标题
Activin receptor-like kinase 1 as a target for anti-angiogenesis therapy
作者
关键词
-
出版物
EXPERT OPINION ON INVESTIGATIONAL DRUGS
Volume 22, Issue 11, Pages 1371-1383
出版商
Informa Healthcare
发表日期
2013-09-21
DOI
10.1517/13543784.2013.837884
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- (2013) David Fong et al. CELLULAR SIGNALLING
- Endoglin for tumor imaging and targeted cancer therapy
- (2013) Madelon Paauwe et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Outcomes of Childhood Pulmonary Arterial Hypertension in BMPR2 and ALK1 Mutation Carriers
- (2012) Ayako Chida et al. AMERICAN JOURNAL OF CARDIOLOGY
- BMP9 induces EphrinB2 expression in endothelial cells through an Alk1-BMPRII/ActRII-ID1/ID3-dependent pathway: implications for hereditary hemorrhagic telangiectasia type II
- (2012) Jai-Hyun Kim et al. ANGIOGENESIS
- Reduced Mural Cell Coverage and Impaired Vessel Integrity After Angiogenic Stimulation in the Alk1 -deficient Brain
- (2012) Wanqiu Chen et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Structure of the Alk1 Extracellular Domain and Characterization of Its Bone Morphogenetic Protein (BMP) Binding Properties
- (2012) Pardeep Mahlawat et al. BIOCHEMISTRY
- BMP9 regulates endoglin-dependent chemokine responses in endothelial cells
- (2012) K. Young et al. BLOOD
- BMP9 and BMP10 are critical for postnatal retinal vascular remodeling
- (2012) N. Ricard et al. BLOOD
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- (2012) B. Sitohy et al. CANCER RESEARCH
- Vascular Injury Triggers Krüppel-Like Factor 6 Mobilization and Cooperation With Specificity Protein 1 to Promote Endothelial Activation Through Upregulation of the Activin Receptor-Like Kinase 1 Gene
- (2012) Eva M. Garrido-Martín et al. CIRCULATION RESEARCH
- A Phase I First-in-Human Study of TRC105 (Anti-Endoglin Antibody) in Patients with Advanced Cancer
- (2012) L. S. Rosen et al. CLINICAL CANCER RESEARCH
- ALK1 Signaling Inhibits Angiogenesis by Cooperating with the Notch Pathway
- (2012) Bruno Larrivée et al. DEVELOPMENTAL CELL
- Novel targets for VEGF-independent anti-angiogenic drugs
- (2012) Marco Petrillo et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- BMP signaling in vascular diseases
- (2012) Jie Cai et al. FEBS LETTERS
- Anti-human Activin Receptor-like Kinase 1 (ALK1) Antibody Attenuates Bone Morphogenetic Protein 9 (BMP9)-induced ALK1 Signaling and Interferes with Endothelial Cell Sprouting
- (2012) Laurens A. van Meeteren et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2012) Sharon A. Townson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2012) Leonard Seghers et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
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- (2012) Wenling Zhang et al. JOURNAL OF MOLECULAR HISTOLOGY
- Retention in the endoplasmic reticulum is the underlying mechanism of some hereditary haemorrhagic telangiectasia type 2 ALK1 missense mutations
- (2012) Alistair N. Hume et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- BMP-9 Induced Endothelial Cell Tubule Formation and Inhibition of Migration Involves Smad1 Driven Endothelin-1 Production
- (2012) John E. S. Park et al. PLoS One
- Bevacizumab Attenuates VEGF-Induced Angiogenesis and Vascular Malformations in the Adult Mouse Brain
- (2012) Espen J. Walker et al. STROKE
- ALK1 as an emerging target for antiangiogenic therapy of cancer
- (2011) S. I. Cunha et al. BLOOD
- Targeting Activin Receptor-Like Kinase 1 Inhibits Angiogenesis and Tumorigenesis through a Mechanism of Action Complementary to Anti-VEGF Therapies
- (2011) Dana D. Hu-Lowe et al. CANCER RESEARCH
- Pulmonary hypertension in adult Alk1 heterozygous mice due to oxidative stress
- (2011) Mirjana Jerkic et al. CARDIOVASCULAR RESEARCH
- Age-dependent alteration of TGF-β signalling in osteoarthritis
- (2011) Peter M. van der Kraan et al. CELL AND TISSUE RESEARCH
- Interaction between alk1 and blood flow in the development of arteriovenous malformations
- (2011) P. Corti et al. DEVELOPMENT
- Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises
- (2011) Annika Armulik et al. DEVELOPMENTAL CELL
- Exploring anti-TGF-β therapies in cancer and fibrosis
- (2011) Lukas J. A. C. Hawinkels et al. GROWTH FACTORS
- TGF-β signaling in endothelial cells, but not neuroepithelial cells, is essential for cerebral vascular development
- (2011) Ha-Long Nguyen et al. LABORATORY INVESTIGATION
- ALK1 heterozygosity delays development of late normal tissue damage in the irradiated mouse kidney
- (2011) Marion Scharpfenecker et al. RADIOTHERAPY AND ONCOLOGY
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- (2010) Espen J. Walker et al. ANNALS OF NEUROLOGY
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- (2010) N. Ricard et al. BLOOD
- Characterization of the human Activin-A receptor type II-like kinase 1 (ACVRL1) promoter and its regulation by Sp1
- (2010) Eva M Garrido-Martin et al. BMC MOLECULAR BIOLOGY
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- (2010) L. J. A. C. Hawinkels et al. CANCER RESEARCH
- Transforming growth factor-β and the hallmarks of cancer
- (2010) Maozhen Tian et al. CELLULAR SIGNALLING
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- (2010) Jinyong Luo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2010) Sara I. Cunha et al. JOURNAL OF EXPERIMENTAL MEDICINE
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- (2010) D. Mitchell et al. MOLECULAR CANCER THERAPEUTICS
- The emerging role of TGF-β superfamily coreceptors in cancer
- (2009) Carmelo Bernabeu et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- ALK1 signaling regulates early postnatal lymphatic vessel development
- (2009) K. Niessen et al. BLOOD
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- (2009) E. S. Shao et al. BLOOD
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- (2009) E. N. Blaney Davidson et al. JOURNAL OF IMMUNOLOGY
- Endoglin in angiogenesis and vascular diseases
- (2008) Peter ten Dijke et al. ANGIOGENESIS
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- (2008) Gregory D. Cuny et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Roles of TGFβ in metastasis
- (2008) David Padua et al. CELL RESEARCH
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- (2008) Marie-José Goumans et al. CELL RESEARCH
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- (2007) S. O. Park et al. BLOOD
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