Boron-containing compounds: chemico-biological properties and expanding medicinal potential in prevention, diagnosis and therapy

A BODIPY-derived fluorescent probe for cellular pH measurements

(2013) Fangfei Han et al.   ANALYTICAL BIOCHEMISTRY

Reverse Relationship Between Blood Boron Level and Body Mass Index in Humans: Does It Matter for Obesity?

(2013) Mustafa Hasbahceci et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Structure–activity relationships of 6-(aminomethylphenoxy)-benzoxaborole derivatives as anti-inflammatory agent

(2013) Tsutomu Akama et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Applications of organoboron compounds in carbohydrate chemistry and glycobiology: analysis, separation, protection, and activation

(2013) Corey A. McClary et al.   CARBOHYDRATE RESEARCH

A boron dipyrromethene–phthalocyanine pentad as an artificial photosynthetic model

(2013) Jian-Yong Liu et al.   CHEMICAL COMMUNICATIONS

Reaction between Peroxynitrite and Triphenylphosphonium-Substituted Arylboronic Acid Isomers: Identification of Diagnostic Marker Products and Biological Implications

(2013) Adam Sikora et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Cytocompatibility evaluation of glycol-chitosan coated boron nitride nanotubes in human endothelial cells

(2013) Serena Del Turco et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Boron dipyrrin-porphyrin conjugates

(2013) Tamanna K. Khan et al.   COORDINATION CHEMISTRY REVIEWS

An assessment of the genetic toxicology of novel boron-containing therapeutic agents

(2013) Vic Ciaravino et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

The uniqueness of boron as a novel challenging element for drugs in pharmacology, medicine and for smart biomaterials

(2013) Clara Viñas i Teixidor   Future Medicinal Chemistry

Boron chemicals in diagnosis and therapeutics

(2013) Bhaskar C Das et al.   Future Medicinal Chemistry

Syntheses and anti-tubercular activity ofβ-substituted andα,β-disubstituted peptidylβ-aminoboronates and boronic acids

(2013) Alexey S. Gorovoy et al.   JOURNAL OF PEPTIDE SCIENCE

Boron-containing acids: Preliminary evaluation of acute toxicity and access to the brain determined by Raman scattering spectroscopy

(2013) Marvin A. Soriano-Ursúa et al.   NEUROTOXICOLOGY

Caffeine-Containing Medicines Increase the Risk of Hemorrhagic Stroke

(2013) S.-M. Lee et al.   STROKE

Fluorescent Dye Cocktail for Multiplex Drug-Site Mapping on Human Serum Albumin

(2013) Jun Cheng Er et al.   ACS Combinatorial Science

Make Caffeine Visible: a Fluorescent Caffeine “Traffic Light” Detector

(2013) Wang Xu et al.   Scientific Reports

Lewis Acid-Assisted Isotopic 18F-19F Exchange in BODIPY Dyes: Facile Generation of Positron Emission Tomography/Fluorescence Dual Modality Agents for Tumor Imaging

(2013) Shuanglong Liu et al.   Theranostics

Dopamine Sensor Based on a Boron-Doped Diamond Electrode Modified with a Polyaniline/Au Nanocomposites in the Presence of Ascorbic Acid

(2012) Min-Jung SONG et al.   ANALYTICAL SCIENCES

Boron-Containing Compounds as Preventive and Chemotherapeutic Agents for Cancer

(2012) Romulus I. Scorei et al.   Anti-Cancer Agents in Medicinal Chemistry

Reagents for Astatination of Biomolecules. 6. An Intact Antibody Conjugated with a Maleimido-closo-Decaborate(2-) Reagent via Sulfhydryl Groups Had Considerably Higher Kidney Concentrations than the Same Antibody Conjugated with an Isothiocyanato-closo-Decaborate(2-) Reagent via Lysine Amines

(2012) D. Scott Wilbur et al.   BIOCONJUGATE CHEMISTRY

Estrogenic activity of B-fluorinated o-carborane-1,2-bisphenol synthesized via SNAr reaction

(2012) Kiminori Ohta et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel sulphur-rich BODIPY systems that enable stepwise fluorescent O-atom turn-on and H2O2 neuronal system probing

(2012) Atul P. Singh et al.   CHEMICAL COMMUNICATIONS

Recognition and sensing of various species using boronic acid derivatives

(2012) Zhiqian Guo et al.   CHEMICAL COMMUNICATIONS

BODIPY dyes in photodynamic therapy

(2012) Anyanee Kamkaew et al.   CHEMICAL SOCIETY REVIEWS

Far-red to near infrared analyte-responsive fluorescent probes based on organic fluorophore platforms for fluorescence imaging

