Cytochrome P450-mediated metabolism in brain: functional roles and their implications

Is There a Relationship Between the Substrate Preferences and Structural Flexibility of Cytochromes P450?

(2012) Michal Otyepka et al.   CURRENT DRUG METABOLISM

Multiple, Ligand-dependent Routes from the Active Site of Cytochrome P450 2C9

(2012) Vlad Cojocaru et al.   CURRENT DRUG METABOLISM

Substrate selectivity of drug-metabolizing cytochrome P450s predicted from crystal structures andin silicomodeling

(2012) Dong Dong et al.   DRUG METABOLISM REVIEWS

Fenofibrate Reduces Mortality and Precludes Neurological Deficits in Survivors in Murine Model of Japanese Encephalitis Viral Infection

(2012) Neha Sehgal et al.   PLoS One

Cytochrome P4504f, a potential therapeutic target limiting neuroinflammation

(2011) Neha Sehgal et al.   BIOCHEMICAL PHARMACOLOGY

Cytochrome P450 eicosanoids and cerebral vascular function

(2011) John D. Imig et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Cytochrome P450 enzymes in the brain: emerging evidence of biological significance

(2011) Charmaine S. Ferguson et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

ABC transporters and cytochromes P450 in the human central nervous system: influence on brain pharmacokinetics and contribution to neurodegenerative disorders

(2010) Fabien Dutheil et al.   Expert Opinion on Drug Metabolism & Toxicology

Blood–brain interfaces and cerebral drug bioavailability

(2009) J.-F. Ghersi-Egea et al.   REVUE NEUROLOGIQUE

Xenobiotic-Induced Transcriptional Regulation of Xenobiotic Metabolizing Enzymes of the Cytochrome P450 Superfamily in Human Extrahepatic Tissues

(2008) Petr Pavek et al.   CURRENT DRUG METABOLISM

Drug Metabolism in Human Brain: High Levels of Cytochrome P4503A43 in Brain and Metabolism of Anti-Anxiety Drug Alprazolam to Its Active Metabolite

(2008) Varsha Agarwal et al.   PLoS One