Targeting the TLR9–MyD88 pathway in the regulation of adaptive immune responses

TLR9-Dependent Activation of Dendritic Cells by DNA from Leishmania major Favors Th1 Cell Development and the Resolution of Lesions

(2014) F. Hkima Abou Fakher et al.   JOURNAL OF IMMUNOLOGY

Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists

(2009) Jörg Vollmer et al.   ADVANCED DRUG DELIVERY REVIEWS

Induction of type I IFN is required for overcoming tumor-specific T-cell tolerance after stem cell transplantation

(2009) I. Horkheimer et al.   BLOOD

Innate Immune Recognition of Viruses and Viral Vectors

(2009) Xiaopei Huang et al.   HUMAN GENE THERAPY

CpG-containing immunostimulatory DNA sequences elicit TNF-α–dependent toxicity in rodents but not in humans

(2009) John D. Campbell et al.   JOURNAL OF CLINICAL INVESTIGATION

The TLR9-MyD88 pathway is critical for adaptive immune responses to adeno-associated virus gene therapy vectors in mice

(2009) Jiangao Zhu et al.   JOURNAL OF CLINICAL INVESTIGATION

The DNA Sugar Backbone 2′ Deoxyribose Determines Toll-like Receptor 9 Activation

(2008) Tobias Haas et al.   IMMUNITY

Survival of lethal poxvirus infection in mice depends on TLR9, and therapeutic vaccination provides protection

(2008) Christofer Samuelsson et al.   JOURNAL OF CLINICAL INVESTIGATION

TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

(2008) Ken J. Ishii et al.   NATURE