Immunologic correlates of protection and potential role for adjuvants to improve influenza vaccines in older adults

The aged microenvironment contributes to the age-related functional defects of CD4 T cells in mice

(2012) Julie S. Lefebvre et al.   AGING CELL

The Importance of Adjuvant Formulation in the Development of a Tuberculosis Vaccine

(2012) S. L. Baldwin et al.   JOURNAL OF IMMUNOLOGY

Adjuvant solution for pandemic influenza vaccine production

(2012) C. H. Clegg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trivalent inactivated influenza vaccines induce broad immunological reactivity to both internal virion components and influenza surface proteins

(2012) Katherine A. Richards et al.   VACCINE

Immunogenicity, Boostability, and Sustainability of the Immune Response after Vaccination against Influenza A Virus (H1N1) 2009 in a Healthy Population

(2011) Elisabeth Huijskens et al.   Clinical and Vaccine Immunology

GLA-SE, a Synthetic Toll-like Receptor 4 Agonist, Enhances T-Cell Responses to Influenza Vaccine in Older Adults

(2011) Hayedeh Behzad et al.   JOURNAL OF INFECTIOUS DISEASES

Development and Characterization of Synthetic Glucopyranosyl Lipid Adjuvant System as a Vaccine Adjuvant

(2011) Rhea N. Coler et al.   PLoS One

Age-related changes in memory and effector T cells responding to influenza A/H3N2 and pandemic A/H1N1 strains in humans

(2011) Xin Zhou et al.   VACCINE

Toll-like receptor expression and function in human dendritic cell subsets: implications for dendritic cell-based anti-cancer immunotherapy

(2010) Gerty Schreibelt et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Influenza-Induced Production of Interferon-Alpha is Defective in Geriatric Individuals

(2010) David H. Canaday et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Immuno-epidemiologic Correlates of Pandemic H1N1 Surveillance Observations: Higher Antibody and Lower Cell-Mediated Immune Responses with Advanced Age

(2010) D. M. Skowronski et al.   JOURNAL OF INFECTIOUS DISEASES

A Synthetic Adjuvant to Enhance and Expand Immune Responses to Influenza Vaccines

(2010) Rhea N. Coler et al.   PLoS One

Vaccines with MF59 Adjuvant Expand the Antibody Repertoire to Target Protective Sites of Pandemic Avian H5N1 Influenza Virus

(2010) S. Khurana et al.   Science Translational Medicine

A Defined Tuberculosis Vaccine Candidate Boosts BCG and Protects Against Multidrug-Resistant Mycobacterium tuberculosis

(2010) S. Bertholet et al.   Science Translational Medicine

Clinical and immunologic predictors of influenza illness among vaccinated older adults

(2010) Zainab Shahid et al.   VACCINE

Standardization and validation of assays determining cellular immune responses against influenza

(2010) Karlijn Gijzen et al.   VACCINE

Aging Promotes Neutrophil-Induced Mortality by Augmenting IL-17 Production during Viral Infection

(2009) Heather W. Stout-Delgado et al.   Cell Host & Microbe

MF59®-Adjuvanted H5N1 Vaccine Induces Immunologic Memory and Heterotypic Antibody Responses in Non-Elderly and Elderly Adults

(2009) Angelika Banzhoff et al.   PLoS One

Fast rise of broadly cross-reactive antibodies after boosting long-lived human memory B cells primed by an MF59 adjuvanted prepandemic vaccine

(2009) G. Galli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adjuvanted H5N1 vaccine induces early CD4+ T cell response that predicts long-term persistence of protective antibody levels

(2009) G. Galli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Granzyme B: Correlates with protection and enhanced CTL response to influenza vaccination in older adults

(2009) Janet E. McElhaney et al.   VACCINE

Influenza control in the 21st century: Optimizing protection of older adults

(2009) Arnold S. Monto et al.   VACCINE

Intradermal Influenza Vaccine Administered Using a New Microinjection System Produces Superior Immunogenicity in Elderly Adults: A Randomized Controlled Trial

(2008) David Holland et al.   JOURNAL OF INFECTIOUS DISEASES

FDA/NIH/WHO public workshop on immune correlates of protection against influenza A viruses in support of pandemic vaccine development, Bethesda, Maryland, US, December 10–11, 2007

(2008) Maryna Eichelberger et al.   VACCINE