(2012) Lin Yuan et al.   CHEMICAL SOCIETY REVIEWS

Boron as a platform for new drug design

(2012) Laura Ciani et al.   Expert Opinion on Drug Discovery

Boron-based phosphodiesterase inhibitors show novel binding of boron to PDE4 bimetal center

(2012) Yvonne R. Freund et al.   FEBS LETTERS

Evaluation of new antimicrobial agents onBacillus spp. strains: docking affinity andin vitroinhibition of glutamate-racemase

(2012) Feliciano Tamay-Cach et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Human Environmental and Occupational Exposures to Boric Acid: Reconciliation with Experimental Reproductive Toxicity Data

(2012) Hermann M. Bolt et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Dietary boron: Progress in establishing essential roles in human physiology

(2012) Curtiss D. Hunt   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Effect of supplementation of different boron and copper levels to layer diets on performance, egg yolk and plasma cholesterol

(2012) Osman Olgun et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Short and long-term exposure of CNS cell lines to BPA-f a radiosensitizer for Boron Neutron Capture Therapy: safety dose evaluation by a battery of cytotoxicity tests

(2012) U. De Simone et al.   NEUROTOXICOLOGY

Is Boron a Prebiotic Element? A Mini-review of the Essentiality of Boron for the Appearance of Life on Earth

(2012) Romulus Scorei   ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES

Biological evaluation of dopamine analogues containing phenylboronic acid group as new boron carriers

(2011) Y. Ito et al.   APPLIED RADIATION AND ISOTOPES

Synthesis of conjugates of polyhedral boron compounds with tumor-seeking molecules for neutron capture therapy

(2011) V. Bregadze et al.   APPLIED RADIATION AND ISOTOPES

Crystal structure, docking study and structure–activity relationship of carborane-containing androgen receptor antagonist 3-(12-hydroxymethyl-1,12-dicarba-closo-dodecaboran-1-yl)benzonitrile

(2011) Kiminori Ohta et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Cell-based and in-silico studies on the high intrinsic activity of two boron-containing salbutamol derivatives at the human β2-adrenoceptor

(2011) Marvin A. Soriano-Ursúa et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Bodipy-diacrylate imaging probes for targeted proteins inside live cells

(2011) Jae-Jung Lee et al.   CHEMICAL COMMUNICATIONS

Visualization of tyrosinase activity in melanoma cells by a BODIPY-based fluorescent probe

(2011) Tae-Il Kim et al.   CHEMICAL COMMUNICATIONS

pH responsive self-healing hydrogels formed by boronate–catechol complexation

(2011) Lihong He et al.   CHEMICAL COMMUNICATIONS

Carbaboranes as Pharmacophores: Properties, Synthesis, and Application Strategies

(2011) Matthias Scholz et al.   CHEMICAL REVIEWS

Boron in Drug Discovery: Carboranes as Unique Pharmacophores in Biologically Active Compounds

(2011) Fatiah Issa et al.   CHEMICAL REVIEWS

Fluorescent indicators based on BODIPY

(2011) Noël Boens et al.   CHEMICAL SOCIETY REVIEWS

The formulation of polyhedral boranes for the boron neutron capture therapy of cancer

(2011) Gianpiero Calabrese et al.   DRUG DISCOVERY TODAY

Carbaboranes as pharmacophores: Similarities and differences between aspirin and asborin

(2011) Matthias Scholz et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

In Silico Carborane Docking to Proteins and Potential Drug Targets

(2011) Matteo Calvaresi et al.   Journal of Chemical Information and Modeling

Preparation, Characterization, and Screening of a High Affinity Organometallic Probe for α-Adrenergic Receptors

(2011) Anika S. Louie et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Characterization of High-Affinity 4,4-Difluoro-4-bora-3a,4a-diaza-s-indacene-Labeled Fluorescent Ligands for Human β-Adrenoceptors

(2011) Jillian G. Baker et al.   JOURNAL OF MEDICINAL CHEMISTRY

Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin-Binding Protein

(2011) Astrid Zervosen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Boron Cluster-based Development of Potent Nonsecosteroidal Vitamin D Receptor Ligands: Direct Observation of Hydrophobic Interaction between Protein Surface and Carborane

(2011) Shinya Fujii et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Give Boron a Chance: Boron Containing Compounds Reach Ionotropic and Metabotropic Transmembrane Receptors

(2011) M. A. Soriano-Ursua et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Boronic acids—A novel class of bacterial mutagen

