期刊
EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
卷 8, 期 3, 页码 315-325出版社
TAYLOR & FRANCIS AS
DOI: 10.1586/14737159.8.3.315
关键词
(1-3)-beta-D-glucan; antibody detection; Candida; D-arabinitol; diagnosis; invasive candidiasis; mannan; microarray; PCR; recombinant antigen
类别
Invasive candidiasis is the most important opportunistic fungal infection, causing high morbidity and mortality. Traditional methods of diagnosis, which include blood culture and biopsy, usually lack both sensitivity and specificity, or become positive late in the course of the infection. Therefore, new nonculture-based methods are being developed. In this review, we will discuss the most recent studies concerning the use of serum biomarkers in the diagnosis of invasive Candida infections.
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