Targeting the Nrf2 pathway against cardiovascular disease

Age-Accelerated Atherosclerosis Correlates With Failure to Upregulate Antioxidant Genes

(2009) Alan R. Collins et al.   CIRCULATION RESEARCH

Targeting the redox sensitive Nrf2–Keap1 defense pathway in cardiovascular disease: protection afforded by dietary isoflavones

(2009) Giovanni E Mann et al.   CURRENT OPINION IN PHARMACOLOGY

The Nrf2/ARE Pathway as a Potential Therapeutic Target in Neurodegenerative Disease

(2008) Marcus J. Calkins et al.   ANTIOXIDANTS & REDOX SIGNALING

KLF2 Primes the Antioxidant Transcription Factor Nrf2 for Activation in Endothelial Cells

(2008) Joost O. Fledderus et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Nuclear Factor E2-Related Factor 2-Dependent Myocardiac Cytoprotection Against Oxidative and Electrophilic Stress

(2008) Hong Zhu et al.   Cardiovascular Toxicology

Nrf2 Regulates Antioxidant Gene Expression Evoked by Oxidized Phospholipids in Endothelial Cells and Murine Arteries In Vivo

(2008) Henna-Kaisa Jyrkkänen et al.   CIRCULATION RESEARCH

Activation of NF-E2-Related Factor-2 Reverses Biochemical Dysfunction of Endothelial Cells Induced by Hyperglycemia Linked to Vascular Disease

(2008) M. Xue et al.   DIABETES

Nrf2 is critical in defense against high glucose-induced oxidative damage in cardiomyocytes

(2008) Xiaoqing He et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The Antioxidant Defense System Keap1-Nrf2 Comprises a Multiple Sensing Mechanism for Responding to a Wide Range of Chemical Compounds

(2008) M. Kobayashi et al.   MOLECULAR AND CELLULAR BIOLOGY

Dithiolethiones for cancer chemoprevention: where do we stand?

(2008) Y. Zhang et al.   MOLECULAR CANCER THERAPEUTICS

Molecular mechanisms of Nrf2-mediated antioxidant response

(2008) Wenge Li et al.   MOLECULAR CARCINOGENESIS

Disruption of Nrf2, a Key Inducer of Antioxidant Defenses, Attenuates ApoE-Mediated Atherosclerosis in Mice

(2008) Thomas E. Sussan et al.   PLoS One

Curcumin: Preventive and Therapeutic Properties in Laboratory Studies and Clinical Trials

(2007) Alexios S. Strimpakos et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxidative Stress and Antioxidants in the Pathogenesis of Pulmonary Fibrosis: A Potential Role for Nrf2

(2007) Dianne M. Walters et al.   ANTIOXIDANTS & REDOX SIGNALING

Extracellular Superoxide Dismutase Deficiency Exacerbates Pressure Overload–Induced Left Ventricular Hypertrophy and Dysfunction

(2007) Zhongbing Lu et al.   HYPERTENSION

Broccoli: A Unique Vegetable That Protects Mammalian Hearts through the Redox Cycling of the Thioredoxin Superfamily

(2007) Subhendu Mukherjee et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The Nrf2–Keap1 defence pathway: Role in protection against drug-induced toxicity

(2007) Ian M. Copple et al.   TOXICOLOGY