(2011) Michael R. O’Donovan et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Pharmacokinetics of diphenylboroxazolidones ofL-α-amino acids with activity on the CNS: quantification in rat DBS by UPLC–MS/MS

(2011) Alberto García González et al.   Bioanalysis

2-Aminoethoxydiphenyl borate blocks electrical coupling and inhibits voltage-gated K+ channels in guinea pig arteriole cells

(2010) Ke-Tao Ma et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Boron transport in plants: co-ordinated regulation of transporters

(2010) Kyoko Miwa et al.   ANNALS OF BOTANY

Accelerating fluorescent sensor discovery: unbiased screening of a diversity-oriented BODIPY library

(2010) Jun-Seok Lee et al.   CHEMICAL COMMUNICATIONS

Natural and Synthetic Small Boron-Containing Molecules as Potential Inhibitors of Bacterial and Fungal Quorum Sensing

(2010) Valery M. Dembitsky et al.   CHEMICAL REVIEWS

Dutogliptin, a selective DPP4 inhibitor, improves glycaemic control in patients with type 2 diabetes: a 12-week, double-blind, randomized, placebo-controlled, multicentre trial

(2010) H. M. R. Pattzi et al.   DIABETES OBESITY & METABOLISM

The effects of some boron compounds against heavy metal toxicity in human blood

(2010) Hasan Turkez et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Boronate Derivatives of Functionally Diverse Catechols: Stability Studies

(2010) Kamal Aziz Ketuly et al.   MOLECULES

Application of Cycloaddition Reactions to the Syntheses of Novel Boron Compounds

(2010) Yinghuai Zhu et al.   MOLECULES

BODIPY probes to study peroxisome dynamics in vivo

(2010) Marie Landrum et al.   PLANT JOURNAL

Determination of non-protein cysteine in human serum by a designed BODIPY-based fluorescent probe

(2010) Jinxin Lu et al.   TALANTA

Boronic acids in medicinal chemistry: anticancer, antibacterial and antiviral applications

(2010) Paul C. Trippier et al.   MedChemComm

Drawing the PDB: Protein−Ligand Complexes in Two Dimensions

(2010) Katrin Stierand et al.   ACS Medicinal Chemistry Letters

Not boring at all. Boron is the new carbon in the quest for novel drug candidates

(2009) Philip Hunter   EMBO REPORTS

Therapeutic potential of boron-containing compounds

(2009) Stephen J Baker et al.   Future Medicinal Chemistry

Carborane Clusters in Computational Drug Design: A Comparative Docking Evaluation Using AutoDock, FlexX, Glide, and Surflex

(2009) Rohit Tiwari et al.   Journal of Chemical Information and Modeling

Permeability of the Blood-Brain Barrier to a Rhenacarborane

(2009) P. M. Hawkins et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Synthesis of a BODIPY Library and Its Application to the Development of Live Cell Glucagon Imaging Probe

(2009) Jun-Seok Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fluorescent BODIPY-Based Zn(II) Complex as a Molecular Probe for Selective Detection of Neurofibrillary Tangles in the Brains of Alzheimer’s Disease Patients

(2009) Akio Ojida et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Discovery of boron-conjugated 4-anilinoquinazoline as a prolonged inhibitor of EGFR tyrosine kinase

(2009) Hyun Seung Ban et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

(+)-(S)-trujillon, (+)-(S)-4-(2,2-diphenyl-1,3,2-oxazabolidin-5-oxo)propionic acid, a novel glutamatergic analog, modifies the activity of globus pallidus neurons by selective NMDA receptor activation

(2008) Juan M. Araujo-Alvarez et al.   CHIRALITY

Promising carboranylquinazolines for boron neutron capture therapy: Synthesis, characterization, and in vitro toxicity evaluation

(2008) Afaf R. Genady   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Use of Bodipy-labeled sphingolipid and cholesterol analogs to examine membrane microdomains in cells

(2008) David L. Marks et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Boron in Plants: Deficiency and Toxicity

(2008) Juan J. Camacho-Cristóbal et al.   Journal of Integrative Plant Biology

Activity-Based Probe for Specific Photoaffinity Labeling γ-Aminobutyric Acid B (GABAB) Receptors on Living Cells: Design, Synthesis, and Biological Evaluation

(2008) Xin Li et al.   JOURNAL OF MEDICINAL CHEMISTRY

Thymidine kinase 1 as a molecular target for boron neutron capture therapy of brain tumors

(2008) R. F. Barth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Boron transport mechanisms: collaboration of channels and transporters

(2008) Junpei Takano et al.   TRENDS IN PLANT SCIENCE