期刊
EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
卷 11, 期 7, 页码 741-755出版社
TAYLOR & FRANCIS AS
DOI: 10.1586/ERM.11.50
关键词
DNA; documentary standards; external quality assessment; genetic testing; infectious disease diagnostics; molecular methods; NAT; nucleic acid testing; proficiency testing; reference material
类别
There is a great need for harmonization in nucleic acid testing for infectious disease and clinical genetics. The proliferation of assay methods, the number of targets for molecular diagnostics and the absence of standard reference materials contribute to variability in test results among laboratories. This article provides a comprehensive overview of reference materials, related documentary standards and proficiency testing programs. The article explores the relationships among these resources and provides necessary information for people practicing in this area that is not taught in formal courses and frequently is obtained on an ad hoc basis. The aim of this article is to provide helpful tools for molecular diagnostic laboratories.
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