标题
Insights into melanoma: targeting the mTOR pathway for therapeutics
作者
关键词
-
出版物
EXPERT OPINION ON THERAPEUTIC TARGETS
Volume 16, Issue 7, Pages 689-705
出版商
Informa Healthcare
发表日期
2012-05-24
DOI
10.1517/14728222.2012.691472
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Axitinib (AG-013736) in patients with metastatic melanoma: A phase II study
- (2017) J. P. Fruehauf et al. JOURNAL OF CLINICAL ONCOLOGY
- A phase I dose finding and biomarker study of TKI258 (dovitinib lactate) in patients with advanced melanoma
- (2017) K. B. Kim et al. JOURNAL OF CLINICAL ONCOLOGY
- Safety and efficacy results from the first-in-human study of the oral MEK 1/2 inhibitor GSK1120212.
- (2017) J. R. Infante et al. JOURNAL OF CLINICAL ONCOLOGY
- First-line temozolomide combined with bevacizumab in metastatic melanoma: a multicentre phase II trial (SAKK 50/07)
- (2011) R. von Moos et al. ANNALS OF ONCOLOGY
- Ipilimumab: A Novel Treatment for Metastatic Melanoma
- (2011) Morgan E Culver et al. ANNALS OF PHARMACOTHERAPY
- Resistance to Selective BRAF Inhibition Can Be Mediated by Modest Upstream Pathway Activation
- (2011) F. Su et al. CANCER RESEARCH
- Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation
- (2011) Paul B. Chapman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Role and therapeutic potential of PI3K-mTOR signaling in de novo resistance to BRAF inhibition
- (2011) W. Deng et al. Pigment Cell & Melanoma Research
- Reversing Melanoma Cross-Resistance to BRAF and MEK Inhibitors by Co-Targeting the AKT/mTOR Pathway
- (2011) Mohammad Atefi et al. PLoS One
- Analysis of GNAQ mutations, proliferation and MAPK pathway activation in uveal melanomas
- (2010) H. Populo et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Vertical Targeting of the Phosphatidylinositol-3 Kinase Pathway as a Strategy for Treating Melanoma
- (2010) S. A. Aziz et al. CLINICAL CANCER RESEARCH
- Mitogen-Activated Protein/Extracellular Signal-Regulated Kinase Kinase Inhibition Results in Biphasic Alteration of Epidermal Homeostasis with Keratinocytic Apoptosis and Pigmentation Disorders
- (2010) K. Schad et al. CLINICAL CANCER RESEARCH
- Phase I Pharmacokinetic and Pharmacodynamic Study of the Oral MAPK/ERK Kinase Inhibitor PD-0325901 in Patients with Advanced Cancers
- (2010) P. M. LoRusso et al. CLINICAL CANCER RESEARCH
- A phase 2 study of vatalanib in metastatic melanoma patients
- (2010) Natalie Cook et al. EUROPEAN JOURNAL OF CANCER
- Vertical Inhibition of the mTORC1/mTORC2/PI3K Pathway Shows Synergistic Effects against Melanoma In Vitro and In Vivo
- (2010) Johannes Werzowa et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Evaluation of the mTOR pathway in ocular (uvea and conjunctiva) melanoma
- (2010) Helena Pópulo et al. MELANOMA RESEARCH
- Inhibition of Mutated, Activated BRAF in Metastatic Melanoma
- (2010) Keith T. Flaherty et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mutations inGNA11in Uveal Melanoma
- (2010) Catherine D. Van Raamsdonk et al. NEW ENGLAND JOURNAL OF MEDICINE
- mTOR pathway activation in cutaneous melanoma is associated with poorer prognosis characteristics
- (2010) H. Pópulo et al. Pigment Cell & Melanoma Research
- Results of a Phase III, Randomized, Placebo-Controlled Study of Sorafenib in Combination With Carboplatin and Paclitaxel As Second-Line Treatment in Patients With Unresectable Stage III or Stage IV Melanoma
- (2009) Axel Hauschild et al. JOURNAL OF CLINICAL ONCOLOGY
- Final Version of 2009 AJCC Melanoma Staging and Classification
- (2009) Charles M. Balch et al. JOURNAL OF CLINICAL ONCOLOGY
- Activity of dasatinib against L576P KIT mutant melanoma: Molecular, cellular, and clinical correlates
- (2009) S. E. Woodman et al. MOLECULAR CANCER THERAPEUTICS
- A novel AKT3 mutation in melanoma tumours and cell lines
- (2008) M A Davies et al. BRITISH JOURNAL OF CANCER
- Phase II trial of imatinib mesylate in patients with metastatic melanoma
- (2008) K B Kim et al. BRITISH JOURNAL OF CANCER
- Suppression of mTOR complex 2-dependent AKT phosphorylation in melanoma cells by combined treatment with rapamycin and LY294002
- (2008) J. Werzowa et al. BRITISH JOURNAL OF DERMATOLOGY
- Akt3 and Mutant V600EB-Raf Cooperate to Promote Early Melanoma Development
- (2008) M. Cheung et al. CANCER RESEARCH
- Targeted therapy for uveal melanoma
- (2008) Pierre L. Triozzi et al. CANCER TREATMENT REVIEWS
- Phase I Pharmacokinetic and Pharmacodynamic Study of the Oral, Small-Molecule Mitogen-Activated Protein Kinase Kinase 1/2 Inhibitor AZD6244 (ARRY-142886) in Patients With Advanced Cancers
- (2008) Alex A. Adjei et al. JOURNAL OF CLINICAL ONCOLOGY
- Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomised phase III trial
- (2008) Alexander MM Eggermont et al. LANCET
- Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi
- (2008) Catherine D. Van Raamsdonk et al. NATURE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started