期刊
EXPERT OPINION ON DRUG SAFETY
卷 7, 期 6, 页码 679-690出版社
TAYLOR & FRANCIS LTD
DOI: 10.1517/14740330802410462
关键词
acute interstitial nephritis; acute tubular necrosis; aminoglycosides; amphotericin B; ciclosporin; NSAIDs; obstructive nephropathy; radiocontrast dye
The epidemiology of drug-induced renal disorders is a complex topic. Drug-associated nephrotoxicity accounts for 18 - 27% of all acute kidney injury cases in US hospitals. Medications can affect all aspects of the kidney, and drugs that are associated with renal dysfunction are used commonly in clinical practice. The article reviews six major mechanisms of drug-induced renal dysfunction as well as lists the major medications involved. NSAIDs, aminoglycosides, amphotericin B and calcineurin inhibitors are just some examples of drugs that contribute to renal dysfunction. The medical community must be aware of patient risk factors for nephrotoxicity, as well as the drug's inherent nephrotoxic potential, when prescribing and administering medications.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据