Triazole antifungal agents drug–drug interactions involving hepatic cytochrome P450

Rhabdomyolysis Induced by Simvastatin-Fluconazole Combination

(2016) Ribhi Hazin et al.   JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION

Effect of oral itraconazole on the pharmacokinetics of tacrolimus in a hematopoietic stem cell transplant recipient with CYP3A5*3/*3

(2010) Miho Nara et al.   AMERICAN JOURNAL OF HEMATOLOGY

Potential impact of cytochrome P450 3A5 in human liver on drug interactions with triazoles

(2010) Hiroshi Yamazaki et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Accurate Prediction of Dose-Dependent CYP3A4 Inhibition by Itraconazole and Its Metabolites From In Vitro Inhibition Data

(2010) I Templeton et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Investigation into UDP-Glucuronosyltransferase (UGT) Enzyme Kinetics of Imidazole- and Triazole-Containing Antifungal Drugs in Human Liver Microsomes and Recombinant UGT Enzymes

(2010) K. Bourcier et al.   DRUG METABOLISM AND DISPOSITION

Drug interaction between voriconazole and calcineurin inhibitors in allogeneic hematopoietic stem cell transplant recipients

(2009) T Mori et al.   BONE MARROW TRANSPLANTATION

Pharmacokinetics, metabolism and bioavailability of the triazole antifungal agent voriconazole in relation to CYP2C19 genotype

(2009) Ina Scholz et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Pharmacogenetics of CYP2C19: functional and clinical implications of a new variant CYP2C19*17

(2009) Alain Li-Wan-Po et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Effects of oral posaconazole on the pharmacokinetic properties of oral and intravenous midazolam: A phase I, randomized, open-label, crossover study in healthy volunteers

(2009) Gopal Krishna et al.   CLINICAL THERAPEUTICS

Genetic Polymorphism of the Human Cytochrome P450 2C9 Gene and Its Clinical Significance

(2009) Bo Wang et al.   CURRENT DRUG METABOLISM

Effects of oral posaconazole on the pharmacokinetics of sirolimus

(2009) Allen Moton et al.   CURRENT MEDICAL RESEARCH AND OPINION

In Vitro Hepatic Metabolism Explains Higher Clearance of Voriconazole in Children versus Adults: Role of CYP2C19 and Flavin-Containing Monooxygenase 3

(2009) S. B. Yanni et al.   DRUG METABOLISM AND DISPOSITION

Polymorphism of human cytochrome P450 enzymes and its clinical impact

(2009) Shu-Feng Zhou et al.   DRUG METABOLISM REVIEWS

Effects of Oral Posaconazole on the Pharmacokinetics of Atazanavir Alone and With Ritonavir or With Efavirenz in Healthy Adult Volunteers

(2009) Gopal Krishna et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Clinically relevant drug interactions of current antifungal agents

(2009) Paul O. Gubbins et al.   MYCOSES

Comprehensive In Vitro Analysis of Voriconazole Inhibition of Eight Cytochrome P450 (CYP) Enzymes: Major Effect on CYPs 2B6, 2C9, 2C19, and 3A

(2008) S. Jeong et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pharmacokinetic interactions of efavirenz and voriconazole in healthy volunteers

(2008) Bharat Damle et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Role of Flavin-Containing Monooxygenase in Oxidative Metabolism of Voriconazole by Human Liver Microsomes

(2008) S. B. Yanni et al.   DRUG METABOLISM AND DISPOSITION

The CYP2C19 ultra-rapid metabolizer genotype influences the pharmacokinetics of voriconazole in healthy male volunteers

(2008) Guo Wang et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

CYP2C19Genotype Is a Major Factor Contributing to the Highly Variable Pharmacokinetics of Voriconazole

(2008) Johanna Weiss et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Effects of CYP3A5 and MDR1 single nucleotide polymorphisms on drug interactions between tacrolimus and fluconazole in renal allograft recipients

(2008) Dirk R. Kuypers et al.   Pharmacogenetics and Genomics

Cytochrome P450 and Chemical Toxicology

(2007) F. Peter Guengerich   CHEMICAL RESEARCH IN TOXICOLOGY

Pharmacokinetic Interaction Between Voriconazole and Efavirenz at Steady State in Healthy Male Subjects

(2007) Ping Liu et al.   JOURNAL OF CLINICAL PHARMACOLOGY