New pharmacological treatments for methicillin-resistantStaphylococcus aureusinfections

Novel Combinations of Vancomycin plus Ceftaroline or Oxacillin against Methicillin-Resistant Vancomycin-Intermediate Staphylococcus aureus (VISA) and Heterogeneous VISA

(2013) B. J. Werth et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

β-Lactam Antibiotics Targeting PBP1 Selectively Enhance Daptomycin Activity against Methicillin-Resistant Staphylococcus aureus

(2013) Andrew D. Berti et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Activity of Tedizolid (TR-700) against Well-Characterized Methicillin-Resistant Staphylococcus aureus Strains of Diverse Epidemiological Origins

(2013) Kenneth S. Thomson et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Randomized Phase 2 Trial To Evaluate the Clinical Efficacy of Two High-Dosage Tigecycline Regimens versus Imipenem-Cilastatin for Treatment of Hospital-Acquired Pneumonia

(2013) Julio Ramirez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Update of dalbavancin spectrum and potency in the USA: report from the SENTRY Antimicrobial Surveillance Program (2011)

(2013) Ronald N. Jones et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

All-cause mortality imbalance in the tigecycline phase 3 and 4 clinical trials

(2013) Paul C. McGovern et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Oritavancin retains bactericidal activity in vitro against standard and high inocula of heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA)

(2013) Francis F. Arhin et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Treatment of bacteraemia: meticillin-resistant Staphylococcus aureus (MRSA) to vancomycin-resistant S. aureus (VRSA)

(2013) I.M. Gould   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Tedizolid Phosphate vs Linezolid for Treatment of Acute Bacterial Skin and Skin Structure Infections

(2013) Philippe Prokocimer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Telavancin in Therapy of Experimental Aortic Valve Endocarditis in Rabbits Due to Daptomycin-Nonsusceptible Methicillin-Resistant Staphylococcus aureus

(2012) Yan Q. Xiong et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Evaluation of the Novel Combination of High-Dose Daptomycin plus Trimethoprim-Sulfamethoxazole against Daptomycin-Nonsusceptible Methicillin-Resistant Staphylococcus aureus Using anIn VitroPharmacokinetic/Pharmacodynamic Model of Simulated Endocardial Vegetations

(2012) Molly E. Steed et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In VitroActivity and Microbiological Efficacy of Tedizolid (TR-700) against Gram-Positive Clinical Isolates from a Phase 2 Study of Oral Tedizolid Phosphate (TR-701) in Patients with Complicated Skin and Skin Structure Infections

(2012) Philippe Prokocimer et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Comparative Pharmacodynamics of the New Oxazolidinone Tedizolid Phosphate and Linezolid in a Neutropenic Murine Staphylococcus aureus Pneumonia Model

(2012) Alexander J. Lepak et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Comparative Efficacies of Human Simulated Exposures of Tedizolid and Linezolid against Staphylococcus aureus in the Murine Thigh Infection Model

(2012) R. A. Keel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

High-Dose Daptomycin plus Fosfomycin Is Safe and Effective in Treating Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus Endocarditis

(2012) José M. Miró et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Daptomycin-Nonsusceptible Vancomycin-Intermediate Staphylococcus aureus Vertebral Osteomyelitis Cases Complicated by Bacteremia Treated with High-Dose Daptomycin and Trimethoprim-Sulfamethoxazole

(2012) Lisa M. Avery et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Addition of Ceftaroline to Daptomycin after Emergence of Daptomycin-Nonsusceptible Staphylococcus aureus during Therapy Improves Antibacterial Activity

(2012) Warren E. Rose et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Altering the Proclivity towards Daptomycin Resistance in Methicillin-Resistant Staphylococcus aureus Using Combinations with Other Antibiotics

(2012) Andrew D. Berti et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Fosfomycin-Daptomycin and Other Fosfomycin Combinations as Alternative Therapies in Experimental Foreign-Body Infection by Methicillin-Resistant Staphylococcus aureus

(2012) C. Garrigós et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Randomized, Evaluator-Blind, Phase 2 Study Comparing the Safety and Efficacy of Omadacycline to Those of Linezolid for Treatment of Complicated Skin and Skin Structure Infections

(2012) Gary J. Noel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vitro Activity of Ceftaroline Against Multidrug-Resistant Staphylococcus aureus and Streptococcus pneumoniae: A Review of Published Studies and the AWARE Surveillance Program (2008–2010)

(2012) David J. Farrell et al.   CLINICAL INFECTIOUS DISEASES

Does resistance in severe infections caused by methicillin-resistant Staphylococcus aureus give you the ‘creeps’?

