATURE MEDICINE

The viral tropism of two distinct oncolytic viruses, reovirus and myxoma virus, is modulated by cellular tumor suppressor gene status

(2010) M Kim et al.   ONCOGENE

New pancreatic carcinoma model for studying oncolytic adenoviruses in the permissive Syrian hamster

(2009) J F Spencer et al.   CANCER GENE THERAPY

The immunologic aspects of poxvirus oncolytic therapy

(2009) Andrea Worschech et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Acquisition of Epithelial-Mesenchymal Transition Phenotype of Gemcitabine-Resistant Pancreatic Cancer Cells Is Linked with Activation of the Notch Signaling Pathway

(2009) Z. Wang et al.   CANCER RESEARCH

Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer

(2009) T. Arumugam et al.   CANCER RESEARCH

Combination of conditionally replicative adenovirus and standard chemotherapies shows synergistic antitumor effect in pancreatic cancer

(2009) Amy R. Nelson et al.   CANCER SCIENCE

hTERT-promoter-dependent oncolytic adenovirus enhances the transduction and therapeutic efficacy of replication-defective adenovirus vectors in pancreatic cancer cells

(2009) Manabu Onimaru et al.   CANCER SCIENCE

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

Oncolytic Adenoviral Mutants with E1B19K Gene Deletions Enhance Gemcitabine-induced Apoptosis in Pancreatic Carcinoma Cells and Anti-Tumor Efficacy In vivo

(2009) S. Leitner et al.   CLINICAL CANCER RESEARCH

Reexpression of Human Somatostatin Receptor Gene 2 Gene Mediated by Oncolytic Adenovirus Increases Antitumor Activity of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand against Pancreatic Cancer

(2009) Z. Zhang et al.   CLINICAL CANCER RESEARCH

Improvement of Gemcitabine-Based Therapy of Pancreatic Carcinoma by Means of Oncolytic Parvovirus H-1PV

(2009) A. L. Angelova et al.   CLINICAL CANCER RESEARCH

Novel agents for the treatment of adenocarcinoma of the pancreas

(2009) R Pamela Mackenzie et al.   Expert Review of Anticancer Therapy

Lister strain vaccinia virus, a potential therapeutic vector targeting hypoxic tumours

(2009) C T Hiley et al.   GENE THERAPY

Lister strain of vaccinia virus armed with endostatin–angiostatin fusion gene as a novel therapeutic agent for human pancreatic cancer

(2009) J R Tysome et al.   GENE THERAPY

Oncolytic virus therapy for pancreatic cancer using the adenovirus library displaying random peptides on the fiber knob

(2009) T Nishimoto et al.   GENE THERAPY

Randomized Phase II Study of Gemcitabine Administered at a Fixed Dose Rate or in Combination With Cisplatin, Docetaxel, or Irinotecan in Patients With Metastatic Pancreatic Cancer: CALGB 89904

(2009) Matthew H. Kulke et al.   JOURNAL OF CLINICAL ONCOLOGY

Viral Oncolysis That Targets Raf-1 Signaling Control of Nuclear Transport

(2009) L. Riolobos et al.   JOURNAL OF VIROLOGY

Regression of human pancreatic tumor xenografts in mice after a single systemic injection of recombinant vaccinia virus GLV-1h68

(2009) Y. A. Yu et al.   MOLECULAR CANCER THERAPEUTICS

Treatment of Pancreatic Cancer With an Oncolytic Adenovirus Expressing Interleukin-12 in Syrian Hamsters

(2009) Sergia Bortolanza et al.   MOLECULAR THERAPY

Intelligent Design: Combination Therapy With Oncolytic Viruses

(2009) Kathryn Ottolino-Perry et al.   MOLECULAR THERAPY

Reovirus inhibits the peritoneal dissemination of pancreatic cancer cells in an immunocompetent animal model

(2009) Hirano   ONCOLOGY REPORTS

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

(2009) K. P. Olive et al.   SCIENCE

Quantitative Molecular Imaging of Viral Therapy for Pancreatic Cancer Using an Engineered Measles Virus Expressing the Sodium-Iodide Symporter Reporter Gene

(2008) Stephanie K. Carlson et al.   AMERICAN JOURNAL OF ROENTGENOLOGY

Optimization of conditionally replicative adenovirus for pancreatic cancer and its evaluation in an orthotopic murine xenograft model

(2008) Pedro J. Ramírez et al.   AMERICAN JOURNAL OF SURGERY

Myxoma Virus Is Oncolytic for Human Pancreatic Adenocarcinoma Cells

(2008) Yanghee Woo et al.   ANNALS OF SURGICAL ONCOLOGY

A Phase I Study of Intravenous Oncolytic Reovirus Type 3 Dearing in Patients with Advanced Cancer

(2008) L. Vidal et al.   CLINICAL CANCER RESEARCH

Oncolytic Efficacy of Recombinant Vesicular Stomatitis Virus and Myxoma Virus in Experimental Models of Rhabdoid Tumors

(2008) Y. Wu et al.   CLINICAL CANCER RESEARCH

Generation of optimized and urokinase-targeted oncolytic Sendai virus vectors applicable for various human malignancies

(2008) H Kinoh et al.   GENE THERAPY

Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trial

(2008) C L White et al.   GENE THERAPY

Taming the Trojan horse: optimizing dynamic carrier cell/oncolytic virus systems for cancer biotherapy

(2008) A T Power et al.   GENE THERAPY

A Phase I Trial of Intratumoral Administration of Reovirus in Patients With Histologically Confirmed Recurrent Malignant Gliomas

(2008) Peter Forsyth et al.   MOLECULAR THERAPY

Reprogrammed viruses as cancer therapeutics: targeted, armed and shielded

(2008) Roberto Cattaneo et al.   NATURE REVIEWS MICROBIOLOGY

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE

Myxoma Virus Oncolysis of Primary and Metastatic B16F10 Mouse Tumors In Vivo

(2007) Marianne M Stanford et al.   MOLECULAR THERAPY