Proprotein convertases as therapeutic targets

Knock-out mouse models of proprotein convertases: unique functions or redundancy?

(2008) John et al.   Frontiers in Bioscience-Landmark

VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5

(2008) D. Szumska et al.   GENES & DEVELOPMENT

Proprotein convertase subtilisin/kexin type 9 (PCSK9): Hepatocyte-specific low-density lipoprotein receptor degradation and critical role in mouse liver regeneration

(2008) Ahmed Zaid et al.   HEPATOLOGY

Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells

(2008) Nathalie Scamuffa et al.   JOURNAL OF CLINICAL INVESTIGATION

Hormonal regulation of proprotein convertase subtilisin/kexin type 5 expression during ovarian follicle development in the rat

(2008) Jeong-A Bae et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Common nonsynonymous variants in PCSK1 confer risk of obesity

(2008) Michael Benzinou et al.   NATURE GENETICS

In vivo functions of the proprotein convertase PC5/6 during mouse development: Gdf11 is a likely substrate

(2008) R. Essalmani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell-surface processing of extracellular human immunodeficiency virus type 1 Vpr by proprotein convertases

(2007) Yong Xiao et al.   VIROLOGY