(2012) Adrian J. Brink   Current Opinion in Critical Care

Methicillin-resistant Staphylococcus aureus bacteraemia and endocarditis treated with ceftaroline salvage therapy

(2012) T. T. Ho et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Activity of linezolid and high-dose daptomycin, alone or in combination, in an in vitro model of Staphylococcus aureus biofilm

(2012) J. Parra-Ruiz et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The use of ceftaroline fosamil in methicillin-resistant Staphylococcus aureus endocarditis and deep-seated MRSA infections: a retrospective case series of 10 patients

(2012) Jennifer C. Lin et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Efficacy and Safety of Telavancin in Clinical Trials: A Systematic Review and Meta-Analysis

(2012) Konstantinos A. Polyzos et al.   PLoS One

Successful treatment of a left ventricular assist device infection with daptomycin non-susceptible methicillin-resistantStaphylococcus aureus: case report and review of the literature

(2012) D.T. Levy et al.   Transplant Infectious Disease

Adjunctive Rifampin Is Crucial to Optimizing Daptomycin Efficacy against Rabbit Prosthetic Joint Infection Due to Methicillin-Resistant Staphylococcus aureus

(2011) Azzam Saleh-Mghir et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Comparison of the Efficacy and Safety of Oritavancin Front-Loaded Dosing Regimens to Daily Dosing: an Analysis of the SIMPLIFI Trial

(2011) Lala M. Dunbar et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Case Report: Treatment of Chronic Osteomyelitis

(2011) Cameron R. Wolfe   CLINICAL INFECTIOUS DISEASES

A Randomized, Double-Blind Phase 2 Study Comparing the Efficacy and Safety of an Oral Fusidic Acid Loading-Dose Regimen to Oral Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infections

(2011) J. Carl Craft et al.   CLINICAL INFECTIOUS DISEASES

Use of Antistaphylococcal  -Lactams to Increase Daptomycin Activity in Eradicating Persistent Bacteremia Due to Methicillin-Resistant Staphylococcus aureus: Role of Enhanced Daptomycin Binding

(2011) A. Dhand et al.   CLINICAL INFECTIOUS DISEASES

Clinical Practice Guidelines by the Infectious Diseases Society of America for the Treatment of Methicillin-Resistant Staphylococcus aureus Infections in Adults and Children: Executive Summary

(2011) Catherine Liu et al.   CLINICAL INFECTIOUS DISEASES

Clinical Practice Guidelines by the Infectious Diseases Society of America for the Treatment of Methicillin-Resistant Staphylococcus aureus Infections in Adults and Children

(2011) Catherine Liu et al.   CLINICAL INFECTIOUS DISEASES

Forgotten Antibiotics: An Inventory in Europe, the United States, Canada, and Australia

(2011) Céline Pulcini et al.   CLINICAL INFECTIOUS DISEASES

Activity of oritavancin and comparators in vitro against standard and high inocula of Staphylococcus aureus

(2011) Francis F. Arhin et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Successful treatment of methicillin-resistant Staphylococcus aureus mitral valve endocarditis with sequential linezolid and telavancin monotherapy following daptomycin failure

(2011) J. Joson et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

In vitro activity of tedizolid (TR-700) against linezolid-resistant staphylococci

(2011) I. Rodriguez-Avial et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Activities of High-Dose Daptomycin, Vancomycin, and Moxifloxacin Alone or in Combination with Clarithromycin or Rifampin in a Novel In Vitro Model of Staphylococcus aureus Biofilm

(2010) J. Parra-Ruiz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Successful Treatment of Vancomycin-Intermediate Staphylococcus aureus Pacemaker Lead Infective Endocarditis with Telavancin

(2010) L. A. Marcos et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Novel Daptomycin Combinations against Daptomycin-Nonsusceptible Methicillin-Resistant Staphylococcus aureus in an In Vitro Model of Simulated Endocardial Vegetations

(2010) M. E. Steed et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Longitudinal analysis of the in vitro activity profile of oritavancin and comparator glycopeptides against Gram-positive organisms from Europe: 2005–2008

(2010) Francis F. Arhin et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Successful treatment of methicillin-resistant Staphylococcus aureus endocarditis with telavancin

(2010) H. Nace et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

In Vitro Activity of Ceftaroline against Methicillin-Resistant Staphylococcus aureus and Heterogeneous Vancomycin-Intermediate S. aureus in a Hollow Fiber Model

(2009) C. Vidaillac et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Initial Low‐Dose Gentamicin forStaphylococcus aureusBacteremia and Endocarditis Is Nephrotoxic

(2009) Sara E. Cosgrove et al.   CLINICAL INFECTIOUS DISEASES

Multicenter evaluation of the in vitro activity of dalbavancin tested against staphylococci and streptococci in 5 European countries: results from the DECIDE Surveillance Program (2007)

(2009) Douglas J. Biedenbach et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

In vitro activities of daptomycin, tigecycline, linezolid and eight other antibiotics, alone and in combination, against 41 Staphylococcus spp. clinical isolates from bone and joint infections

(2009) B. Kuli et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Clinical significance of the pharmacokinetic and pharmacodynamic characteristics of fosfomycin for the treatment of patients with systemic infections

(2009) Nikos Roussos et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Pharmacokinetics of Dalbavancin in Patients With Renal or Hepatic Impairment

(2009) Thomas Marbury et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Oritavancin Kills Stationary-Phase and Biofilm Staphylococcus aureus Cells In Vitro

(2008) A. Belley et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Randomized, Double-Blind Trial Comparing Ceftobiprole Medocaril with Vancomycin plus Ceftazidime for the Treatment of Patients with Complicated Skin and Skin-Structure Infections

(2008) G. J. Noel et al.   CLINICAL INFECTIOUS DISEASES

Fosfomycin: Use Beyond Urinary Tract and Gastrointestinal Infections

(2008) Matthew E. Falagas et al.   CLINICAL INFECTIOUS DISEASES

Impact of biofilm on the in vitro activity of vancomycin alone and in combination with tigecycline and rifampicin against Staphylococcus aureus

(2008) W. E. Rose et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY