Polymorphisms of the drug transporters ABCB1, ABCG2, ABCC2 and ABCC3 and their impact on drug bioavailability and clinical relevance
出版年份 2014 全文链接
标题
Polymorphisms of the drug transporters ABCB1, ABCG2, ABCC2 and ABCC3 and their impact on drug bioavailability and clinical relevance
作者
关键词
-
出版物
Expert Opinion on Drug Metabolism & Toxicology
Volume 10, Issue 10, Pages 1337-1354
出版商
Informa Healthcare
发表日期
2014-08-27
DOI
10.1517/17425255.2014.952630
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- MicroRNAs and their relevance to ABC transporters
- (2014) Sierk Haenisch et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Inherited Disorders of Bilirubin Transport and Conjugation: New Insights Into Molecular Mechanisms and Consequences
- (2014) Serge Erlinger et al. GASTROENTEROLOGY
- Genetic variants may play an important role in mRNA–miRNA interaction
- (2014) Anneke N. Werk et al. Pharmacogenetics and Genomics
- Efffect of theABCC3-211C/Tpolymorphism on clopidogrel responsiveness in patients with percutaneous coronary intervention
- (2013) Jian-Jun Zou et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Multidrug Resistance-Associated Protein 2 (MRP2/ABCC2) Haplotypes Significantly Affect the Pharmacokinetics of Tacrolimus in Kidney Transplant Recipients
- (2013) Ken Ogasawara et al. CLINICAL PHARMACOKINETICS
- ABCB1 gene polymorphisms are associated with fatal intoxications involving venlafaxine but not citalopram
- (2013) L. Karlsson et al. INTERNATIONAL JOURNAL OF LEGAL MEDICINE
- Linkage Disequilibrium between Polymorphisms of ABCB1 and ABCC2 to Predict the Treatment Outcome of Malaysians with Complex Partial Seizures on Treatment with Carbamazepine Mono-Therapy at the Kuala Lumpur Hospital
- (2013) Soobitha Subenthiran et al. PLoS One
- Increased Expression of P-Glycoprotein and Doxorubicin Chemoresistance of Metastatic Breast Cancer Is Regulated by miR-298
- (2012) Lili Bao et al. AMERICAN JOURNAL OF PATHOLOGY
- The effects of CYP3A4, CYP3A5, ABCB1, ABCC2, ABCG2 and SLCO1B3 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of docetaxel in nasopharyngeal carcinoma patients
- (2011) Sin-Chi Chew et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Effect of Genetic Polymorphisms of SLC28A1, ABCG2, and ABCC4 on Bioavailability of Mizoribine in Healthy Japanese Males
- (2011) Miki Fukao et al. Drug Metabolism and Pharmacokinetics
- Impact of ABCC2 genotype on antiepileptic drug response in Caucasian patients with childhood epilepsy
- (2011) Mike Ufer et al. Pharmacogenetics and Genomics
- Impact ofABCG2polymorphisms on the clinical outcome and toxicity of gefitinib in non-small-cell lung cancer patients
- (2011) Clara Lemos et al. PHARMACOGENOMICS
- Association ofABCB1gene polymorphisms and their haplotypes with response to antiepileptic drugs: a systematic review and meta-analysis
- (2011) Batoul Sadat Haerian et al. PHARMACOGENOMICS
- Polymorphism in multidrug resistance-associated protein gene 3 is associated with outcomes in childhood acute lymphoblastic leukemia
- (2011) M Ansari et al. PHARMACOGENOMICS JOURNAL
- An update on ABCB1 pharmacogenetics: insights from a 3D model into the location and evolutionary conservation of residues corresponding to SNPs associated with drug pharmacokinetics
- (2011) S J Wolf et al. PHARMACOGENOMICS JOURNAL
- Genetic variation in the ABCC2 gene is associated with dose decreases or switches to other cholesterol-lowering drugs during simvastatin and atorvastatin therapy
- (2011) M L Becker et al. PHARMACOGENOMICS JOURNAL
- Hepatic Metabolism and Transporter Gene Variants Enhance Response to Rosuvastatin in Patients With Acute Myocardial Infarction
- (2010) Kristian M. Bailey et al. Circulation-Cardiovascular Genetics
- Role of ATP-Binding Cassette and Solute Carrier Transporters in Erlotinib CNS Penetration and Intracellular Accumulation
- (2010) M. A. Elmeliegy et al. CLINICAL CANCER RESEARCH
- Genetic Polymorphisms Associated with a Prolonged Progression-Free Survival in Patients with Metastatic Renal Cell Cancer Treated with Sunitinib
- (2010) A. A. M. van der Veldt et al. CLINICAL CANCER RESEARCH
- ABCG2 Polymorphism Is Associated With the Low-Density Lipoprotein Cholesterol Response to Rosuvastatin
- (2010) B Tomlinson et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Explaining variability in ciclosporin exposure in adult kidney transplant recipients
- (2010) Rogier R. Press et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- CYP2C19 Genetic Variants Affect Nelfinavir Pharmacokinetics and Virologic Response in HIV-1–Infected Children Receiving Highly Active Antiretroviral Therapy
- (2010) Akihiko Saitoh et al. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
- Do Drug Transporter (ABCB1) SNPs Influence Cyclosporine and Tacrolimus Dose Requirements and Renal Allograft Outcome in the Posttransplantation Period?
- (2010) Ranjana Singh et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Influence of CYP3A5 and drug transporter polymorphisms on imatinib trough concentration and clinical response among patients with chronic phase chronic myeloid leukemia
- (2010) Naoto Takahashi et al. JOURNAL OF HUMAN GENETICS
- Structure of a human multidrug transporter in an inward-facing conformation
- (2010) Mark F. Rosenberg et al. JOURNAL OF STRUCTURAL BIOLOGY
- Impact of ABCC2 haplotypes on transcriptional and posttranscriptional gene regulation and function
- (2010) S Laechelt et al. PHARMACOGENOMICS JOURNAL
- Flavopiridol Pharmacogenetics: Clinical and Functional Evidence for the Role of SLCO1B1/OATP1B1 in Flavopiridol Disposition
- (2010) Wenjun Ni et al. PLoS One
- Impact of functional ABCG2 polymorphisms on the adverse effects of gefitinib in Japanese patients with non–small-cell lung cancer
- (2009) Keiichi Akasaka et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Additive effects of drug transporter genetic polymorphisms on irinotecan pharmacokinetics/pharmacodynamics in Japanese cancer patients
- (2009) Kimie Sai et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Clinical Relevance of a Pharmacogenetic Approach Using Multiple Candidate Genes to Predict Response and Resistance to Imatinib Therapy in Chronic Myeloid Leukemia
- (2009) D. H. Kim et al. CLINICAL CANCER RESEARCH
- ABCG2 Polymorphism Markedly Affects the Pharmacokinetics of Atorvastatin and Rosuvastatin
- (2009) J E Keskitalo et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- ABC Transporters in Drug-Refractory Epilepsy: Limited Clinical Significance of Pharmacogenetics?
- (2009) I Cascorbi CLINICAL PHARMACOLOGY & THERAPEUTICS
- Influence of CYP3A5 and ABCB1 gene polymorphisms on calcineurin inhibitor-related neurotoxicity after hematopoietic stem cell transplantation
- (2009) Masakatsu Yanagimachi et al. CLINICAL TRANSPLANTATION
- Association of the c.3972C>T Variant of the Multidrug Resistance-Associated Protein 2 Gene (MRP2/ABCC2) with Susceptibility to Bile Duct Cancer
- (2009) A. Höblinger et al. DIGESTION
- Polymorphism of the MDR1/ABCB1 C3435T drug-transporter and resistance to anticonvulsant drugs: A meta-analysis
- (2009) Facundo Garcia Bournissen et al. EPILEPSIA
- Population pharmacokinetics of erlotinib and its pharmacokinetic/pharmacodynamic relationships in head and neck squamous cell carcinoma
- (2009) Fabienne Thomas et al. EUROPEAN JOURNAL OF CANCER
- The antinociceptive effect and adverse drug reactions of oxycodone in human experimental pain in relation to genetic variations in the OPRM1 and ABCB1 genes
- (2009) Stine T. Zwisler et al. FUNDAMENTAL & CLINICAL PHARMACOLOGY
- ABCB1 and ABCG2 proteins, their functional activity and gene expression in concert with drug sensitivity of leukemia cells
- (2009) Arcadi I. Svirnovski et al. Hematology
- Comprehensive Pharmacogenetic Analysis of Irinotecan Neutropenia and Pharmacokinetics
- (2009) Federico Innocenti et al. JOURNAL OF CLINICAL ONCOLOGY
- Pharmacogenetic Pathway Analysis for Determination of Sunitinib-Induced Toxicity
- (2009) Nielka P. van Erp et al. JOURNAL OF CLINICAL ONCOLOGY
- Oral Sulfasalazine as a Clinical BCRP Probe Substrate: Pharmacokinetic Effects of Genetic Variation (C421A) and Pantoprazole Coadministration
- (2009) Kimberly K. Adkison et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Common ATP-binding cassette B1 variants are associated with increased digoxin serum concentration
- (2009) Albert-Jan L.H.J. Aarnoudse et al. Pharmacogenetics and Genomics
- Influence of ABCB1 genetic polymorphisms on cyclosporine intracellular concentration in transplant recipients
- (2009) Séverine Crettol et al. Pharmacogenetics and Genomics
- Non-response to antiepileptic pharmacotherapy is associated with the ABCC2 −24C>T polymorphism in young and adult patients with epilepsy
- (2009) Mike Ufer et al. Pharmacogenetics and Genomics
- Cross-sectional analysis of the influence of currently known pharmacogenetic modulators on opioid therapy in outpatient pain centers
- (2009) Jörn Lötsch et al. Pharmacogenetics and Genomics
- Association betweenABCC2polymorphism and lopinavir accumulation in peripheral blood mononuclear cells of HIV-infected patients
- (2009) Laure Elens et al. PHARMACOGENOMICS
- Different effects of theABCG2c.421C>A SNP on the pharmacokinetics of fluvastatin, pravastatin and simvastatin
- (2009) Jenni E Keskitalo et al. PHARMACOGENOMICS
- Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout
- (2009) O. M. Woodward et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
- (2009) S. G. Aller et al. SCIENCE
- Common Defects of ABCG2, a High-Capacity Urate Exporter, Cause Gout: A Function-Based Genetic Analysis in a Japanese Population
- (2009) H. Matsuo et al. Science Translational Medicine
- Meta-Analysis of the Effect of MDR1 C3435T Polymorphism on Cyclosporine Pharmacokinetics
- (2008) Zhi-Ping Jiang et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- Involvement of NHERF1 in apical membrane localization of MRP4 in polarized kidney cells
- (2008) Md. Tozammel Hoque et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells
- (2008) Hua Zhu et al. BIOCHEMICAL PHARMACOLOGY
- Multidrug resistance gene (MDR1) polymorphisms are associated with major molecular responses to standard-dose imatinib in chronic myeloid leukemia
- (2008) S. Dulucq et al. BLOOD
- TheABCG2C421A polymorphism does not affect oral nitrofurantoin pharmacokinetics in healthy Chinese male subjects
- (2008) Kimberly K. Adkison et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Genetic variation and response to morphine in cancer patients
- (2008) Joy R. Ross et al. CANCER
- Functional Genomics Identifies ABCC3 as a Mediator of Taxane Resistance in HER2-Amplified Breast Cancer
- (2008) C. O'Brien et al. CANCER RESEARCH
- ABCG2Q141K polymorphism is associated with chemotherapy-induced diarrhea in patients with diffuse large B-cell lymphoma who received frontline rituximab plus cyclophosphamide/doxorubicin/ vincristine/prednisone chemotherapy
- (2008) In-Suk Kim et al. CANCER SCIENCE
- Influence of ABCB1 and ABCG2 polymorphisms on doxorubicin disposition in Asian breast cancer patients
- (2008) Suman Lal et al. CANCER SCIENCE
- Telmisartan pharmacokinetics in Japanese renal transplant recipients
- (2008) Masatomo Miura et al. CLINICA CHIMICA ACTA
- Population Pharmacokinetics and Pharmacogenetics of Imatinib in Children and Adults
- (2008) A. Petain et al. CLINICAL CANCER RESEARCH
- Influence of CYP3A4, CYP3A5, and ABCB1 Genotype and Expression on Budesonide Pharmacokinetics: A Possible Role of Intestinal CYP3A4 Expression
- (2008) M Ufer et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- The clinical impact of pharmacogenetics on the treatment of epilepsy
- (2008) Wolfgang Löscher et al. EPILEPSIA
- ABCB1 (MDR1) genetic variants are associated with methadone doses required for effective treatment of heroin dependence
- (2008) Orna Levran et al. HUMAN MOLECULAR GENETICS
- Polymorphisms inABCG2,ABCC3andCNT1genes and their possible impact on chemotherapy outcome of lung cancer patients
- (2008) Phillip J. Müller et al. INTERNATIONAL JOURNAL OF CANCER
- Pharmacogenomic and Pharmacokinetic Determinants of Erlotinib Toxicity
- (2008) Charles M. Rudin et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase II Study of Imatinib in Patients With Recurrent Gliomas of Various Histologies: A European Organisation for Research and Treatment of Cancer Brain Tumor Group Study
- (2008) Eric Raymond et al. JOURNAL OF CLINICAL ONCOLOGY
- Genetic Variation in Efflux Transporters Influences Outcome to Methotrexate Therapy in Patients with Psoriasis
- (2008) Richard B. Warren et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Substrate-Dependent Effects of Human ABCB1 Coding Polymorphisms
- (2008) J. M. Gow et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- A Novel Human Multidrug Resistance Gene MDR1 Variant G571A (G191R) Modulates Cancer Drug Resistance and Efflux Transport
- (2008) Z. Yang et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Targeting the leukemic stem cell: the Holy Grail of leukemia therapy
- (2008) N Misaghian et al. LEUKEMIA
- C3435T polymorphism of the MDR1 gene is not associated with P-glycoprotein function of leukemic blasts and clinical outcome in patients with acute myeloid leukemia
- (2008) Eun-Hye Hur et al. LEUKEMIA RESEARCH
- Polymorphisms in transporter and phase II metabolism genes as potential modifiers of the predisposition to and treatment outcome of de novo acute myeloid leukemia in Israeli ethnic groups
- (2008) Phillip Müller et al. LEUKEMIA RESEARCH
- One of the hottest topics in epileptology: ABC proteins. Their inhibition may be the future for patients with intractable seizures
- (2008) John R. Hughes NEUROLOGICAL RESEARCH
- Influence of genetic polymorphisms on intestinal expression and rifampicin-type induction of ABCC2 and on bioavailability of talinolol
- (2008) Sierk Haenisch et al. Pharmacogenetics and Genomics
- Functional analysis of nonsynonymous single nucleotide polymorphism type ATP-binding cassette transmembrane transporter subfamily C member 3
- (2008) Kazuhiro Kobayashi et al. Pharmacogenetics and Genomics
- Breast cancer resistance protein (ABCG2) and drug disposition: intestinal expression, polymorphisms and sulfasalazine as an in vivo probe
- (2008) Bradley L. Urquhart et al. Pharmacogenetics and Genomics
- Pharmacokinetics of mycophenolate mofetil and its glucuronide metabolites in healthy volunteers
- (2008) Eric Lévesque et al. PHARMACOGENOMICS
- Modulation of P-Glycoprotein at the Blood-Brain Barrier: Opportunities to Improve Central Nervous System Pharmacotherapy
- (2008) D. S. Miller et al. PHARMACOLOGICAL REVIEWS
- Influence of uridine diphosphate (UDP)-glucuronosyltransferases and ABCC2 genetic polymorphisms on the pharmacokinetics of mycophenolic acid and its metabolites in Chinese renal transplant recipients
- (2008) W.-X. Zhang et al. XENOBIOTICA
- No Influence of ABCB1 Haplotypes on Methadone Dosage Requirement
- (2007) S Crettol et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
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