Insect cells as a production platform of complex virus-like particles

Co-expression vs. co-infection using baculovirus expression vectors in insect cell culture: Benefits and drawbacks

(2012) Stanislav Sokolenko et al.   BIOTECHNOLOGY ADVANCES

Flipase-mediated cassette exchange inSf9insect cells for stable gene expression

(2012) Fabiana Fernandes et al.   BIOTECHNOLOGY AND BIOENGINEERING

Vaccine process technology

(2012) Jessica O. Josefsberg et al.   BIOTECHNOLOGY AND BIOENGINEERING

HIV-1 Virus-Like Particles Produced by Stably Transfected Drosophila S2 Cells: a Desirable Vaccine Component

(2012) L. Yang et al.   JOURNAL OF VIROLOGY

SweetBac: A New Approach for the Production of Mammalianised Glycoproteins in Insect Cells

(2012) Dieter Palmberger et al.   PLoS One

On the Effect of Thermodynamic Equilibrium on the Assembly Efficiency of Complex Multi-Layered Virus-Like Particles (VLP): the Case of Rotavirus VLP

(2012) António Roldão et al.   PLoS Computational Biology

Rational design and optimization of downstream processes of virus particles for biopharmaceutical applications: Current advances

(2011) Tiago Vicente et al.   BIOTECHNOLOGY ADVANCES

Production of influenza pseudotyped lentiviral particles and their use in influenza research and diagnosis: an update

(2011) Jean-Michel Garcia et al.   Expert Review of Anti-Infective Therapy

Virus‑like particles as a vaccine delivery system: Myths and facts

(2011) Polly Roy et al.   Human vaccines & immunotherapeutics

Progress in the development of preventive and therapeutic vaccines for hepatitis C virus

(2011) Joseph Torresi et al.   JOURNAL OF HEPATOLOGY

Viruslike Particle Vaccine Induces Protection Against Respiratory Syncytial Virus Infection in Mice

(2011) Fu-Shi Quan et al.   JOURNAL OF INFECTIOUS DISEASES

A fast track influenza virus vaccine produced in insect cells

(2011) Manon M.J. Cox et al.   JOURNAL OF INVERTEBRATE PATHOLOGY

Recombinase-Mediated Cassette Exchange (RMCE): Traditional Concepts and Current Challenges

(2011) Soeren Turan et al.   JOURNAL OF MOLECULAR BIOLOGY

MultiBac: expanding the research toolbox for multiprotein complexes

(2011) Christoph Bieniossek et al.   TRENDS IN BIOCHEMICAL SCIENCES

Safety and immunogenicity of a virus-like particle pandemic influenza A (H1N1) 2009 vaccine in a blinded, randomized, placebo-controlled trial of adults in Mexico

(2011) Constantino López-Macías et al.   VACCINE

Engineering of baculovirus vectors for the manufacture of virion-free biopharmaceuticals

(2010) Martin Marek et al.   BIOTECHNOLOGY AND BIOENGINEERING

High-level expression and improved folding of proteins by using the vp39 late promoter enhanced with homologous DNA regions

(2010) Seiji Ishiyama et al.   BIOTECHNOLOGY LETTERS

Synthesis of double-layered rotavirus-like particles using internal ribosome entry site vector system in stably-transformed Drosophila melanogaster

(2010) Jong Min Lee et al.   BIOTECHNOLOGY LETTERS

Molecular and structural characterization of the L1 virus-like particles that are used as vaccine antigens inCervarix™, the AS04-adjuvanted HPV-16 and -18 cervical cancer vaccine

(2010) Michel Deschuyteneer et al.   Human vaccines & immunotherapeutics

New baculovirus expression tools for recombinant protein complex production

(2010) Simon Trowitzsch et al.   JOURNAL OF STRUCTURAL BIOLOGY

Influenza virus-like particles as an antigen-carrier platform for the ESAT-6 epitope of Mycobacterium tuberculosis

(2010) Florian Krammer et al.   JOURNAL OF VIROLOGICAL METHODS

Trichoplusia ni cells (High FiveTM) are highly efficient for the production of influenza A virus-like particles: a comparison of two insect cell lines as production platforms for influenza vaccines

(2010) Florian Krammer et al.   MOLECULAR BIOTECHNOLOGY

Constitutive expression of HIV-VLPs in stably transfected insect cell line for efficient delivery system

(2010) M. Tagliamonte et al.   VACCINE

Immunization by influenza virus-like particles protects aged mice against lethal influenza virus challenge

(2009) Zhiyuan Wen et al.   ANTIVIRAL RESEARCH

Cell density effect in the baculovirus-insect cells system: A quantitative analysis of energetic metabolism

(2009) Vicente Bernal et al.   BIOTECHNOLOGY AND BIOENGINEERING

Genetic modification of a baculovirus vector for increased expression in insect cells

(2009) Richard B. Hitchman et al.   CELL BIOLOGY AND TOXICOLOGY

Virus-like particle vaccines and adjuvants: the HPV paradigm

(2009) Franco Maria Buonaguro et al.   Expert Review of Vaccines

Improving baculovirus production at high cell density through manipulation of energy metabolism

(2009) Nuno Carinhas et al.   METABOLIC ENGINEERING

Induction of Long-Term Protective Immune Responses by Influenza H5N1 Virus-Like Particles

(2009) Sang-Moo Kang et al.   PLoS One

Validation of a novel approach for the rapid production of immunogenic virus-like particles for bluetongue virus

(2009) M. Stewart et al.   VACCINE

Enhanced papillomavirus-like particle production in insect cells

(2009) Tilo Senger et al.   VIROLOGY

Protection against filovirus infection: virus-like particle vaccines

(2008) Chinglai Yang et al.   Expert Review of Vaccines

Low multiplicity of infection in vivo results in purifying selection against baculovirus deletion mutants

(2008) M. P. Zwart et al.   JOURNAL OF GENERAL VIROLOGY

Rotavirus epidemiology: The Asian Rotavirus Surveillance Network

(2008) E.A.S. Nelson et al.   VACCINE

Influenza-pseudotyped Gag virus-like particle vaccines provide broad protection against highly pathogenic avian influenza challenge

(2008) Joel R. Haynes et al.   VACCINE

Protection against lethal challenge by Ebola virus-like particles produced in insect cells

(2008) Yuliang Sun et al.   VIROLOGY

Stochastic simulation of protein expression in the baculovirus/insect cells system

(2007) António Roldão et al.   COMPUTERS & CHEMICAL ENGINEERING