Recent progress and challenges in the discovery of new neuraminidase inhibitors

Synthesis and in vitro study of novel neuraminidase inhibitors against avian influenza virus

(2012) Jarinrat Kongkamnerd et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Recent Advances in Neuraminidase Inhibitor Development as Anti-influenza Drugs

(2012) Enguang Feng et al.   ChemMedChem

Peramivir for the treatment of influenza

(2012) Avinash K Shetty et al.   Expert Review of Anti-Infective Therapy

Crystal structure of a new benzoic acid inhibitor of influenza neuraminidase bound with a new tilt induced by overpacking subsite C6

(2012) Lalitha Venkatramani et al.   BMC STRUCTURAL BIOLOGY

Design, synthesis and biological activity of thiazolidine-4-carboxylic acid derivatives as novel influenza neuraminidase inhibitors

(2011) Yu Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Systematic review of influenza resistance to the neuraminidase inhibitors

(2011) Kristian Thorlund et al.   BMC INFECTIOUS DISEASES

The Medicinal Potential of Influenza Virus Surface Proteins: Hemagglutinin and Neuraminidase

(2011) Y. Xie et al.   CURRENT MEDICINAL CHEMISTRY

Influenza neuraminidase

(2011) Gillian M. Air   Influenza and Other Respiratory Viruses

Recent Development in Synthetic Strategies for Oseltamivir Phosphate

(2011) Masakatsu Shibasaki et al.   ISRAEL JOURNAL OF CHEMISTRY

A screening assay for neuraminidase inhibitors using neuraminidases N1 and N3 from a baculovirus expression system

(2011) Jarinrat Kongkamnerd et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

A Practical Synthesis of Zanamivir Phosphonate Congeners with Potent Anti-influenza Activity

(2011) Jiun-Jie Shie et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Influenza neuraminidase: A druggable target for natural products

(2011) Ulrike Grienke et al.   NATURAL PRODUCT REPORTS

Mechanism of 150-cavity formation in influenza neuraminidase

(2011) Rommie E. Amaro et al.   Nature Communications

Assessment of Pandemic and Seasonal Influenza A (H1N1) Virus Susceptibility to Neuraminidase Inhibitors in Three Enzyme Activity Inhibition Assays

(2010) H. T. Nguyen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Rapid Selection of Oseltamivir‐ and Peramivir‐Resistant Pandemic H1N1 Virus during Therapy in 2 Immunocompromised Hosts

(2010) Matthew J. Memoli et al.   CLINICAL INFECTIOUS DISEASES

Advances in the Structure-Based Design of the Influenza A Neuraminidase Inhibitors

(2010) Petar Mitrasinovic   CURRENT DRUG TARGETS

Biological Relevance of the Interaction between Procyanidins and Trypsin: A Multitechnique Approach

(2010) Rui Gonçalves et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Structural Relationship and Binding Mechanisms of Five Flavonoids with Bovine Serum Albumin

(2010) E-Hu Liu et al.   MOLECULES

Structures of influenza A proteins and insights into antiviral drug targets

(2010) Kalyan Das et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Permissive Secondary Mutations Enable the Evolution of Influenza Oseltamivir Resistance

(2010) J. D. Bloom et al.   SCIENCE

Interaction of alpinetin with bovine serum albumin: Probing of the mechanism and binding site by spectroscopic methods

(2010) Guowen Zhang et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Efficient Access to Oseltamivir Phosphate (Tamiflu) via theO-Trimesylate of Shikimic Acid Ethyl Ester

(2009) Martin Karpf et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design of oseltamivir analogs inhibiting neuraminidase of avian influenza virus H5N1

(2009) Thanyada Rungrotmongkol et al.   ANTIVIRAL RESEARCH

The Evolution of Influenza Resistance and Treatment

(2009) David M. Weinstock   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Antiviral Potential and Molecular Insight into Neuraminidase Inhibiting Diarylheptanoids fromAlpinia katsumadai

(2009) Ulrike Grienke et al.   JOURNAL OF MEDICINAL CHEMISTRY

Characterizing Loop Dynamics and Ligand Recognition in Human- and Avian-Type Influenza Neuraminidases via Generalized Born Molecular Dynamics and End-Point Free Energy Calculations

(2009) Rommie E. Amaro et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Some novel insights into the binding of oseltamivir and zanamivir to H5N1 and N9 influenza virus neuraminidases: A homology modeling and flexible docking study

(2009) Marija Mihajlovic et al.   JOURNAL OF THE SERBIAN CHEMICAL SOCIETY

Emergence and pandemic potential of swine-origin H1N1 influenza virus

(2009) Gabriele Neumann et al.   NATURE

Emergence of a Novel Swine-Origin Influenza A (H1N1) Virus in Humans

(2009)   NEW ENGLAND JOURNAL OF MEDICINE

Intravenous Zanamivir for Oseltamivir-Resistant 2009 H1N1 Influenza

(2009) Aditya H. Gaur et al.   NEW ENGLAND JOURNAL OF MEDICINE

Oseltamivir resistance mutation N294S in human influenza A(H5N1) virus in Egypt

(2009) Kenneth C. Earhart et al.   Journal of Infection and Public Health

A Concise and Flexible Synthesis of the Potent Anti‐Influenza Agents Tamiflu and Tamiphosphor

(2008) Jiun‐Jie Shie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CS-8958, a Prodrug of the New Neuraminidase Inhibitor R-125489, Shows Long-Acting Anti-Influenza Virus Activity

(2008) M. Yamashita et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Structure–activity relationship of flavonoids as influenza virus neuraminidase inhibitors and their in vitro anti-viral activities

(2008) Ai-Lin Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Another look at the molecular mechanism of the resistance of H5N1 influenza A virus neuraminidase (NA) to oseltamivir (OTV)

(2008) Marija L. Mihajlovic et al.   BIOPHYSICAL CHEMISTRY

On the structure-based design of novel inhibitors of H5N1 influenza A virus neuraminidase (NA)

(2008) Petar M. Mitrasinovic   BIOPHYSICAL CHEMISTRY

Developing New Antiviral Agents for Influenza Treatment: What Does the Future Hold?

(2008) Frederick Hayden   CLINICAL INFECTIOUS DISEASES

Different Synthetic Strategies of Oseltamivir Phosphate: A Potent Influenza Neuraminidase Inhibitor

(2008) Jianzhi Gong et al.   CURRENT MEDICINAL CHEMISTRY

Applications of the ArgusLab4/AScore protocol in the structure-based binding affinity prediction of various inhibitors of group-1 and group-2 influenza virus neuraminidases (NAs)

(2008) Marija L. Mihajlovic et al.   MOLECULAR SIMULATION